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公开(公告)号：EP2424840A1
公开(公告)日：2012-03-07
申请号：EP10715470.0
申请日：2010-04-26
发明人： KOWALSKI, Jennifer A. , MARSHALL, Daniel Richard , PROKOPOWICZ, Anthony S. III , SCHLYER, Sabine , SIBLEY, Robert , SORCEK, Ronald John , WU, Di , WU, Frank , YOUNG, Erick Richard Roush
IPC分类号： C07D209/48 , C07D213/26 , C07D213/56 , C07D213/65 , C07D213/74 , C07D217/00 , C07D231/10 , C07D233/90 , C07D235/04 , C07D239/34 , C07D239/42 , C07D277/30 , C07D307/68 , C07D317/68 , C07D319/18
CPC分类号： C07D471/04 , C07D209/48 , C07D213/26 , C07D213/56 , C07D213/65 , C07D213/74 , C07D217/00 , C07D231/10 , C07D233/90 , C07D235/04 , C07D239/34 , C07D239/42 , C07D277/30 , C07D295/185 , C07D307/68 , C07D317/68 , C07D319/18 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D413/12 , C07D417/12 , C07D491/08
摘要： The present invention relates to compounds of formula (I), and pharmaceutically acceptable salts thereof, wherein R
1 to R
5 , A, B, D and X are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.-
公开(公告)号：EP2424840B1
公开(公告)日：2014-08-06
申请号：EP10715470.0
申请日：2010-04-26
发明人： KOWALSKI, Jennifer A. , MARSHALL, Daniel Richard , PROKOPOWICZ, Anthony S. III , SCHLYER, Sabine , SIBLEY, Robert , SORCEK, Ronald John , WU, Di , WU, Frank , YOUNG, Erick Richard Roush
IPC分类号： A61K31/495 , A61P29/00 , C07D403/12 , C07D401/14 , C07D491/08 , C07D213/74 , C07D217/00 , C07D317/68 , C07D319/18 , C07D231/10 , C07D233/90 , C07D235/04 , C07D413/12 , C07D417/12 , C07D471/12 , C07D295/185
CPC分类号： C07D471/04 , C07D209/48 , C07D213/26 , C07D213/56 , C07D213/65 , C07D213/74 , C07D217/00 , C07D231/10 , C07D233/90 , C07D235/04 , C07D239/34 , C07D239/42 , C07D277/30 , C07D295/185 , C07D307/68 , C07D317/68 , C07D319/18 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D413/12 , C07D417/12 , C07D491/08
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公开(公告)号：EP2424858A1
公开(公告)日：2012-03-07
申请号：EP10715474.2
申请日：2010-04-27
发明人： GINN, John David , MARSHALL, Daniel Richard , PROKOPOWICZ, Anthony S. , SCHYLER, Sabine , SIBLEY, Robert , TURNER, Michael Robert , WU, Di , WU, Frank
IPC分类号： C07D401/12 , C07D403/06 , C07D403/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D513/04 , A61K31/19 , A61P29/00
CPC分类号： C07D403/06 , C07D401/12 , C07D403/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D513/04
摘要： The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R
1 to R
6 , A, B, X, Y and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.-
公开(公告)号：EP2424858B1
公开(公告)日：2014-05-14
申请号：EP10715474.2
申请日：2010-04-27
发明人： GINN, John David , MARSHALL, Daniel Richard , PROKOPOWICZ, Anthony S. , SCHYLER, Sabine , SIBLEY, Robert , TURNER, Michael Robert , WU, Di , WU, Frank
IPC分类号： C07D401/12 , C07D403/06 , C07D403/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D513/04 , A61K31/19 , A61P29/00
CPC分类号： C07D403/06 , C07D401/12 , C07D403/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D513/04
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公开(公告)号：EP2638012A1
公开(公告)日：2013-09-18
申请号：EP11785240.0
申请日：2011-11-07
发明人： BOYER, Stephen J. , GUO, Xin , WU, Di , WU, Frank
IPC分类号： C07D213/75 , C07D401/04 , C07D413/04 , C07D417/14 , A61K31/443 , A61K31/4436 , A61K31/4439 , A61K31/4418 , A61K31/44 , A61P5/42
CPC分类号： C07D401/04 , C07D213/75 , C07D413/04 , C07D417/14
摘要： Mineralocorticoid receptor antagonists, of which formula (1) is exemplary.
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