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公开(公告)号：EP1169342A2
公开(公告)日：2002-01-09
申请号：EP00919461.4
申请日：2000-03-17
申请人： CORIXA CORPORATION
IPC分类号： C07K14/35 , C12N15/31 , C12N15/63 , C12N15/11 , G01N33/569 , C12Q1/68 , C07K16/12 , A61K39/04 , C12N5/06 , A61P31/06
CPC分类号： C07K14/35 , A61K35/12 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2035/124 , A61K2039/51 , A61K2039/5154 , C07K2319/00 , C12N2799/021
摘要： Compounds and methods for the diagnosis and treatment of tuberculosis are disclosed. Compounds include the M. tuberculosis antigens Mtb-81 and Mtb-67.2, immunogenic portions thereof and polynucleotides that encode such portions. Such compositions may be used, for example, for the immunotherapy and serodiagnosis of M. tuberculosis infection.
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2.发明公开
公开(公告)号：EP1071451A2
公开(公告)日：2001-01-31
申请号：EP99908169.8
申请日：1999-02-17
申请人： CORIXA CORPORATION
发明人： REED, Steven, G. , SKEIKY, Yasir, A., W. , DILLON, Davin, C. , CAMPOS-NETO, Antonio , HOUGHTON, Raymond , VEDVICK, Thomas, S. , TWARDZIK, Daniel, R. , LODES, Michael, J. , HENDRICKSON, Ronald, C.
CPC分类号： C07K14/35 , A61K38/00 , A61K39/00 , A61K2039/51 , C07K2319/00
摘要： Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.
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公开(公告)号：EP1091749A1
公开(公告)日：2001-04-18
申请号：EP99907065.9
申请日：1999-02-17
申请人： CORIXA CORPORATION
发明人： REED, Steven, G. , SKEIKY, Yasir, A., W. , DILLON, Davin, C. , CAMPOS-NETO, Antonio , HOUGHTON, Raymond , VEDVICK, Thomas, S. , TWARDZIK, Daniel, R. , LODES, Michael, J. , HENDRICKSON, Ronald, C.
CPC分类号： C12Q1/6883 , A61K39/00 , C07K14/35 , C07K16/1289 , C07K2319/00 , C12Q1/689 , G01N33/5695
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