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1.发明授权VERFAHREN ZUR HERSTELLUNG VON SPHÄRISCHEN MIKROPARTIKELN MIT GLATTER OBERFLÄCHE, DIE GANZ ODER TEILWEISE AUS MINDESTENS EINEM WASSERUNLÖSLICHEN LINEAREN POLYSACCHARID BESTEHEN 有权工艺生产具有光滑的表面，全部或至少其中的一部分不溶于水的线性多糖EXIST球形微粒
公开(公告)号：EP1124896B1
公开(公告)日：2003-04-02
申请号：EP99944385.6
申请日：1999-08-13
发明人： BENGS, Holger , GRANDE, Jürgen , SCHUTH, Silke , BÖHM, Gitte , SCHNELLER, Arnold , BRUNNER, Anette
CPC分类号： C08J3/14 , C08J2305/00 , C08L3/12 , C08L5/00 , Y10T428/2982 , C08L2666/02
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公开(公告)号：EP1012204B1
公开(公告)日：2003-01-29
申请号：EP98948849.9
申请日：1998-08-20
发明人： BENGS, Holger , GRANDE, Jürgen , SCHNELLER, Arnold , BÖHM, Gitte
CPC分类号： C08J3/14 , A61K9/1652 , C08J2305/00
摘要： The invention relates to microparticles having a uniform spherical shape and showing a very narrow dimensional distribution. These microparticles are fully or partly composed of a linear water insoluble polysaccharide, preferably 1,4-α-D-polyglucan, and they can contain other, preferably biodegradable, polymers and/or active ingredients. They can, inter alia, be used for the controlled release of active ingredients. The are produced by dissolving the 1,4-α-D-polyglucan or said polysaccharide in a solvent, mixing the solution with a precipitating agent, cooling the mixture and separating the formed particles.
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公开(公告)号：EP0815159B1
公开(公告)日：2003-06-04
申请号：EP96905861.9
申请日：1996-03-05
CPC分类号： C08G65/48 , B01D71/52 , C08G61/12 , C08G61/127 , H01M8/1025 , H01M8/1067 , H01M8/1072 , H01M8/1081 , Y02P70/56
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4.发明授权
公开(公告)号：EP0994918B1
公开(公告)日：2002-10-09
申请号：EP98940088.2
申请日：1998-06-26
发明人： BENGS, Holger , SCHNELLER, Arnold , BÖHM, Gitte , SCHUTH, Silke , GRANDE, Jürgen
CPC分类号： C08K5/0016 , C08L3/00 , C08L3/08 , C08L3/10 , C08L2201/06 , C08L2666/02
摘要： The invention relates to homogeneous mixtures which can be processed thermoplastically into biodegradable, physiologically harmless moulded bodies, such as packaging for food or pharmaceutical products, sausage skins and similar. The inventive mixtures contain dialdehyde starch with a degree of oxidation of more than 30 % starch, said dialdehyde starch showing no iodine-starch reaction, and modified starch, water and other plasticisers, and optionally, other biopolymers and additives.
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5.发明公开POLY(ALPHA-1,4-D-GLUCAN) UND DIES ENTHALTENDE THERMOPLASTISCHE POLYMERMISCHUNGEN 审中-公开聚（α-1,4--D-葡聚糖）和该含热塑性聚合物共混物
公开(公告)号：EP1135439A1
公开(公告)日：2001-09-26
申请号：EP99957283.7
申请日：1999-11-05
发明人： BENGS, Holger , SCHNELLER, Arnold , BRUNNER, Anette , TOMKA, Ivan , MÜLLER, Rolf
CPC分类号： A01N25/10 , A61K8/0208 , A61K8/73 , A61K8/732 , A61K8/8135 , A61K8/8147 , A61K8/85 , A61K9/1652 , A61K9/7023 , A61Q19/00 , C08B37/0009
摘要： The invention relates to poly(α-1,4-D-glucan)s with a degree of polymerisation of at least approx. 40, preferably at least approx. 50 and most preferably at least approx. 60. Plasticised poly(α-1,4-D-glucan)s with the aforementioned degrees of polymerisation or thermoplastic polymer mixtures containing plasticised thermoplastic poly(α-1,4-D-glucan)s, are especially suitable as a support matrix for active substances used in agriculture, pharmaceutical active substances and/or cosmetic active substances.
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6.发明公开
公开(公告)号：EP1139980A1
公开(公告)日：2001-10-10
申请号：EP99965416.3
申请日：1999-11-30
发明人： BENGS, Holger , SCHNELLER, Arnold , GRANDE, Jürgen , SCHUTH, Silke , BÖHM, Gitte , BRAUNAGEL, Alfred
CPC分类号： A61K8/0241 , A61K8/73 , A61K2800/412 , A61K2800/654 , A61Q1/02 , A61Q19/00
摘要： The present invention relates to a topical preparation containing spherical microparticles as the essential component. Said microparticles consist entirely or partially of at least one water-insoluble linear polyglucan.
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7.发明公开
公开(公告)号：EP1124896A1
公开(公告)日：2001-08-22
申请号：EP99944385.6
申请日：1999-08-13
发明人： BENGS, Holger , GRANDE, Jürgen , SCHUTH, Silke , BÖHM, Gitte , SCHNELLER, Arnold , BRUNNER, Anette
CPC分类号： C08J3/14 , C08J2305/00 , C08L3/12 , C08L5/00 , Y10T428/2982 , C08L2666/02
摘要： The present invention relates to a method for preparing smooth-surface spherical microparticles which are completely or partially made of at least one water-insoluble linear polysaccharide. This method involves dissolving the at least one water-insoluble linear polysaccharide in a solvent or a mixture of solvents, introducing the solution into a precipitation agent or a mixture of precipitation agents, optionally cooling the mixture thus obtained, and separating the microparticles thus formed. The precipitation agent used consists of at least one water-soluble cellulose derivative. This invention also relates to microparticles obtained according to this method.
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