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公开(公告)号：EP0988302A1
公开(公告)日：2000-03-29
申请号：EP98930737.6
申请日：1998-05-27
发明人： GUTTERER, Beate , ULRICH, Wolf-Rüdiger , AMSCHLER, Hermann , BEUME, Rolf , HÄFNER, Dietrich , BÄR, Thomas , MARTIN, Thomas , KILIAN, Ulrich , ELTZE, Manfrid , BRAND, Ursula , BOSS, Hildegard , KLEY, Hans-Peter , SCHUDT, Christian , GOEBEL, Karl-Josef , FLOCKERZI, Dieter , HATZELMANN, Armin
IPC分类号： C07D471/04 , A61K31/47
CPC分类号： C07D471/04
摘要： The invention concerns the compounds 8,9-Diethoxy-2-methyl-6- [4(p-toluenesulfonamido)phenyl] -1,2,3,4,4a,10b-hexahydrobenzo[c] [1,6]naphthyridine and 9-Ethoxy-8-methoxy-2- methyl-6-[4-(p-toluenesulfonamido) phenyl]-1,2,3,4,4a,10b-hexahydrobenzo [c][1,6]naphthyridine and their therapeutic application.
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公开(公告)号：EP0796251A1
公开(公告)日：1997-09-24
申请号：EP95941683.0
申请日：1995-12-07
发明人： BOER, Rainer , BOSS, Hildegard , ELTZE, Manfrid , BELLER, Klaus-Dieter , SANDERS, Karl , BRAND, Ursula , PRÜSSE, Wolfgang , ULRICH, Wolf-Rüdiger
CPC分类号： C07D239/545 , C07D239/557 , C07D239/60 , C07D285/16
摘要： Disclosed are compounds of formula I, in which the substituents and symbols have the meanings indicated in the description. These compounds are novel 5-HT1A-agonists and α1-adrenoceptor blockers.
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公开(公告)号：EP0796251B1
公开(公告)日：2001-10-17
申请号：EP95941683.5
申请日：1995-12-07
发明人： BOER, Rainer , BOSS, Hildegard , ELTZE, Manfrid , BELLER, Klaus-Dieter , SANDERS, Karl , BRAND, Ursula , PRÜSSE, Wolfgang , ULRICH, Wolf-Rüdiger
IPC分类号： C07D239/54 , C07D239/60 , C07D285/16 , A61K31/505
CPC分类号： C07D239/545 , C07D239/557 , C07D239/60 , C07D285/16
摘要： Disclosed are compounds of formula I, in which the substituents and symbols have the meanings indicated in the description. These compounds are novel 5-HT1A-agonists and α1-adrenoceptor blockers.
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