摘要:
Neurostimulation of a mixed nerve comprising a plurality of nerve fibre types. An implantable electrode array comprising a plurality of electrodes is positioned proximal to the mixed nerve. An electrical stimulus is delivered from at least one nominal stimulus electrode of the implantable electrode array, in accordance with a set of stimulus parameters. A recording of the electrophysiological response evoked by the electrical stimulus is obtained from at least one nominal recording electrode of the implantable electrode array. The recording is analysed by assessing one or more selected characteristics of the recording, and from the observed selected characteristics a level of recruitment of one or more fibre types recruited by the electrical stimulus is identified. The stimulus parameters are refined in a manner to effect selective recruitment of one or more fibre types relative to other fibre types of the mixed nerve.
摘要:
A monitoring system has biomechanical sensors, physiological sensors and a controller which receive sensory inputs from the sensors to provide output signals for the output device, and it detects from the sensory inputs risk of a syncopal event The bio-mechanical sensors include sensors arranged to allow the processor to detect a user postures and posture transitions. The processor operates a finite state machine, in which there is a state corresponding to each of a plurality of user physical postures and to each of a plurality of transitions between said postures, and the processor determines a relevant state depending on the sensory inputs. A device output may be muscle stimulation to prevent syncope, and there are stimulation permissions associated with the finite state machine states.
摘要:
Methods and apparatuses for stimulation of the vagus nerve to treat inflammation including adjusting the stimulation based on one or more metric sensitive to patient response. The one or more metrics may include heart rate variability, level of T regulatory cells, particularly memory T regulatory cells, temperature, etc. Stimulation may be provided through an implantable microstimulator.
摘要:
A device comprises an elongated catheter, an expandable balloon associated with the catheter, and a plurality of circumferentially spaced flexible circuits (200) extending longitudinally along a surface of the expandable balloon. The flexible circuits (200) may include a plurality of openings extending through the flexible circuits (200), such openings configured to increase flexibility of the flexible circuits (200).
摘要:
Methods and systems for providing therapy related to urological disorders which relate to stimulation of the saphenous nerve (SAFN) either alone or in combination with the posterior tibial nerve (PTN), medial plantar nerve (MPN) or lateral planar nerve. In embodiments nerves are stimulated by percutaneous, transcutaneous, and/or implanted stimulators. In embodiments the SAFN is stimulated below the level of the knee or near the medial malleolus. Embodiments also disclose improving nerve stimulation, including SAFN stimulation, using systems and methods termed enhanced transcutaneous electrical stimulation (eTENS) since these enhance the excitation of neural tissue. In an embodiment, systems and methods are provided to increase the chance of providing the selective modulation of specific (targeted) neural substrate, while decreasing the risk of activation of adjacent (non-targeted) nervous tissue.
摘要:
The present disclosure relates generally to using detected bladder events for the diagnosis of urinary incontinence or the treatment of lower urinary tract dysfunction. A system includes a sensing device comprising a pressure sensor to directly detect a pressure within a bladder. The sensing device is adapted to be located within the bladder. The system also includes a signal processing device to: receive a signal indicating the detected pressure within the bladder; detect a bladder event based the detected pressure within the signal; and characterize the bladder event as a bladder contraction event or a non-contraction event. The characterization of the bladder event can be used in the diagnosis of urinary incontinence or the treatment of lower urinary tract dysfunction.
摘要:
A cochlear implant sound processor including processor apparatus that, in response to being paired with a cochlear implant, converts audio signals from a microphone into stimulation data and transfer the stimulation data to cochlear implant, and in response to a failure to detect the cochlear implant, transfers the audio signals to a contralateral sound processor. Systems and methods are also disclosed.