-
1.发明公开COMPOSITION FOR LABELING TISSUES OF CENTRAL NERVOUS SYSTEM, METHOD FOR LABELING TISSUES OF CENTRAL NERVOUS SYSTEM, AND SCREENING METHOD USING THE COMPOSITION FOR LABELING TISSUES OF CENTRAL NERVOUS SYSTEM 有权组合物技术组织分类中枢神经系统，方法组织分类中枢神经系统和筛选过程有用于组织分类在中枢神经系统中的组成
公开(公告)号：EP2399612A1
公开(公告)日：2011-12-28
申请号：EP10838989.1
申请日：2010-12-24
发明人： WATANABE, Kohei , SHINTOU, Taichi , NOMOTO, Tsuyoshi , MIYAZAKI, Takeshi , OKANO, Mie , TANAKA, Toshio , NISHIMURA, Yuhei , SHIMADA, Yasuhito
CPC分类号： A61K49/0032 , A61K49/0039 , A61K49/006 , C07D417/06 , G01N33/15 , G01N33/50 , G01N33/58 , G01T1/161
摘要： To provide a central nervous system tissue-labeling composition labeling the central nervous tissue system. Also, another object of the present invention is to provide a method for non-invasively labeling the central nervous tissue system. Further, another object of the present invention is to provide a screening method using the above central nervous system tissue-labeling composition. A central nervous system tissue-labeling composition containing, as an active ingredient, at least one of compounds represented by the general formula (1) or (7).
摘要翻译： 提供一种中枢神经系统组织标记组合物标记所述中枢神经组织系统。因此，本发明的另一个目的是提供一种用于非侵入性标记中枢神经组织系统的方法。此外，本发明的另一个目的是 到提供一种使用上述的中枢神经系统组织标记组合物的筛选方法。 中枢神经系统组织标记组合物含有作为活性成分的，由通式表示的化合物中的至少一种（1）或（7）。
-
2.发明授权TRANSNASAL LABELING COMPOSITION FOR TISSUES OF CENTRAL NERVOUS SYSTEM 有权TRANSNASALE KENNZEICHNUNGSZUSAMMENSETZUNGFÜRGEWEBE DES ZENTRALEN NERVENSYSTEMS
公开(公告)号：EP2517732B1
公开(公告)日：2016-09-21
申请号：EP10838971.9
申请日：2010-12-24
发明人： NOMOTO, Tsuyoshi , WATANABE, Kohei , SHINTOU, Taichi , MIYAZAKI, Takeshi , TANAKA, Toshio , NISHIMURA, Yuhei , SHIMADA, Yasuhito
CPC分类号： A61K49/0004 , A61K49/0032 , A61K49/0041 , A61K51/0446
摘要： There is provided a central nervous system labelling composition for intranasal administration for the purpose of labelling the central nervous system from the olfactory epithelium by way of the olfactory bulb and by means of intranasal administration. Additionally, there is provided a method of non-invasively labelling the central nervous system by way of an administration route that entails little transferability to the entire body. Furthermore, there is provided a screening method using a central nervous system labelling composition for intranasal administration. A central nervous system labelling composition for intranasal administration is characterized by labelling the central nervous system from the olfactory epithelium by way of the olfactory bulb and by means of intranasal administration and by containing at least one compound expressed either by the general formula (1) or the general formula (2) shown below as effective component: and
摘要翻译： 提供了一种用于鼻内给药的中枢神经系统标记组合物，用于通过嗅球通过鼻涕管理从嗅觉上皮标记中枢神经系统的目的。 此外，提供了一种通过对整个身体几乎不具有转移性的施用途径非侵入性地标记中枢神经系统的方法。 此外，提供了使用中枢神经系统标记组合物进行鼻内给药的筛选方法。 用于鼻内给药的中枢神经系统标记组合物的特征在于通过嗅球通过嗅球标记中枢神经系统，并通过鼻内给药并含有至少一种由通式（1）或 通式（2）如下所示为有效成分：和
-
公开(公告)号：EP2849752B1
公开(公告)日：2018-02-21
申请号：EP13849471.1
申请日：2013-10-25
发明人： SHINTOU, Taichi , NOMOTO, Tsuyoshi , WATANABE, Kohei , MIYAZAKI, Takeshi , TANAKA, Toshio , SHIMADA, Yasuhito , NISHIMURA, Yuhei
IPC分类号： A61K31/403 , A61K31/404 , A61K31/423 , A61K31/427 , A61K31/428 , A61K49/00 , A61K41/00 , A61K45/06 , A61P35/00
CPC分类号： A61K31/428 , A61K31/403 , A61K31/404 , A61K31/423 , A61K31/427 , A61K41/0038 , A61K49/0032 , C07D417/06 , C07D417/14
摘要： An object of the present invention is to provide a cancer cell inhibitory drug, particularly a cancer stem-cell inhibitory drug, or a cancer stem-cell detection probe. A cancer cell inhibitory drug containing at least a compound represented by general formula (1).
-
4.发明授权COMPOSITION FOR LABELING TISSUES OF CENTRAL NERVOUS SYSTEM, METHOD FOR LABELING TISSUES OF CENTRAL NERVOUS SYSTEM, AND SCREENING METHOD USING THE COMPOSITION FOR LABELING TISSUES OF CENTRAL NERVOUS SYSTEM 有权用于标记中枢神经系统组织的组合物，用于标记中枢神经系统组织的方法以及使用用于标记中枢神经系统组织的组合物的筛选方法
公开(公告)号：EP2399612B1
公开(公告)日：2018-02-21
申请号：EP10838989.1
申请日：2010-12-24
发明人： WATANABE, Kohei , SHINTOU, Taichi , NOMOTO, Tsuyoshi , MIYAZAKI, Takeshi , OKANO, Mie , TANAKA, Toshio , NISHIMURA, Yuhei , SHIMADA, Yasuhito
CPC分类号： A61K49/0032 , A61K49/0039 , A61K49/006 , C07D417/06 , G01N33/50 , G01N33/58 , G01T1/161
摘要： To provide a central nervous system tissue-labeling composition labeling the central nervous tissue system. Also, another object of the present invention is to provide a method for non-invasively labeling the central nervous tissue system. Further, another object of the present invention is to provide a screening method using the above central nervous system tissue-labeling composition. A central nervous system tissue-labeling composition containing, as an active ingredient, at least one of compounds represented by the general formula (1) or (7).
-
公开(公告)号：EP2849752A1
公开(公告)日：2015-03-25
申请号：EP13849471.1
申请日：2013-10-25
发明人： SHINTOU, Taichi , NOMOTO, Tsuyoshi , WATANABE, Kohei , MIYAZAKI, Takeshi , TANAKA, Toshio , SHIMADA, Yasuhito , NISHIMURA, Yuhei
IPC分类号： A61K31/427 , A61K31/428 , A61K49/00 , A61P35/00
CPC分类号： A61K31/428 , A61K31/403 , A61K31/404 , A61K31/423 , A61K31/427 , A61K41/0038 , A61K49/0032 , C07D417/06 , C07D417/14
摘要： An object of the present invention is to provide a cancer cell inhibitory drug, particularly a cancer stem-cell inhibitory drug, or a cancer stem-cell detection probe.A cancer cell inhibitory drug containing at least a compound represented by general formula (1).
摘要翻译： 本发明的目的在于提供一种癌细胞抑制药，特别是癌干细胞抑制药或癌干细胞检测探针.1。一种癌细胞抑制药，其特征在于，至少含有通式（1）所示的化合物， 。
-
6.发明授权PROBE FOR A BIOLOGICAL SPECIMEN AND LABELLING METHOD AND SCREENING METHOD USING THE PROBE 有权探针 - 生物样品标记方法和筛选方法使用探头
公开(公告)号：EP2370111B1
公开(公告)日：2014-11-05
申请号：EP09835114.1
申请日：2009-12-24
发明人： SHINTOU, Taichi , MIYAZAKI, Takeshi , HIROSE, Masashi , OKUBO, Taketoshi , WATANABE, Kohei , NOMOTO, Tsuyoshi , TANAKA, Toshio , NISHIMURA, Yuhei , SHIMADA, Yasuhito , NISHIMURA, Norihiro
IPC分类号： A61K49/00 , A61K51/00 , C07D401/06 , C07D403/06 , C07D405/06 , C07D409/06 , C07D413/06 , C07D417/06 , C07D417/14 , G01N33/15 , G01N33/50 , C07D209/08 , C07D209/94 , G01N33/58 , G01N33/533 , C07D209/86 , C07D401/08 , C07D403/08 , C07D413/08 , G01N1/30
CPC分类号： A61K51/0453 , A61K49/0002 , A61K49/0008 , A61K49/0021 , A61K49/006 , A61K49/10 , C07D209/08 , C07D209/86 , C07D209/94 , C07D401/08 , C07D403/06 , C07D403/08 , C07D413/08 , C07D417/06 , C07D417/14 , C09B23/0091 , C09B23/04 , C09B23/105 , G01N33/582 , G01N2333/4603 , G01N2500/10
-
7.发明公开LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD 有权标记组合织物眼内，标志着程序对组织及筛选方法人工
公开(公告)号：EP2370110A1
公开(公告)日：2011-10-05
申请号：EP09835113.3
申请日：2009-12-24
发明人： WATANABE, Kohei , SHINTOU, Taichi , NOMOTO, Tsuyoshi , MIYAZAKI, Takeshi , TANAKA, Toshio , NISHIMURA, Yuhei , SHIMADA, Yasuhito , NISHIMURA, Norihiro
IPC分类号： A61K49/00 , C07D403/04 , C07D403/06 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/06 , G01N33/15 , G01N33/50
CPC分类号： A61K49/0021 , A61K49/0002 , A61K49/0039 , A61K49/0041 , A61K49/006 , C07D209/70 , C07D209/96 , C07D215/00 , C07D221/14 , C07D221/18 , C07D263/54 , C07D277/34 , C07D277/36 , C07D277/64 , C07D311/82 , C07D311/86 , C07D405/04 , C07D405/06 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/06 , C07D417/14 , C07D491/052 , C07D491/12 , C07D497/10 , G01N33/5088 , G01N33/582 , G01N2333/4603
摘要： The invention provides a labeling composition for an intraocular tissue of a living individual, which specifically labels the intraocular tissue without need of an invasive operation such as exposure of an ocular tissue or injection of a staining agent into the ocular tissue or a nerve tissue linking to the ocular tissue, a method of noninvasively labeling an intraocular tissue of a living individual, and a screening method using the labeling composition for the intraocular tissues. The composition contains a compound capable of labeling at least a photoreceptor cell layer of a retina, wherein the compound is a staining compound having a particular structure as a partial structure thereof.
-
8.发明授权LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD 有权眼内组织标记组合物，人眼组织标记方法及筛选方法
公开(公告)号：EP2370110B1
公开(公告)日：2017-08-02
申请号：EP09835113.3
申请日：2009-12-24
发明人： WATANABE, Kohei , SHINTOU, Taichi , NOMOTO, Tsuyoshi , MIYAZAKI, Takeshi , TANAKA, Toshio , NISHIMURA, Yuhei , SHIMADA, Yasuhito , NISHIMURA, Norihiro
IPC分类号： A61K49/00 , C07D403/04 , C07D403/06 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/06 , G01N33/15 , G01N33/50
CPC分类号： A61K49/0021 , A61K49/0002 , A61K49/0039 , A61K49/0041 , A61K49/006 , C07D209/70 , C07D209/96 , C07D215/00 , C07D221/14 , C07D221/18 , C07D263/54 , C07D277/34 , C07D277/36 , C07D277/64 , C07D311/82 , C07D311/86 , C07D405/04 , C07D405/06 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/06 , C07D417/14 , C07D491/052 , C07D491/12 , C07D497/10 , G01N33/5088 , G01N33/582 , G01N2333/4603
-
公开(公告)号：EP2849743A1
公开(公告)日：2015-03-25
申请号：EP13849936.3
申请日：2013-10-25
发明人： SHINTOU, Taichi , NOMOTO, Tsuyoshi , WATANABE, Kohei , MIYAZAKI, Takeshi , TANAKA, Toshio , SHIMADA, Yasuhito , NISHIMURA, Yuhei
IPC分类号： A61K31/403 , A61K31/4045 , A61K31/423 , A61K31/428 , A61K31/4709 , A61K49/00 , A61P35/00 , A61P43/00
CPC分类号： A61K31/4709 , A61K31/403 , A61K31/404 , A61K31/423 , A61K31/428 , A61K41/0038 , A61K49/0032 , C09B23/0008 , C09B23/0016 , C09B23/0025 , C09B23/0033 , C09B23/0066 , C09B23/06 , C09B23/083 , C09B23/086 , G01N33/582
摘要： An object of the present invention is to provide a cancer cell inhibitory drug, particularly a cancer stem-cell inhibitory drug, or a cancer stem-cell detection probe. The present invention provides a cancer cell inhibitory drug comprising at least one compound represented by general formula (1) as an active ingredient.
-
10.发明公开
公开(公告)号：EP2517732A1
公开(公告)日：2012-10-31
申请号：EP10838971.9
申请日：2010-12-24
发明人： NOMOTO, Tsuyoshi , WATANABE, Kohei , SHINTOU, Taichi , MIYAZAKI, Takeshi , TANAKA, Toshio , NISHIMURA, Yuhei , SHIMADA, Yasuhito
CPC分类号： A61K49/0004 , A61K49/0032 , A61K49/0041 , A61K51/0446
摘要： There is provided a central nervous system labelling composition for intranasal administration for the purpose of labelling the central nervous system from the olfactory epithelium by way of the olfactory bulb and by means of intranasal administration. Additionally, there is provided a method of non-invasively labelling the central nervous system by way of an administration route that entails little transferability to the entire body. Furthermore, there is provided a screening method using a central nervous system labelling composition for intranasal administration. A central nervous system labelling composition for intranasal administration is characterized by labelling the central nervous system from the olfactory epithelium by way of the olfactory bulb and by means of intranasal administration and by containing at least one compound expressed either by the general formula (1) or the general formula (2) shown below as effective component:
and
-
-
-
-
-
-
-
-
-
搜索结果
11 条记录 (耗时 0.015 秒)
