公开(公告)号：EP1576146A2

公开(公告)日：2005-09-21

申请号：EP03817177.3

申请日：2003-06-03

申请人： Curagen Corporation

发明人： ALSOBROOK, John P., II ,  ALVAREZ, Enrique ,  ANDERSON, David W. ,  BOLDOG, Ferenc L. ,  CASMAN, Stacie J. ,  CATTERTON, Elina ,  CHAPOVAL, Andrei ,  CRABTREE-BOKOR, Julie R. ,  EDINGER, Shlomit R. ,  ELLERMAN, Karen ,  ETTENBERG, Seth ,  GANGOLLI, Esha A. ,  GERLACH, Valerie L. ,  GORMAN, Linda ,  GUNTHER, Erik ,  GUO, Xiaojia ,  GUSEV, Vladimir Y. ,  HERRMANN, John L. ,  JI, Weizhen ,  KEKUDA, Ramesh ,  LI, Li ,  LIU, Xiaohong ,  MACDOUGALL, John R. ,  MACLACHLAN, Timothy ,  MALYANKAR, Uriel M. ,  MEZICK, Amanda J. ,  MILLET, Isabelle ,  MISHRA, Vishnu S. ,  PADIGARU, Muralidhara ,  PATTURAJAN, Meera ,  PENA, Carol E. A. ,  PEYMAN, John A. ,  RAHA, Debasish ,  RASTELLI, Luca ,  RIEGER, Daniel K. ,  ROTHENBERG, Mark E. ,  SCIORE, Paul ,  SHENOY, Suresh G. ,  SHIMKETS, Richard A. ,  SMITHSON, Glennda ,  SPYTEK, Kimberly A. ,  STONE, David J. ,  VERNET, Corine A.M. ,  VOSS, Edward Z. ,  ZHONG, Mei ,  ZHONG, Haihong

IPC分类号： C12N1/00

CPC分类号： C12N1/00

摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

摘要翻译： 本文公开了编码新多肽的核酸序列。 还公开了由这些核酸序列编码的多肽，以及免疫特异性结合多肽的抗体，以及对多肽具有特异性的新多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 还包括载体，宿主细胞，抗体和用于产生多肽和多核苷酸的重组方法，以及使用它们的方法。 本发明进一步公开了用于诊断，治疗和预防涉及任何一种这些新型人核酸和蛋白质的疾病的治疗，诊断和研究方法。