利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

10 条记录 (耗时 0.014 秒)

    Novel lactic acid derivatives and liquid crystal compositions containing the same
    2.
    发明公开
    Novel lactic acid derivatives and liquid crystal compositions containing the same 失效
    MilchsäurederivatundFlüssigkristallzusammensetzungmit diesem Derivat。

    公开(公告)号：EP0329153A2

    公开(公告)日：1989-08-23

    申请号：EP89102756.7

    申请日：1989-02-17

    申请人： DAINIPPON INK AND CHEMICALS, INC. ,  KAWAMURA INSTITUTE OF CHEMICAL RESEARCH

    发明人： Takehara, Sadao ,  Shoji, Tadao ,  Ogawa, Hiroshi ,  Fujisawa, Toru ,  Osawa, Masashi

    IPC分类号： C09K19/12 ,  C09K19/20 ,  C07C69/90 ,  C07C69/732

    CPC分类号： C09K19/126 ,  C09K19/2021

    摘要： compound represented by formula (I):
    wherein R 1 represents an alkyl group having from 1 to 18 carbon atoms; R 2 represents an alkyl group having from 2 to 16 carbon atoms; rings A, B, C, and D each represents a 1,4-phenylene group or a 1,4-phenylene group having one or two halogen atoms; Y represents a single bond,
    m and n each represents 0 or 1; p represents 0, 1, or 2; q represents 0 or an integer of from 1 to 6; and C * and C" each represents an asymmetric carbon atom in an (S)- or (R)-configuration, and a liquid crystal composition containing the compound of formula (I). The compound of formula (I) is a chiral liquid crystal compound exhibiting large spontaneous polarization, a long helical pitch, an SC * phase in a broad temperature range including room temperature, satisfactory orientation, and a high rate of response.

    摘要翻译： 由式（I）表示的化合物：其中R 1表示具有1至18个碳原子的烷基; R2表示具有2至16个碳原子的烷基; 环A，B，C和D各自表示具有一个或两个卤素原子的1,4-亚苯基或1,4-亚苯基; Y表示单键， - @ -O-或-O- m和n各自表示0或1; p表示0,1或2; q表示0或1至6的整数; 和C *和C **分别表示（S） - 或（R） - 构型中的不对称碳原子，和含有式（I）化合物的液晶组合物。 式（I）化合物是在包括室温，令人满意的取向和高反应率的宽温度范围内表现出大的自发极化，长螺距，SC *相的手性液晶化合物。

    Sulfated tocopheryl oligosaccharides and antiviral agents including the same as active ingredients
    3.
    发明公开
    Sulfated tocopheryl oligosaccharides and antiviral agents including the same as active ingredients 失效
    Sulfatierte Tocopherol-Oligosaccaride und antivirale Mittel，die diese als Wirkstoffe enthalten。

    公开(公告)号：EP0506048A1

    公开(公告)日：1992-09-30

    申请号：EP92105212.2

    申请日：1992-03-26

    申请人： DAINIPPON INK AND CHEMICALS, INC.

    发明人： Shoji, Tadao ,  Ikushima, Naoya ,  Katsuraya, Kaname ,  Takahashi, Nahoko ,  Kobayashi, Fusayo ,  Uryu, Toshiyuki ,  Yoshida, Takashi ,  Yamamoto, Naoki ,  Nakashima, Hideki

    IPC分类号： C07H17/065 ,  A61K31/70

    CPC分类号： C07H17/065 ,  A61K31/70

    摘要： The present invention relates to novel tocopheryl oligosaccharides, acylated tocopheryl oligosaccharides, sulfated tocopheryl oligosaccharides, and antiviral agents including the sulfated tocopheryl oligosaccharides as active ingredients. In the tocopheryl oligosaccharide, the hydrogen atom of the hydroxy group at the 1-position in the terminal sugar moiety of an oligosaccharide which consists of 3 ∼ 20 of identical or different repeating monosaccharide units selected from the group consisting of glucose, galactose, mannose, talose, idose, altrose, allose, glucose, xylose, arabinose, rhamnose, fucose, and fructose, which are glycoside-linked, is substituted by a tocopherol group. In the acylated tocopheryl oligosaccharides, each of any hydroxy group of the sugar moiety, other than the hydroxy group at the 1-position in the terminal sugar moiety of the oligosaccharide described above, is protected by an acyl group. The antiviral agents including the sulfated tocopheryl oligosaccharides or the biologically acceptable salt of the same as active ingredients have low toxicities and exhibit improved antiviral action, especially against the Human Immunodeficiency Virus.

    摘要翻译： 本发明涉及新的生育酚低聚糖，酰化生育酚低聚糖，硫酸生育酚寡糖，以及包含硫酸化生育酚寡糖作为活性成分的抗病毒剂。 在生育酚低聚糖中，寡糖的末端糖部分的1位的羟基的氢原子由3个相同或不同的重复单糖单元组成，选自葡萄糖，半乳糖，甘露糖， 与糖生成酚基取代的与糖苷连接的谷糖，偶氮，阿卓糖，阿洛糖，葡萄糖，木糖，阿拉伯糖，鼠李糖，岩藻糖和果糖。 在酰化的生育酚低聚糖中，除了上述寡糖的末端糖部分的1位以外的除了羟基以外的糖部分的任何羟基都被酰基保护。 包括硫酸生育酚寡糖或与生物活性成分相同的生物学上可接受的盐的抗病毒剂具有低毒性，并表现出改善的抗病毒作用，特别是针对人类免疫缺陷病毒。

    Sulfated oligoglycoside acylate and antiviral agent containing the same as active ingredient
    4.
    发明公开
    Sulfated oligoglycoside acylate and antiviral agent containing the same as active ingredient 失效
    Sulfatiertes Oligoglykosidacylat und dieses als Wirkstoff enthaltendes antivirales Mittel。

    公开(公告)号：EP0606882A1

    公开(公告)日：1994-07-20

    申请号：EP94100286.7

    申请日：1994-01-11

    申请人： DAINIPPON INK AND CHEMICALS, INC.

    发明人： Shoji, Tadao ,  Kasai, Akira ,  Misumi, Osamu ,  Ikushima, Naoya ,  Yamamoto, Naoki ,  Nakashima, Hideki ,  Inazawa, Kazuhiko ,  Takahashi, Nahoko

    IPC分类号： C07H17/065 ,  C07H15/203 ,  C07H15/04 ,  C08B37/00 ,  A61K31/70

    CPC分类号： C07H15/203 ,  C07H15/04 ,  C07H17/065

    摘要： A sulfated oligoglycoside acylate comprising monosaccharides of a single or two kinds as the constituents, wherein the hydrogen in the hydroxyl group at the 1-position of a reducing end sugar of the oligosaccharide formed via the glycoside bond of these monosaccharides has been substituted with an aglycon selected from a group consisting of alkyl groups, aromatic alkyl groups, aromatic alkoxy groups and tocopheryl groups ; from 12 to 80 % of the residual hydroxyl groups have been acylated with an acyl group selected from a group consisting of aliphatic acyl groups and aromatic acyl groups ; and 88 to 20 % thereof have been sulfated ; or a physiologically acceptable salt thereof provided that compounds wherein the aglycon is an alkyl group and the acyl group is an aliphatic acyl group are excluded is disclosed. Further, an antiviral agent, which exerts a long-lasting antiviral action particularly on HIV, containing said compound as an active ingredient is disclosed.

    摘要翻译： 一种包含单一或两种单糖作为组分的硫酸化低聚糖苷酰化物，其中通过这些单糖的糖苷键形成的寡糖在还原性末端糖的1位上的羟基中的氢被糖苷配基取代 选自烷基，芳族烷基，芳族烷氧基和生育酚基; 残余羟基的12至80％已经用选自脂族酰基和芳族酰基的酰基酰化; 88％〜20％已被硫酸化; 或其生理上可接受的盐，其中排除了其中糖苷配基是烷基和酰基是脂族酰基的化合物。 此外，公开了以含有所述化合物作为有效成分的抗HIV病毒作用，特别是HIV的长效抗病毒作用。