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公开(公告)号：EP4339288A2
公开(公告)日：2024-03-20
申请号：EP23199693.5
申请日：2017-03-18
申请人： Caris Science, Inc.
IPC分类号： C12N15/115
摘要： Methods and compositions are provided to identify oligonucleotides that bind targets of interest. The targets include tissues, cells, circulating biomarkers such as microvesicles, including those derived from various diseases. The oligonucleotides can be used in diagnostic and therapeutic applications.
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公开(公告)号：EP3268476A1
公开(公告)日：2018-01-17
申请号：EP16762466.7
申请日：2016-03-09
申请人： Caris Science, Inc.
发明人： DOMENYUK, Valeriy , STARK, Adam , XIAO, Nianqing , ZHONG, Zhenyu , MIGLARESE, Mark , SPETZLER, David
IPC分类号： C12N15/115 , C12Q1/68 , C40B20/08
CPC分类号： C12N15/115 , C12N2310/16 , C12N2310/3519 , C12N2320/10 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/156 , C12Q2600/158
摘要： Methods and compositions are provided for oligonucleotide probes and oligonucleotide probe libraries that recognize targets of interest. The targets include circulating biomarkers such as microvesicles, including those derived from various diseases.
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公开(公告)号：EP2935628A1
公开(公告)日：2015-10-28
申请号：EP13865764.8
申请日：2013-12-19
申请人： Caris Science Inc.
IPC分类号： C12Q1/68 , G01N33/566
CPC分类号： G01N33/57488 , C12N15/1048 , C12Q1/6811 , C12Q1/6886 , G01N33/5076 , G01N33/5308 , C12Q2525/205
摘要： Methods are provided for selecting aptamers that are specific to a target of interest from amongst a library of potential aptamer sequences. Aptamers disclosed can be used to detect and/or characterize biological entities of interest, e.g. microvesicles and/or surface antigens. Further disclosed are biomarkers that can be used for diagnosing different disorders including different types of cancer.
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公开(公告)号：EP3464597A1
公开(公告)日：2019-04-10
申请号：EP17803629.9
申请日：2017-05-25
申请人： Caris Science, Inc.
IPC分类号： C12N15/115 , C12Q1/68 , C40B20/02 , C40B20/04 , C40B40/08
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公开(公告)号：EP3601603A1
公开(公告)日：2020-02-05
申请号：EP18775804.0
申请日：2018-03-27
申请人： Caris Science, Inc.
IPC分类号： C12Q1/68 , C12Q1/6809 , C12Q1/6827 , C07H21/04
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公开(公告)号：EP3039174B1
公开(公告)日：2019-10-16
申请号：EP14840036.9
申请日：2014-08-28
申请人： Caris Science, Inc.
IPC分类号： C12Q1/6886 , C12Q1/6883
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公开(公告)号：EP3221452A1
公开(公告)日：2017-09-27
申请号：EP15861137.6
申请日：2015-11-23
申请人： Caris Science, Inc.
IPC分类号： C12N15/113 , C07H21/02
CPC分类号： G01N33/5308 , C12N15/113 , C12N15/115 , C12N2310/113 , C12N2310/16 , C12N2320/10 , C12Q1/34 , C12Q1/6876 , C12Q1/6883 , C12Q1/6886 , C12Q2600/178 , G01N33/564 , G01N33/574 , G01N33/6893 , G01N33/6896 , G01N2333/922
摘要： Methods and compositions are provided to identify oligonucleotide probes that can detect various targets of interest. The targets include microvesicles, microvesicle antigens, and nucleic acids. The target detection may be used to provide a diagnosis, prognosis or theranosis of a medical condition, a disease or a disorder.
摘要翻译： 提供方法和组合物以鉴定可检测各种感兴趣靶标的寡核苷酸探针。 靶标包括微泡，微囊泡抗原和核酸。 目标检测可用于提供医疗状况，疾病或病症的诊断，预后或疾病。
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公开(公告)号：EP4339288A3
公开(公告)日：2024-06-05
申请号：EP23199693.5
申请日：2017-03-18
申请人： Caris Science, Inc.
IPC分类号： C12N15/10 , C12Q1/6811 , C12N15/115
CPC分类号： C12N15/10 , C12Q1/6883 , C12Q1/6886 , C12N2310/1620130101 , C12N2330/3120130101 , C12N15/115 , C12Q2600/10620130101 , C12Q2600/15620130101 , C12Q2600/15820130101 , Y02A50/30 , C12Q1/6811
摘要： Methods and compositions are provided to identify oligonucleotides that bind targets of interest. The targets include tissues, cells, circulating biomarkers such as microvesicles, including those derived from various diseases. The oligonucleotides can be used in diagnostic and therapeutic applications.
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公开(公告)号：EP3828272A1
公开(公告)日：2021-06-02
申请号：EP20213211.4
申请日：2017-03-18
申请人： Caris Science, Inc.
IPC分类号： C12N15/10 , C12Q1/6811 , C12N15/115
摘要： Methods and compositions are provided to identify oligonucleotides that bind targets of interest. The targets include tissues, cells, circulating biomarkers such as microvesicles, including those derived from various diseases. The oligonucleotides can be used in diagnostic and therapeutic applications.
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