公开(公告)号：EP4382115A1

公开(公告)日：2024-06-12

申请号：EP22853439.2

申请日：2022-08-02

申请人： Chung Ang University Industry Academic Cooperation Foundation ,  HAPLNSCIENCE INC.

发明人： KIM, Dae Kyong ,  KIM, Yong Soon ,  BACK, Moon Jung ,  PYO, Jung Hoon ,  KIM, David ,  PIAO, Yong Wei ,  YEOM, Min A

IPC分类号： A61K38/16 ,  A61K45/06 ,  A61P43/00

CPC分类号： A61P43/00 ,  A61K38/16 ,  A61K45/06

摘要： Disclosed in the present disclosure are, a pharmaceutical composition for preventing or treating a fibrotic disease including a hyaluronan and proteoglycan link protein 1 (HAPLN1) or a gene encoding the same as an active ingredient, and a method for preventing or treating the fibrotic disease using the composition. According to the present disclosure, by preventing and inhibiting fibrosis of cells or tissues, the development or progression of various diseases caused by fibrosis may be fundamentally inhibited, thereby preventing or treating such diseases.

公开(公告)号：EP4458370A1

公开(公告)日：2024-11-06

申请号：EP22916815.8

申请日：2022-12-29

申请人： HAPLNSCIENCE INC.

发明人： KIM, Dae Kyong ,  KIM, Yong Soon ,  BACK, Moon Jung ,  CHAE, Dong Kyu ,  PYO, Jung Hoon ,  KIM, David

IPC分类号： A61K38/17 ,  A61P27/02 ,  A61P27/04

摘要： Disclosed are a pharmaceutical composition for prevention or treatment of dry eye disease, including hyaluronan and proteoglycan link protein 1 (HAPLN1) as an active ingredient, and a method for preventing or treating dry eye disease by using same. According to the present disclosure, dry eye disease may be effectively and stably prevented or treated, and side effects are reduced as compared to conventional products.