公开(公告)号：EP1101492A4

公开(公告)日：2002-09-25

申请号：EP99929875

申请日：1999-07-16

申请人： DAIICHI FINE CHEM CO LTD

发明人： IGETA KATSUHIRO ,  TOBETTO KENJI ,  SAIKI IKUO ,  ODAKE SHINJIRO ,  FUJISAWA TETSUNORI ,  MATSUO TETSU ,  OKU TOHRU

IPC分类号： A61K31/16 ,  A61K31/165 ,  A61K31/215 ,  A61K31/35 ,  A61K31/415 ,  A61K31/66 ,  A61K31/70 ,  A61P37/00

CPC分类号： A61K31/70 ,  A61K31/16 ,  A61K31/165 ,  A61K31/215 ,  A61K31/35 ,  A61K31/415 ,  A61K31/66

摘要： Drugs characterized by containing hydroxamic acid derivatives as the active ingredient which are efficacious in treating and/or preventing allergies, in particular, type I and/or type II allergies, etc. These drugs exert therapeutic and/or preventive effects on inflammation, rhinitis, conjunctivitis, bronchial asthma, atopic dermatitis (dermatitis, enteritis, etc.) and allergic digestive inflammation. Use of these drugs achieves the effects of: (A) inhibiting the proliferation of colonies of blood cells (lymphocytes, etc.) in an affected part; and/or (B) relieving inflammation caused by the migration, infiltration, accumulation, etc. of blood cells (lymphocytes, etc.) into an affected part; and/or (C) regulating the pathophysiological functions of cells such as blood cells (lymphocytes, etc.), Langerhans cells and dendritic cells; and/or (D) regulating the production of antibodies, in particular, IgE in the plasma, thus being useful in treating and/or preventing diseases or pathological conditions in the affected parts.