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1.发明公开SYSTEM AND METHOD FOR DELIVERING MODULATED SUB-THRESHOLD THERAPY TO A PATIENT 有权用于向患者提供调节的亚阈值治疗的系统和方法
公开(公告)号：EP3102283A1
公开(公告)日：2016-12-14
申请号：EP15702346.6
申请日：2015-01-21
CPC分类号： A61N1/36164 , A61N1/0551 , A61N1/36071 , A61N1/36125 , A61N1/36132 , A61N1/3615 , A61N1/37247
摘要： A neuromodulation system configured for providing sub-threshold neuromodulation therapy to a patient. The neuromodulation system comprises a neuromodulation lead having at least one electrode configured for being implanted along a spinal cord of a patient, a plurality of electrical terminals configured for being respectively coupled to the at least one electrode, modulation output circuitry configured for delivering sub-threshold modulation energy to active ones of the at least one electrode, and control/processing circuitry configured for selecting a percentage from a plurality of percentages based on a known longitudinal location of the neuromodulation lead relative to the spinal cord, computing an amplitude value as a function of the selected percentage, and controlling the modulation output circuitry to deliver sub-threshold modulation energy to the patient at the computed amplitude value.
摘要翻译： 神经调节系统被配置用于向患者提供亚阈值神经调节疗法。 所述神经调节系统包括神经调节引线，所述神经调节引线具有被配置为沿着患者的脊髓被植入的至少一个电极，被配置为分别耦合到所述至少一个电极的多个电端子，被配置用于传送亚阈值 调制能量给所述至少一个电极中的活动电极;以及控制/处理电路，其被配置用于基于神经调节导线相对于脊髓的已知纵向位置从多个百分比中选择百分比，计算振幅值作为函数 并且控制调制输出电路以在所计算的幅度值下向患者传递亚阈值调制能量。
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公开(公告)号：EP3583979A1
公开(公告)日：2019-12-25
申请号：EP19179413.0
申请日：2014-03-15
发明人： Vansickle, Dennis Allen , Lee, Dongchul , Kothandaraman, Sridhar , Doan, Que T. , Zhu, Changfang , Parramon, Jordi , Holley, Justin , Hershey, Bradley L. , Gillespie, Christopher E. , Carbunaru, Rafael , Wahab, Nazim
摘要： The present invention relates to a neuromodulation system comprising an external control device for programming an implantable neuromodulator coupled to an electrode array implanted within a patient, the external control device comprising:
a user interface;
telemetry circuitry configured for communicating with the neuromodulator; and
controller/processor circuitry configured for, in response to input into the user interface, directing the neuromodulator via the telemetry circuitry to deliver super-threshold electrical modulation energy in accordance with a super-threshold modulation parameter set, and sub-threshold electrical modulation energy in accordance with a sub-threshold modulation parameter set, wherein the super-threshold modulation parameter set and the sub-threshold modulation parameter set are contained in a hybrid modulation program.-
公开(公告)号：EP3102283B1
公开(公告)日：2018-02-28
申请号：EP15702346.6
申请日：2015-01-21
CPC分类号： A61N1/36164 , A61N1/0551 , A61N1/36071 , A61N1/36125 , A61N1/36132 , A61N1/3615 , A61N1/37247
摘要： A neuromodulation system configured for providing sub-threshold neuromodulation therapy to a patient. The neuromodulation system comprises a neuromodulation lead having at least one electrode configured for being implanted along a spinal cord of a patient, a plurality of electrical terminals configured for being respectively coupled to the at least one electrode, modulation output circuitry configured for delivering sub-threshold modulation energy to active ones of the at least one electrode, and control/processing circuitry configured for selecting a percentage from a plurality of percentages based on a known longitudinal location of the neuromodulation lead relative to the spinal cord, computing an amplitude value as a function of the selected percentage, and controlling the modulation output circuitry to deliver sub-threshold modulation energy to the patient at the computed amplitude value.
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4.发明授权Stimulation system to control neural recruitment order and clinical effect 有权刺激系统zum Steuern der neuralen Rekrutierungsreihenfolge und klinischen Wirkung
公开(公告)号：EP2586490B1
公开(公告)日：2016-02-24
申请号：EP12199556.7
申请日：2008-07-18
CPC分类号： A61N1/36146 , A61N1/36003 , A61N1/36007 , A61N1/36017 , A61N1/36036 , A61N1/36046 , A61N1/3605 , A61N1/3606 , A61N1/36135 , A61N1/37247 , A61N1/378 , A61N1/3787 , A61N1/3906
摘要： The invention relates to an implantable electrical tissue stimulation system (10), comprising: one or more electrical terminals (58) configured for being coupled to one or more stimulation leads (12); output stimulation circuitry (50) configured for outputting electrical stimulation energy to the one or more electrical terminals (58) in accordance with a defined waveform; monitoring circuitry (70) configured for measuring one or more electrical characteristics of the tissue; and control circuitry (74) configured for modifying a pulse shape of the defined waveform based on the measured one or more electrical characteristics, thereby changing the characteristics of the electrical stimulation energy outputted to the one or more electrical terminals (58).
摘要翻译： 本发明涉及一种可植入电组织刺激系统（10），包括：一个或多个电气端子（58），被配置为耦合到一个或多个刺激引线（12）; 输出刺激电路（50），被配置为根据定义的波形向一个或多个电端子（58）输出电刺激能量; 监测电路（70）被配置为测量所述组织的一个或多个电特性; 以及控制电路（74），其被配置为基于所测量的一个或多个电特性来修改所定义的波形的脉冲形状，从而改变输出到所述一个或多个电端子（58）的电刺激能量的特性。
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5.发明授权Stimulation system to control neural recruitment order and clinical effect 有权刺激系统zum Steuern der neuralen Rekrutierungsreihenfolge und klinische Wirkung
公开(公告)号：EP2586491B1
公开(公告)日：2016-08-17
申请号：EP12199558.3
申请日：2008-07-18
CPC分类号： A61N1/36146 , A61N1/36003 , A61N1/36007 , A61N1/36017 , A61N1/36036 , A61N1/36046 , A61N1/3605 , A61N1/3606 , A61N1/36135 , A61N1/37247 , A61N1/378 , A61N1/3787 , A61N1/3906
摘要： The invention relates to an implantable electrical tissue stimulation system (10), comprising: one or more electrical terminals (58) configured for being coupled to one or more stimulation leads (12); output stimulation circuitry (50) configured for outputting electrical stimulation energy to the one or more electrical terminals (58) in accordance with a defined waveform; monitoring circuitry (70) configured for measuring one or more electrical characteristics of the tissue; and control circuitry (74) configured for modifying a pulse shape of the defined waveform based on the measured one or more electrical characteristics, thereby changing the characteristics of the electrical stimulation energy outputted to the one or more electrical terminals (58).
摘要翻译： 本发明涉及一种可植入电组织刺激系统（10），包括：一个或多个电气端子（58），被配置为耦合到一个或多个刺激引线（12）; 输出刺激电路（50），被配置为根据定义的波形向一个或多个电端子（58）输出电刺激能量; 监测电路（70）被配置为测量所述组织的一个或多个电特性; 以及控制电路（74），其被配置为基于所测量的一个或多个电特性来修改所定义的波形的脉冲形状，从而改变输出到所述一个或多个电端子（58）的电刺激能量的特性。
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