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公开(公告)号：EP2970297A1
公开(公告)日：2016-01-20
申请号：EP14715481.9
申请日：2014-03-07
IPC分类号： C07D487/04 , A61K31/519 , A61K31/5383 , C07D487/16 , C07D498/16 , C07D498/22 , A61P31/18
CPC分类号： C07D498/22 , A61K31/519 , A61K31/529 , A61K31/5383 , A61K31/5386 , A61K45/06 , C07D471/22 , C07D487/04 , C07D487/16 , C07D498/16 , C07D498/18 , A61K2300/00
摘要： The disclosure generally relates to compounds of formula (I), including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
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2.发明公开PYRAZOLOPYRIMIDINE MACROCYCLES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION 审中-公开吡唑并嘧啶 - 咪唑啉酮抑制剂替代物
公开(公告)号：EP3107917A1
公开(公告)日：2016-12-28
申请号：EP14709808.1
申请日：2014-02-19
发明人： NAIDU, B. Narasimhulu , PATEL, Manoj , D'ANDREA, Stanley , ZHENG, Zhizhen Barbara , CONNOLLY, Timothy P. , LANGLEY, David R. , PEESE, Kevin , WANG, Zhongyu , WALKER, Michael A. , KADOW, John F.
IPC分类号： C07D498/16 , A61K31/519 , A61P31/18
CPC分类号： C07D498/22 , A61K31/519 , A61K45/06 , C07D498/16
摘要： The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
摘要翻译： 本发明一般涉及式I化合物，包括用于治疗人类免疫缺陷病毒（HIV）感染的组合物和方法。 本公开提供了HIV的新型抑制剂，含有这些化合物的药物组合物，以及使用这些化合物治疗HIV感染的方法。
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公开(公告)号：EP2822950B1
公开(公告)日：2016-10-19
申请号：EP13710940.1
申请日：2013-03-04
IPC分类号： C07D487/04 , A61K31/519 , A61P31/18
CPC分类号： C07D487/04 , A61K31/519 , A61K31/695 , A61K45/06 , C07F7/0812
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公开(公告)号：EP2089385B1
公开(公告)日：2016-01-06
申请号：EP07863696.6
申请日：2007-10-31
IPC分类号： C07K5/083
CPC分类号： C07K5/0804
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公开(公告)号：EP2086967A2
公开(公告)日：2009-08-12
申请号：EP07863701.4
申请日：2007-10-31
IPC分类号： C07D409/04 , C07D231/56 , C07D237/32 , C07D239/88 , C07D487/04 , C07D495/04 , C07D498/04 , C07K5/08
CPC分类号： C07K5/0804 , A61K31/7056 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K38/212 , A61K45/06 , A61K47/60 , C07D487/04 , C07D513/04 , C07K5/0808 , A61K2300/00
摘要： Macrocyclic peptides are disclosed having the general formula (I) wherein R3, R3', R4, R6, R', X, Q and W are described. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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6.发明授权FUSED PYRIMIDINES AS INHIBITORS OF IMMUNODEFICIENCY VIRUS REPLICATION 有权简明嘧啶，其IMMUNDEFIZIENZVIRUSREPLIKATION抑制剂的
公开(公告)号：EP2822949B1
公开(公告)日：2016-09-07
申请号：EP13710240.6
申请日：2013-03-04
发明人： PENDRI, Annapurna , LANGLEY, David R. , GERRITZ, Samuel , LI, Guo , ZHAI, Weixu , D'ANDREA, Stanley , PATEL, Manoj , NAIDU, B. Narasimhulu , PEESE, Kevin , WANG, Zhongyu
IPC分类号： C07D487/04 , A61P31/18 , A61K31/519
CPC分类号： C07D487/04 , C07D498/08 , C07D519/00
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公开(公告)号：EP2768831B1
公开(公告)日：2015-11-25
申请号：EP12783457.0
申请日：2012-10-17
IPC分类号： C07D487/04 , A61K31/55 , A61P31/14
CPC分类号： C07D487/04
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公开(公告)号：EP2822950A1
公开(公告)日：2015-01-14
申请号：EP13710940.1
申请日：2013-03-04
IPC分类号： C07D487/04 , A61K31/519 , A61P31/18
CPC分类号： C07D487/04 , A61K31/519 , A61K31/695 , A61K45/06 , C07F7/0812
摘要： The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection. (i)
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公开(公告)号：EP2089020A1
公开(公告)日：2009-08-19
申请号：EP07864430.9
申请日：2007-11-15
发明人： WANG, Alan Xiangdong , ZHENG, Barbara Zhizhen , D'ANDREA, Stanley , MEANWELL, Nicholas A. , SCOLA, Paul Michael
IPC分类号： A61K31/407 , C07D487/04 , C07D498/04 , A61P31/12
CPC分类号： C07D498/04 , C07D487/04 , C07K5/0802 , C07K5/0815
摘要： Macrocyclic peptides having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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公开(公告)号：EP1629000B1
公开(公告)日：2009-02-18
申请号：EP04759941.0
申请日：2004-04-16
发明人： MCPHEE, Fiona , CAMPBELL, Jeffrey Allen , LI, Wenying , D'ANDREA, Stanley , ZHENG, Zhizhen Barbara , GOOD, Andrew Charles , CARINI, David J. , JOHNSON, Barry L. , SCOLA, Paul Michael , BOY, Kenneth, M.
CPC分类号： C07K5/0804 , A61K38/00 , C12P7/62 , C12P13/04 , C12P41/005
摘要： Macrocyclic isoquinoline are disclosed having the general formula: A compound of formula 1: wherein R1 to R9, Q and W are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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