-
公开(公告)号：EP1661882B1
公开(公告)日：2013-10-30
申请号：EP04747271.7
申请日：2004-07-09
发明人： SUDOH, Masayuki , TSUKUDA, Takuo , MASUBUCHI, Miyako , KAWASAKI, Kenichi , MURATA, Takeshi , WATANABE, Fumio , FUKUDA, Hiroshi , KOMIYAMA, Susumu , HAYASE, Tadakatsu
IPC分类号： C07C231/02 , C07C69/738 , C07C235/76 , C07D303/12 , C07D317/18 , A61K31/195 , A61K31/201 , A61K31/216 , A61K31/405 , A61P31/12
CPC分类号： A61K31/195 , A61K31/216 , A61K31/405 , C07C235/76
-
公开(公告)号：EP2119718B1
公开(公告)日：2012-04-11
申请号：EP08721047.2
申请日：2008-02-29
发明人： SHIMMA, Nobuo , TSUKUDA, Takuo , KOYANO, Hiroshi , SUDA, Atsushi , HAYASE, Tadakatsu , HADA, Kihito , KAWASAKI, Ken-ichi , KOMIYAMA, Susumu , ONO, Naomi , YAMAZAKI, Toshikazu , SAITOH, Ryoichi , KOHCHI, Masami , HASEGAWA, Kiyoshi
IPC分类号： C07D497/08 , A61K31/529 , A61K31/53 , A61K31/5377 , A61P1/16 , A61P9/10 , A61P11/00 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/02 , A61P21/00 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/06
CPC分类号： C07D497/08 , C07D513/08 , C07D513/18 , C07D513/20
摘要： Disclosed is a new class of compound which has HSP90 inhibitory activity and is useful as an antitumor agent or the like. Also disclosed is a compound which is useful as a synthesis intermediate for the compound having HSP90 inhibitory activity. Specifically disclosed is a compound represented by the general formula (1) below, or a pharmaceutically acceptable salt thereof. (In the formula, X, R1, R2, R3, R4, R5, R6, R7, L1, L2 and L3 are as defined in the description.)
-
3.发明公开ORALLY ADMINISTRABLE VIRIDIOFUNGIN DERIVATIVE HAVING ANTI-HCV ACTIVITY 审中-公开口服VERABREICHBARES VIRIDIOFININDERIVAT MIT ANTI-HCV-AKTIVITÄT
公开(公告)号：EP2886530A1
公开(公告)日：2015-06-24
申请号：EP13829884.9
申请日：2013-08-16
IPC分类号： C07C235/28 , A61K31/192 , A61K31/357 , A61P1/16 , A61P31/14 , A61P43/00 , C07D317/40
CPC分类号： C07D317/36 , A61K31/192 , A61K31/357 , C07C235/28 , C07C235/74 , C07C2601/16 , C07D293/06 , C07D317/34 , C07D317/40
摘要： An object of the present invention is to provide a compound that is useful as an orally available anti-HCV agent. The present invention relates to a compound represented by formula (1) or a pharmaceutically acceptable salt thereof. This compound has an anti-HCV activity and is useful as a medicine.
摘要翻译： 本发明的目的是提供可用作口服抗HCV剂的化合物。 本发明涉及由式（1）表示的化合物或其药学上可接受的盐。 该化合物具有抗HCV活性，可用作药物。
-
公开(公告)号：EP2036895B1
公开(公告)日：2013-01-16
申请号：EP07744100.4
申请日：2007-05-25
发明人： TSUKUDA, Takuo , KAWASAKI, Ken-ichi , KOMIYAMA, Susumu , ISSHIKI, Yoshiaki , SHIRATORI, Yasuhiko , HASEGAWA, Kiyoshi , FUKAMI, Takaaki , MIURA, Takaaki , ONO, Naomi , YAMAZAKI, Toshikazu , NA, Young-Jun , YOON, Dong-Oh , KIM, Sung-Jin
IPC分类号： C07D239/47 , A61K31/505 , A61K31/506 , A61K31/53 , A61K31/5377 , A61P1/16 , A61P3/04 , A61P9/10 , A61P11/00 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/02 , A61P21/00 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/00 , A61P35/00 , A61P35/02 , A61P35/04
CPC分类号： C07D251/16 , C07D239/47 , C07D239/48 , C07D401/12 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/14 , C07D409/04 , C07D413/14 , C07D417/12 , C07D417/14
-
公开(公告)号：EP2119718A1
公开(公告)日：2009-11-18
申请号：EP08721047.2
申请日：2008-02-29
发明人： SHIMMA, Nobuo , TSUKUDA, Takuo , KOYANO, Hiroshi , SUDA, Atsushi , HAYASE, Tadakatsu , HADA, Kihito , KAWASAKI, Ken-ichi , KOMIYAMA, Susumu , ONO, Naomi , YAMAZAKI, Toshikazu , SAITOH, Ryoichi , KOHCHI, Masami , HASEGAWA, Kiyoshi
IPC分类号： C07D497/08 , A61K31/529 , A61K31/53 , A61K31/5377 , A61P1/16 , A61P9/10 , A61P11/00 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/02 , A61P21/00 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/06
CPC分类号： C07D497/08 , C07D513/08 , C07D513/18 , C07D513/20
摘要： The present invention provides a novel class of compounds that have the activity of inhibiting HSP90 enzyme and are useful as anti-cancer agents or such, and compounds that are useful as synthetic intermediates thereof.
Specifically, the present invention provides compounds represented by the following formula (1), and pharmaceutically acceptable salts thereof:
wherein X, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , L 1 , L 2 , and L 3 are as defined in the specification.摘要翻译： 本发明提供了具有抑制HSP90酶的活性的新型化合物，可用作抗癌剂等，以及可用作其合成中间体的化合物。 具体而言，本发明提供下述式（1）表示的化合物及其药学上可接受的盐：其中X，R 1，R 2，R 3，R 4，R 5，R 6，R 7，L 1，L 2和L 3如说明书中所定义。
-
公开(公告)号：EP2036895B9
公开(公告)日：2013-07-10
申请号：EP07744100.4
申请日：2007-05-25
发明人： TSUKUDA, Takuo , KAWASAKI, Ken-ichi , KOMIYAMA, Susumu , ISSHIKI, Yoshiaki , SHIRATORI, Yasuhiko , HASEGAWA, Kiyoshi , FUKAMI, Takaaki , MIURA, Takaaki , ONO, Naomi , YAMAZAKI, Toshikazu , NA, Young-Jun , YOON, Dong-Oh , KIM, Sung-Jin
IPC分类号： C07D239/47 , A61K31/505 , A61K31/506 , A61K31/53 , A61K31/5377 , A61P1/16 , A61P3/04 , A61P9/10 , A61P11/00 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/02 , A61P21/00 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/00 , A61P35/00 , A61P35/02 , A61P35/04
CPC分类号： C07D251/16 , C07D239/47 , C07D239/48 , C07D401/12 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/14 , C07D409/04 , C07D413/14 , C07D417/12 , C07D417/14
-
公开(公告)号：EP2036895A1
公开(公告)日：2009-03-18
申请号：EP07744100.4
申请日：2007-05-25
发明人： TSUKUDA, Takuo , KAWASAKI, Ken-ichi , KOMIYAMA, Susumu , ISSHIKI, Yoshiaki , SHIRATORI, Yasuhiko , HASEGAWA, Kiyoshi , FUKAMI, Takaaki , MIURA, Takaaki , ONO, Naomi , YAMAZAKI, Toshikazu , NA, Young-Jun , YOON, Dong-Oh , KIM, Sung-Jin
IPC分类号： C07D239/47 , A61K31/505 , A61K31/506 , A61K31/53 , A61K31/5377 , A61P1/16 , A61P3/04 , A61P9/10 , A61P11/00 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/02 , A61P21/00 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/00 , A61P35/00 , A61P35/02 , A61P35/04
CPC分类号： C07D251/16 , C07D239/47 , C07D239/48 , C07D401/12 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/14 , C07D409/04 , C07D413/14 , C07D417/12 , C07D417/14
摘要： Compounds represented by formula (1) shown below, pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising such compounds are provided.
摘要翻译： 提供了由下式（1）表示的化合物，其药学上可接受的盐和包含这些化合物的药物组合物。
-
-
-
-
-
-
搜索结果
7 条记录 (耗时 0.031 秒)
