专利检索 ap:("Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER BBN)" OR "Universitat Autònoma De Barcelona" OR "Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER BBN)") AND inv:"VÁZQUEZ GÓMEZ, Esther" 第 1 页

1.

发明公开
INCLUSION BODIES, BACTERIAL CELLS AND COMPOSITIONS CONTAINING THEM AND USES THEREOF 审中-公开
标题翻译：包容性，细菌细胞和含有组合物及其

公开(公告)号：EP2377946A1

公开(公告)日：2011-10-19

申请号：EP09836114.0

申请日：2009-12-22

申请人： Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER BBN) , Universitat Autònoma De Barcelona , Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER BBN)

发明人： VECIANA MIRO, Jaume , RATERA BASTARDAS, Inmaculada , DÍEZ GIL, César , VILLAVERDE CORRALES, Antonio Pedro , VÁZQUEZ GÓMEZ, Esther , GARCÍA FRUITÓS, Elena

IPC分类号： C12P21/02 , C12N15/62 , C07K14/00

CPC分类号： C12P21/02 , A61K38/162 , C07K2319/60 , Y10T428/2982

摘要： The present invention refers to an isolated inclusion body comprising a polypeptide characterised in that the inclusion body is particulate in form. The present invention also refers to a bacterial cell comprising said inclusion body. The present invention additionally refers to a composition comprising said inclusion body and a eukaryotic cell. The present invention also refers to a composition comprising said inclusion body and an animal or plant tissue. The present invention also refers to the uses of said inclusion bodies as medicines and stimulators of cell proliferation and tissue regeneration.

摘要翻译： 本发明涉及分离的包涵体的包含多肽DASS包涵体在形式颗粒。因此，本发明涉及一种细菌细胞包含所述包涵体。另外，本发明是指包含所述包涵体和真核细胞的组合物。因此，本发明涉及包含所述包涵体和动物或植物组织的组合物。因此，本发明涉及到所述包涵体作为药物和细胞增殖和组织再生的刺激的用途。

2.

发明授权
METHODS AND REAGENTS FOR EFFICIENT AND TARGETED DELIVERY OF THERAPEUTIC MOLECULES TO CXCR4 CELLS 有权
标题翻译：有效和有针对性地将治疗性分子递送至CXCR4细胞的方法和试剂

公开(公告)号：EP2663336B1

公开(公告)日：2017-08-09

申请号：EP12704711.6

申请日：2012-01-13

申请人： Universitat Autònoma de Barcelona , Fundacio Institut de Recerca de l'Hospital de la Santa Creu i sant Pau , Centro de Investigación Biomédica en Red

发明人： VILLAVERDE CORRALES, Antonio , VÁZQUEZ GÓMEZ, Esther , CÉSPEDES NAVARRO, María Virtudes , CASANOVA RIGAT, Isolda , FERRER MIRALLES, Neus , MANGUES BAFALLUY, Ramon , UNZUETA ELORZA, Ugutz

IPC分类号： A61K47/50 , C07K14/435 , C12N15/62

CPC分类号： A61K38/10 , A61K47/62 , A61K47/66 , C07K7/08 , C07K14/00 , C07K14/43504 , C12N15/62

摘要： The invention relates to conjugates comprising a targeting moiety specific for the CXCR4 based on the polyphemusin-derived peptide and a therapeutic or imaging agent. The invention relates as well to the application of said conjugates for the therapy and diagnostics which require the specific targeting to CXCR4+ cells.

摘要翻译： 本发明涉及包含基于聚肌球蛋白衍生肽的CXCR4特异性靶向部分和治疗剂或成像剂的缀合物。本发明还涉及所述缀合物用于需要对CXCR4 +细胞进行特异性靶向的治疗和诊断的应用。