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1.发明公开CYANOTHIOPHENE, DEREN HERSTELLUNG UND DEREN VERWENDUNG ALS ARZNEIMITTEL 审中-公开Cyanothiophenes其制备及其作为药物
公开(公告)号：EP1807411A1
公开(公告)日：2007-07-18
申请号：EP05797301.8
申请日：2005-10-18
发明人： ANDERSKEWITZ, Ralf , MORSCHHÄUSER, Gerd , STREICHER, Rüdiger , TRIESELMANN, Thomas , WALTER, Rainer
IPC分类号： C07D333/38 , A61K31/381 , A61P3/10
CPC分类号： C07D333/38 , C07D409/12
摘要： The invention relates to cyanothiophenes of general formula (I), in which the R's are defined in the claims, and relates to their tautomers, stereoisomers, mixtures and salts that have valuable pharmacological properties, in particular, a glucagon receptor-antagonistic action.
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2.发明公开VERWENDUNG VON SUBSTITUIERTEN 2-PHENYLBENZIMIDAZOLEN ALS ARZNEIMITTEL 审中-公开取代的2- PHENYLBENZIMIDAZOLEN作为药品的使用
公开(公告)号：EP1585517A1
公开(公告)日：2005-10-19
申请号：EP03767827.3
申请日：2003-12-23
发明人： STREICHER, Rüdiger , MACK, Jürgen , WALTER, Rainer , KONETZKI, Ingo , TRIESELMANN, Thomas , AUSTEL, Volkhard
IPC分类号： A61K31/4184 , A61P3/10 , C07D235/18 , C07D403/12 , C07D401/12 , C07D417/12 , C07D409/12 , C07D405/12 , C07D409/04 , C07D401/04 , C07D405/14
CPC分类号： C07D401/04 , A61K31/4184 , C07D235/18 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D405/04 , C07D405/12 , C07D409/04 , C07D409/12 , C07D409/14 , C07D417/04 , C07D417/12 , C07D417/14
摘要： The invention relates to the use of a substituted 2-phenylbenzimidazole of formula (I), where R1, R2, R3, R4, R5 and m have the meanings given in the claims, for the production of a medicament for the treatment or prevention of diseases in which glucagon receptors are implicated and novel compounds of formula (I), where R1 is a group of formula (II).
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