公开(公告)号：EP1696028A2

公开(公告)日：2006-08-30

申请号：EP06005998.7

申请日：2001-05-22

申请人： CORIXA CORPORATION

发明人： Frudakis, Tony ,  Reed, Steven ,  Smith, John ,  Misher, Lynda ,  Dillon, Davin ,  Retter, Marc ,  Wang, Aijun ,  Skeiky, Yasir ,  Harlocker, Susan ,  Day, Craig

IPC分类号： C12N15/12 ,  C12N15/62 ,  C12N5/10 ,  C12Q1/68 ,  C07K14/47 ,  C07K16/18 ,  A61K38/00 ,  G01N33/50

CPC分类号： C07K14/005 ,  A61K35/12 ,  A61K38/00 ,  A61K39/00 ,  A61K48/00 ,  A61K2039/505 ,  A61K2039/5154 ,  A61K2039/53 ,  A61K2039/57 ,  C07K14/47 ,  C07K14/82 ,  C07K2319/00 ,  C12N2740/10022 ,  C12Q1/6886 ,  C12Q2600/158

摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.

摘要翻译： 披露了用于治疗和诊断癌症，特别是乳腺癌的组合物和方法。 说明性组合物包含一种或多种乳房肿瘤多肽，其免疫原性部分，编码此类多肽的多核苷酸，表达此类多肽的抗原呈递细胞和对表达此类多肽的细胞特异的T细胞。 所公开的组合物可用于例如诊断，预防和/或治疗疾病，特别是乳腺癌。

公开(公告)号：EP1696028A3

公开(公告)日：2006-12-27

申请号：EP06005998.7

申请日：2001-05-22

申请人： CORIXA CORPORATION

发明人： Frudakis, Tony ,  Reed, Steven ,  Smith, John ,  Misher, Lynda ,  Dillon, Davin ,  Retter, Marc ,  Wang, Aijun ,  Skeiky, Yasir ,  Harlocker, Susan ,  Day, Craig

IPC分类号： C12N15/12 ,  C12N15/62 ,  C12N5/10 ,  C12Q1/68 ,  C07K14/47 ,  C07K16/18 ,  A61K38/00 ,  G01N33/50

CPC分类号： C07K14/005 ,  A61K35/12 ,  A61K38/00 ,  A61K39/00 ,  A61K48/00 ,  A61K2039/505 ,  A61K2039/5154 ,  A61K2039/53 ,  A61K2039/57 ,  C07K14/47 ,  C07K14/82 ,  C07K2319/00 ,  C12N2740/10022 ,  C12Q1/6886 ,  C12Q2600/158

摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.