-
公开(公告)号：EP2697230B1
公开(公告)日：2016-03-30
申请号：EP11716357.6
申请日：2011-04-14
发明人： WANG, Tao , PENDRI, Annapurna , ZHANG, Zhongxing , ZHAI, Weixu , LI, Guo , GERRITZ, Samuel , SCOLA, Paul, Michael , SUN, Li-Qiang , ZHAO, Qian , MULL, Eric
IPC分类号： C07D487/08 , C07D498/08 , A61K31/53 , A61P31/14
CPC分类号： C07D498/08 , C07D487/08
-
公开(公告)号：EP2614064B8
公开(公告)日：2015-01-14
申请号：EP11758033.2
申请日：2011-09-06
发明人： PENDRI, Annapurna , LI, Guo , GERRITZ, Samuel , LANGLEY, David, R. , TRAINOR, George, L. , MEANWELL, Nicholas, A.
IPC分类号： C07D487/04 , A61K31/519 , A61P31/18
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06 , C07D519/00 , A61K2300/00
-
公开(公告)号：EP2488526A1
公开(公告)日：2012-08-22
申请号：EP10771277.0
申请日：2010-10-14
发明人： WANG, Tao , PENDRI, Annapurna , ZHANG, Zhongxing , ZHAI, Weixu , LI, Guo , GERRITZ, Samuel , SCOLA, Paul Michael , SUN, Li-Qiang , ZHAO, Qian , MULL, Eric
IPC分类号： C07D487/08 , C07D498/08 , A61K31/53
CPC分类号： C07D487/08 , C07D498/08
摘要： The disclosure provides compounds of formula (I), including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
摘要翻译： 本公开提供了式（I）的化合物，包括药学上可接受的盐，以及使用该化合物的组合物和方法。 该化合物对丙型肝炎病毒（HCV）具有活性，并可用于治疗感染HCV的患者。
-
4.发明授权FUSED PYRIMIDINES AS INHIBITORS OF IMMUNODEFICIENCY VIRUS REPLICATION 有权简明嘧啶，其IMMUNDEFIZIENZVIRUSREPLIKATION抑制剂的
公开(公告)号：EP2822949B1
公开(公告)日：2016-09-07
申请号：EP13710240.6
申请日：2013-03-04
发明人： PENDRI, Annapurna , LANGLEY, David R. , GERRITZ, Samuel , LI, Guo , ZHAI, Weixu , D'ANDREA, Stanley , PATEL, Manoj , NAIDU, B. Narasimhulu , PEESE, Kevin , WANG, Zhongyu
IPC分类号： C07D487/04 , A61P31/18 , A61K31/519
CPC分类号： C07D487/04 , C07D498/08 , C07D519/00
-
公开(公告)号：EP1670460B1
公开(公告)日：2014-11-26
申请号：EP04794436.8
申请日：2004-10-06
IPC分类号： A61K31/415 , C07D231/10
CPC分类号： C04B35/632 , C07D231/14 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D405/10 , C07D405/12 , C07D405/14 , C07D409/10 , C07D413/10
-
公开(公告)号：EP2697230A1
公开(公告)日：2014-02-19
申请号：EP11716357.6
申请日：2011-04-14
发明人： WANG, Tao , PENDRI, Annapurna , ZHANG, Zhongxing , ZHAI, Weixu , LI, Guo , GERRITZ, Samuel , SCOLA, Paul, Michael , SUN, Li-Qiang , ZHAO, Qian , MULL, Eric
IPC分类号： C07D487/08 , C07D498/08 , A61K31/53 , A61P31/14
CPC分类号： C07D498/08 , C07D487/08
摘要： The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
-
公开(公告)号：EP1644335A1
公开(公告)日：2006-04-12
申请号：EP04778086.1
申请日：2004-07-12
发明人： SUN, Chong-Qing , SITKOFF, Doree , EWING, William, R. , HUANG, Yanting , ELLSWORTH, Bruce, A. , SULSKY, Richard, B. , GU, Zhengxiang , MURUGESAN, Natesan , GERRITZ, Samuel , PENDRI, Annapurna
IPC分类号： C07D215/38 , A61K31/47
CPC分类号： C07D417/06 , C07D215/38 , C07D215/48 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/06 , C07D409/04 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12
摘要： The invention provides for compounds of formula (I); wherein the substitutents are as described herein. Further provided are methods of using such compounds for the treatment of eating disorders, metabolic disorders, obesity, cognitive disorders, neurological disorders, pain disorders, inflammation disorders, in the promotion of smoking cessation and for the treatment of other psychiatric disorders Also provided are pharmaceutical compositions containing such compounds and pharmaceutical combinations of the compounds of the invention with other therapeutic agents.
-
公开(公告)号：EP2614052B1
公开(公告)日：2014-12-31
申请号：EP11758034.0
申请日：2011-09-06
发明人： CIANCI, Christopher, W. , GERRITZ, Samuel , LI, Guo , PEARCE, Bradley, C. , PENDRI, Annapurna , SHI, Shuhao , ZHAI, Weixu , ZHU, Shirong
IPC分类号： C07D231/14 , C07D233/90 , C07D249/06 , C07D261/18 , C07D403/12 , C07D413/12 , C07D417/12 , C07D207/327 , A61P31/16
CPC分类号： C07D261/18 , C07D207/327 , C07D231/14 , C07D233/90 , C07D249/06 , C07D403/12 , C07D413/12 , C07D417/12
-
公开(公告)号：EP2614064A1
公开(公告)日：2013-07-17
申请号：EP11758033.2
申请日：2011-09-06
发明人： PENDRI, Annapurna , LI, Guo , GERRITZ, Samuel , LANGLEY, David, R. , TRAINOR, George, L. , MEANWELL, Nicholas, A.
IPC分类号： C07D487/04 , A61K31/519 , A61P31/18
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06 , C07D519/00 , A61K2300/00
摘要： The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
-
公开(公告)号：EP1697371B1
公开(公告)日：2007-04-25
申请号：EP04815007.2
申请日：2004-12-17
发明人： GU, Guixue , EWING, William, R. , MIKKILINENI, Amarendra, B. , PENDRI, Annapurna , ELLSWORTH, Bruce, A. , SHER, Philip, M. , GERRITZ, Samuel , SUN, Chongqing , MURUGESAN, Natesan , WU, Ximao
IPC分类号： C07D487/04 , A61K31/5025 , A61P37/02 , A61P25/16
CPC分类号： C07D487/04
摘要： The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the general Formula I. including all prodrugs, pharmaceutically acceptable salts and stereoisomers, R1, R2, R3, R4, R5, m and n are described herein.
摘要翻译： 本申请描述了根据式I的化合物，包含至少一种根据式I的化合物和任选的一种或多种另外的治疗剂的药物组合物以及使用式I化合物单独治疗并且与一种或多种另外的 治疗剂。 所述化合物具有通式I，包括所有前药，药学上可接受的盐和立体异构体，R 1，R 2，R 3，R 4，R 5，m和n如本文所述。
-
-
-
-
-
-
-
-
-
搜索结果
20 条记录 (耗时 0.019 秒)
