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1.发明授权METHOD AND APPARATUS FOR DIFFUSIVE TRANSFER BETWEEN IMMISCIBLE FLUIDS 失效方法和VORICHTUNG FOR之间不相溶的液体扩散
公开(公告)号：EP0790849B1
公开(公告)日：2003-03-26
申请号：EP95934715.4
申请日：1995-10-20
发明人： HOLMES, Robert, George, Godfrey , BULL, Adrian, James , SIMPER, Adrian, Mark , SHAW, John, Edward, Andrew , BRENNAN, David, Edward , TURNER, Robert, Edward , SIMPSON, Richard, Iain , WESTWOOD, Lyn
CPC分类号： G01N1/4005 , B01D11/04 , B01D11/0403 , B01D11/0407 , B01D11/0415 , B01D11/0419 , B01D11/0426 , B01D11/0496 , B01D61/246 , B01D61/28 , B01F13/0059 , B01F13/0093 , B01F2005/0031 , B01J19/0093 , B01J2219/00783 , B01J2219/00822 , B01J2219/00828 , B01J2219/00831 , B01J2219/00833 , B01J2219/00837 , B01J2219/00995 , G01N25/14 , G01N27/44743 , G01N30/6069 , G01N30/6095 , G01N2001/4016
摘要： In order to facilitate diffusive transfer of an entity such as a solute between immiscible fluids and subsequent separation of the fluids without mixing, method and apparatus are disclosed having first and second fluid flow paths (11, 12) carrying first and second immiscible fluids, the flow paths communicating with one another in an interface region (16) in which the fluids contact one another and a stable open interface is formed. Diffusive transfer takes place across the interface, and subsequently the fluids flow away from the interface without mixing. The width of the flow paths in the interface region measured normal to the interface lies between 10 and 500 micrometres.
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2.发明公开
公开(公告)号：EP1098709A1
公开(公告)日：2001-05-16
申请号：EP99937891.2
申请日：1999-03-02
IPC分类号： B01L3/00
CPC分类号： B01L3/502738 , B01L3/50273 , B01L3/502746 , B01L2200/10 , B01L2300/0816 , B01L2300/087 , B01L2400/0406 , B01L2400/0487 , B01L2400/0655 , B01L2400/0677 , B01L2400/082
摘要： An apparatus for varying the rate of flow of a fluid in a pathway by the use of deformable valves and clamps which change their size, position, state or function on application of heat and/or pressure is described. A disposable chemical assay device (10), and a method of using the device incorporating the apparatus are also described. The assay device (10) includes an inlet port (12), a reaction chamber (14), a waste depot (16), a filter chamber (18), a processing chamber (20), wash solution/reagent reservoirs (22 and 24), an array of metered readout cells (26, 28, 30, and 32), and breather tubes (11 and 13). The invention, in a preferred embodiment, offers an advantage over existing assay devices because the condition or state of the deformable valves and clamps may be changed. Therefore more complex operations and procedures may be performed by the assay device (10) than has been previously achievable.
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公开(公告)号：EP0910446A1
公开(公告)日：1999-04-28
申请号：EP97916564.0
申请日：1997-04-15
CPC分类号： G01N1/34 , B01D11/0415 , B01D11/0419 , B01D11/0426 , B01D61/24 , B01D61/28 , B01F13/0059 , B01F13/0093 , B01F2005/0031 , B01J19/0093 , B01J2219/00828 , B01J2219/00831 , B01J2219/00844 , G01N2001/4061
摘要： Apparatus for carrying out a process between first and second immiscible fluids, comprises first and second channels defining flow paths, for permitting fluid flow of respective first and second immiscible fluids therethrough. Portions of the flow paths are disposed close to, or adjacent to, one another and communicate with one another to define a region in which, in use, a stable interface between the fluids is formed. One, or more, dimensions of the region are varied along the length of the interface in a direction of fluid flow to compensate for variation in the properties of the fluids during the carrying out of the process and thereby maintain stability of the interface.
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公开(公告)号：EP0787029B1
公开(公告)日：1999-01-07
申请号：EP95934714.7
申请日：1995-10-20
发明人： SHAW, John, Edward, Andrew , SIMPSON, Richard, Iain , BULL, Adrian, James , SIMPER, Adrian, Mark , HOLMES, Robert, George, Godfrey
CPC分类号： G01N1/4005 , B01D11/0403 , B01D11/0407 , B01D11/0415 , B01D11/0419 , B01D11/0426 , B01D11/043 , B01D11/0453 , B01D11/0496 , B01D61/246 , B01D61/28 , B01F13/0059 , B01F13/0093 , B01F2005/0031 , B01J19/0093 , B01J2219/00783 , B01J2219/00828 , B01J2219/00833 , B01J2219/00844 , B01J2219/00853 , B01J2219/00907 , B01J2219/00995 , G01N1/34 , G01N25/14 , G01N27/44743 , G01N30/6069 , G01N30/6095 , G01N2001/4016
摘要： PCT No. PCT/GB95/02488 Sec. 371 Date Sep. 16, 1997 Sec. 102(e) Date Sep. 16, 1997 PCT Filed Oct. 20, 1995 PCT Pub. No. WO96/12540 PCT Pub. Date May 2, 1996In order to facilitate diffusive transfer of an entity such as a solute between immiscible fluids and subsequent separation of the liquids without mixing, a method and an apparatus are disclosed and have first and second flow paths carrying first and second immiscible fluids on opposite sides of a foraminous sheet. The height of the apertures in the sheet is not greater than 200 micrometers (measured perpendicular to the width of the sheet and to the direction of fluid flow), and a stable interface is formed between the fluids within each aperture with a significant amount of fluid flow immediately adjacent the interface. Diffusive transfer takes place across the interface, and subsequently the fluids flow away from the region without mixing. The width of the flow paths measured perpendicular to sheet lies between 10 and 500 micrometers. The walls of each aperture may be parallel or tapered.
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公开(公告)号：EP0787029A1
公开(公告)日：1997-08-06
申请号：EP95934714.0
申请日：1995-10-20
发明人： SHAW, John, Edward, Andrew , SIMPSON, Richard, Iain , BULL, Adrian, James , SIMPER, Adrian, Mark , HOLMES, Robert, George, Godfrey
CPC分类号： G01N1/4005 , B01D11/0403 , B01D11/0407 , B01D11/0415 , B01D11/0419 , B01D11/0426 , B01D11/043 , B01D11/0453 , B01D11/0496 , B01D61/246 , B01D61/28 , B01F13/0059 , B01F13/0093 , B01F2005/0031 , B01J19/0093 , B01J2219/00783 , B01J2219/00828 , B01J2219/00833 , B01J2219/00844 , B01J2219/00853 , B01J2219/00907 , B01J2219/00995 , G01N1/34 , G01N25/14 , G01N27/44743 , G01N30/6069 , G01N30/6095 , G01N2001/4016
摘要： PCT No. PCT/GB95/02488 Sec. 371 Date Sep. 16, 1997 Sec. 102(e) Date Sep. 16, 1997 PCT Filed Oct. 20, 1995 PCT Pub. No. WO96/12540 PCT Pub. Date May 2, 1996In order to facilitate diffusive transfer of an entity such as a solute between immiscible fluids and subsequent separation of the liquids without mixing, a method and an apparatus are disclosed and have first and second flow paths carrying first and second immiscible fluids on opposite sides of a foraminous sheet. The height of the apertures in the sheet is not greater than 200 micrometers (measured perpendicular to the width of the sheet and to the direction of fluid flow), and a stable interface is formed between the fluids within each aperture with a significant amount of fluid flow immediately adjacent the interface. Diffusive transfer takes place across the interface, and subsequently the fluids flow away from the region without mixing. The width of the flow paths measured perpendicular to sheet lies between 10 and 500 micrometers. The walls of each aperture may be parallel or tapered.
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公开(公告)号：EP1054734B1
公开(公告)日：2003-07-23
申请号：EP99901739.5
申请日：1999-01-18
IPC分类号： B01L3/02
CPC分类号： B01L3/0268 , B01J19/0046 , B01J2219/00315 , B01J2219/00317 , B01J2219/00351 , B01J2219/00367 , C40B60/14 , G01N35/1065 , G01N2035/1034 , G01N2035/1044
摘要： Apparatus for dispensing a predetermined volume of a liquid (18) comprises a reservoir (12) for the liquid, a channel (13) provided with an outlet (16) for conveying the liquid (18) from the reservoir to the outlet, and means for generating a pulse of gas. The apparatus is arranged such that the flow of gas causes a predetermined volume of liquid to be ejected from the outlet. The outlet comprises a pair of openings in the channel which face one another, the liquid being retained between the openings by surface tension in the absence of a flow of gas. The gas flow is directed towards one of said openings in use. The apparatus may be used to dispense volumes of a liquid reagent in the range 1 nl to 2νl. The apparatus avoids contamination of the liquid, and dispensing head construction allows devices to be low cost disposable units. The apparatus is less sensitive to liquid viscosity than existing devices.
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公开(公告)号：EP1031031A1
公开(公告)日：2000-08-30
申请号：EP98952897.1
申请日：1998-11-10
IPC分类号： G01N27/416
CPC分类号： G01N27/4045
摘要： A gas sensor is described which is particularly well suited as a carbon monoxide (CO) sensor in a self test gas sensor. The sensor includes a number of aspects which may or may not be used in conjunction with one another. A first aspect is an embodiment which reduces electrical interference (or cross-talk) between a test or gas generating cell and a sensing cell. In one embodiment baffles are provided to prevent cross-talk. In another embodiment a switching circuit ensures that a test gas generator is operational only when the gas sensor is disconnected from a current source. A second aspect is an embodiment which includes an improved wick which is in close proximity with an electrode and ensures that the electrolyte is always in contact with the electrode. In an alternate embodiment a solid polymer electrolyte is used between the electrodes. A third aspect is an improved catalyst which reduces the reaction energy and thereby renders the sensor more sensitive. The catalyst is also cheaper than platinum. Overall the gas sensor uses less components than existing gas sensors and is therefore cheaper and easier to assemble and more reliable.
摘要翻译： 描述了气体传感器，其特别适合作为自测气体传感器中的一氧化碳（CO）传感器。 传感器包括许多可以或不可以彼此结合使用的方面。 第一方面是减少测试或气体生成单元与感测单元之间的电干扰（或串扰）的实施例。 在一个实施例中，提供挡板以防止串扰。 在另一个实施例中，开关电路确保只有当气体传感器从电流源断开时测试气体发生器才可操作。 第二方面是一个实施例，其包括与电极非常接近并且确保电解质始终与电极接触的改进芯。 在一个替代实施例中，在电极之间使用固体聚合物电解质。 第三方面是一种改进的催化剂，其降低反应能量并由此使传感器更敏感。 催化剂也比铂更便宜。 总体而言，气体传感器比现有的气体传感器使用更少的部件，因此更便宜且更容易组装并且更可靠。
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8.发明公开METHOD AND APPARATUS FOR DIFFUSIVE TRANSFER BETWEEN IMMISCIBLE FLUIDS 失效方法和VORICHTUNG FOR之间不相溶的液体扩散
公开(公告)号：EP0790849A1
公开(公告)日：1997-08-27
申请号：EP95934715.0
申请日：1995-10-20
发明人： HOLMES, Robert, George, Godfrey , BULL, Adrian, James , SIMPER, Adrian, Mark , SHAW, John, Edward, Andrew , BRENNAN, David, Edward , TURNER, Robert, Edward , SIMPSON, Richard, Iain , WESTWOOD, Lyn
CPC分类号： G01N1/4005 , B01D11/04 , B01D11/0403 , B01D11/0407 , B01D11/0415 , B01D11/0419 , B01D11/0426 , B01D11/0496 , B01D61/246 , B01D61/28 , B01F13/0059 , B01F13/0093 , B01F2005/0031 , B01J19/0093 , B01J2219/00783 , B01J2219/00822 , B01J2219/00828 , B01J2219/00831 , B01J2219/00833 , B01J2219/00837 , B01J2219/00995 , G01N25/14 , G01N27/44743 , G01N30/6069 , G01N30/6095 , G01N2001/4016
摘要： In order to facilitate diffusive transfer of an entity such as a solute between immiscible fluids and subsequent separation of the fluids without mixing, method and apparatus are disclosed having first and second fluid flow paths (11, 12) carrying first and second immiscible fluids, the flow paths communicating with one another in an interface region (16) in which the fluids contact one another and a stable open interface is formed. Diffusive transfer takes place across the interface, and subsequently the fluids flow away from the interface without mixing. The width of the flow paths in the interface region measured normal to the interface lies between 10 and 500 micrometres.
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公开(公告)号：EP1054734A1
公开(公告)日：2000-11-29
申请号：EP99901739.5
申请日：1999-01-18
IPC分类号： B01L3/02
CPC分类号： B01L3/0268 , B01J19/0046 , B01J2219/00315 , B01J2219/00317 , B01J2219/00351 , B01J2219/00367 , C40B60/14 , G01N35/1065 , G01N2035/1034 , G01N2035/1044
摘要： Apparatus for dispensing a predetermined volume of a liquid (18) comprises a reservoir (12) for the liquid, a channel (13) provided with an outlet (16) for conveying the liquid (18) from the reservoir to the outlet, and means for generating a pulse of gas. The apparatus is arranged such that the flow of gas causes a predetermined volume of liquid to be ejected from the outlet. The outlet comprises a pair of openings in the channel which face one another, the liquid being retained between the openings by surface tension in the absence of a flow of gas. The gas flow is directed towards one of said openings in use. The apparatus may be used to dispense volumes of a liquid reagent in the range 1 nl to 2νl. The apparatus avoids contamination of the liquid, and dispensing head construction allows devices to be low cost disposable units. The apparatus is less sensitive to liquid viscosity than existing devices.
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