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公开(公告)号：EP3151889A4
公开(公告)日：2018-01-03
申请号：EP15806240
申请日：2015-06-08
申请人： DANCE BIOPHARM INC
发明人： STEDMAN BENJAMIN , FINK JIM , MOLLOY LISA
IPC分类号： A61M5/315
CPC分类号： A61M11/007 , A61M5/3145 , A61M15/0005 , A61M15/0085 , A61M15/0086 , A61M2016/0021 , A61M2016/0027 , A61M2205/053 , A61M2205/502 , A61M2205/52 , A61M2205/75 , A61M2205/8206 , A61M2209/10
摘要： Self-puncturing liquid drug cartridges and an associated inhaler are used to deliver one more separate doses of an aerosolized liquid drug. A cartridge includes a needle assembly coupled to a drug container. The needle assembly includes a hollow needle and is reconfigurable from a first configuration to a second configuration upon insertion of the cartridge into the inhaler. In the first configuration, the hollow needle does not extend into the container. In the second configuration, the hollow needle extends into the container. The inhaler includes an aerosol generator that includes a vibratable membrane that aerosolizes liquid drug ejected from the cartridge for inhalation by a patient.
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公开(公告)号：EP3164221A4
公开(公告)日：2018-07-18
申请号：EP15814884
申请日：2015-06-24
申请人： DANCE BIOPHARM INC
发明人： FINK JIM , MOLLOY LISA , MACLOUGHLIN RONAN , LILLIS CLAIR ELIZABETH , CASEY MICHAEL JOSEPH , MULLINS JOHN MATTHEW , HYLAND KIERAN JAMES , GREHAN JOSEPH MARTIN , SMITH NIALL SCOTT
IPC分类号： B05B1/08
CPC分类号： A61M15/0021 , A61M11/005 , A61M15/002 , A61M15/0085 , A61M2016/0021 , A61M2016/0027 , A61M2016/003 , A61M2205/3331 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/584 , A61M2205/6018 , A61M2205/6054 , A61M2205/6072 , A61M2205/8206 , A61M2206/11
摘要： Embodiments provide aerosolization device for providing aerosolized medicament to user. The aerosolization device includes conduit, aerosol generator, fluid receiving chamber, restrictor within the conduit, and indicator mechanism. Conduit has an inner wall and a mouthpiece end for causing an inspiratory flow. Aerosol generator includes a vibratable mesh laterally offset from the inner wall. Fluid receiving chamber receives liquid medicament. At least a portion of chamber is tapered such that liquid medicament is directed onto vibratable mesh for aerosolization. Restrictor defines a plurality of apertures that provide increases in pressure differential that vary with inspiratory flow rate within conduit and provide relatively laminar flow downstream of restrictor. Indicator mechanism indicates a state of flow parameters relative to a predefined range. Aerosol generator is configured to aerosolize at least a portion of liquid medicament only when flow parameters of the inspiratory flow are within range.
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公开(公告)号：EP3164222A4
公开(公告)日：2018-02-28
申请号：EP15816007
申请日：2015-06-24
申请人： DANCE BIOPHARM INC
发明人： FINK JIM , MOLLOY LISA , MACLOUGHLIN RONAN , LILLIS CLAIRE ELIZABETH , CASEY MICHAEL JOSEPH , MULLINS JOHN MATTHEW , HYLAND KIERAN JAMES , GREHAN JOSEPH MARTIN
CPC分类号： A61M15/002 , A61M11/005 , A61M15/0021 , A61M15/0085 , A61M2016/0021 , A61M2016/0027 , A61M2016/003 , A61M2205/3331 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/584 , A61M2205/6018 , A61M2205/6054 , A61M2205/6072 , A61M2205/8206 , A61M2206/11
摘要： In one aspect, embodiments of the present invention provide an aerosolization device for ensuring proper delivery of an aerosolized medication to a user's respiratory system. The aerosolization device may include a conduit, an aerosol generator, a restrictor disposed within the conduit, and an indicator mechanism. The conduit may include a mouthpiece end by which a user may cause inspiratory flow through the conduit. The aerosol generator may include a vibratable mesh. The restrictor may define a plurality of apertures disposed along an outer periphery of the restrictor configured to provide an increase in pressure differential that varies with an inspiratory flow rate within the conduit and to provide a relatively laminar flow downstream of the restrictor compared to upstream of the restrictor. The indicator mechanism may indicate to a user a state of a parameter of the inspiratory flow relative to a predefined desired range.
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公开(公告)号：EP3226938A4
公开(公告)日：2018-07-18
申请号：EP15864453
申请日：2015-12-04
申请人： DANCE BIOPHARM INC
发明人： FINK JIM , SHAWVER MICHAEL , MOLLOY LISA , STEDMAN BEN
CPC分类号： A61M15/0066 , A61K9/0078 , A61K38/28 , A61M11/005 , A61M15/0021 , A61M15/0085 , A61M15/0091 , A61M2016/0021 , A61M2016/0039 , A61M2202/00 , A61M2205/3569 , A61M2205/3584 , A61M2205/502 , A61M2205/505 , A61M2205/52 , A61M2230/005 , A61M2230/201 , A61M2230/40
摘要： An insulin dispenser receives blood glucose readings wirelessly from a blood glucose monitor, and calculates an insulin dose based on the historical response of the particular patient to prior insulin doses. The insulin dispenser preferably nebulizes an insulin-containing fluid for inhalation by the patient.
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公开(公告)号：EP3151891A4
公开(公告)日：2018-04-25
申请号：EP15806485
申请日：2015-06-08
申请人： DANCE BIOPHARM INC
发明人： STEDMAN BENJAMIN , FINK JIM , MOLLOY LISA , SANDER MATT
CPC分类号： A61M11/007 , A61M5/3145 , A61M15/0005 , A61M15/0085 , A61M15/0086 , A61M2016/0021 , A61M2016/0027 , A61M2205/053 , A61M2205/502 , A61M2205/52 , A61M2205/75 , A61M2205/8206 , A61M2209/10
摘要： Self-puncturing liquid drug cartridges and an associated inhaler are used to deliver one more separate doses of an aerosolized liquid drug. A cartridge includes a needle assembly coupled to a drug container. The needle assembly includes a hollow needle and is reconfigurable from a first configuration to a second configuration upon insertion of the cartridge into the inhaler. In the first configuration, the hollow needle does not extend into the container. In the second configuration, the hollow needle extends into the container. The inhaler includes an aerosol generator that includes a vibratable membrane that aerosolizes liquid drug ejected from the cartridge for inhalation by a patient.
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公开(公告)号：EP2986268A4
公开(公告)日：2016-11-23
申请号：EP14785659
申请日：2014-04-16
申请人： DANCE BIOPHARM INC
发明人： PATTON JOHN S , PATTON RYAN S , MOLLOY LISA , FINK JIM
CPC分类号： A61M15/0065 , A61M11/005 , A61M15/0085 , A61M2202/0468 , A61M2207/00 , A61M2209/045 , B05B11/00 , B05B11/30 , B65D83/42
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