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1.发明公开Process for preparation of (R)-1,2-propanediol by microbes 有权Verfahren zur Herstellung von（R）-1,2-丙二醇手套Mikroben
公开(公告)号：EP1219715A1
公开(公告)日：2002-07-03
申请号：EP01130920.0
申请日：2001-12-27
申请人： DAISO CO., LTD.
CPC分类号： C12R1/38 , C12P7/18 , C12P41/001
摘要： A process for preparation of (R)-1,2-propanediol which comprises cultivating a microorganism belonging to genus Pseudomonas or genus Alcaligenes which has ability to assimilate (S)-1,2-propanediol as a single carbon source, in a culture medium containing racemic 1,2-propanediol as a single carbon source and then isolating the remaining (R)-1,2-propanediol from the culture broth.
摘要翻译： 一种制备（R）-1,2-丙二醇的方法，其包括在培养基中培养属于具有同化（S）-1,2-丙二醇作为单一碳源的能力的假单胞菌属或产碱杆菌属的微生物 含有外消旋1,2-丙二醇作为单一碳源，然后从培养液中分离剩余的（R）-1,2-丙二醇。
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2.发明公开Process for the preparation of optically active 1,2-diols by cultivating microorganisms 审中-公开一种通过培养微生物制备光学活性的1,2-二醇的过程
公开(公告)号：EP1167534A3
公开(公告)日：2002-04-17
申请号：EP01115843.3
申请日：2001-06-28
申请人： DAISO CO., LTD.
CPC分类号： C12P7/42 , C12P7/18 , C12P41/001
摘要： A process for the preparation of an optically active 1,2-diol compound of the following formula: wherein R is an alkyl group, hydroxy substituted alkyl group, or alkenyl group, which comprises reacting a corresponding racemic 1,2-diol compound with a strain belonging to the genus Alcaligenes which is cultivated under aeration.
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3.发明公开Process for preparing optically active 4-halogeno-1, 3-butanediol and its derivatives by microorganism 有权一种用于通过微生物来生产光学活性的1,2,4-丁三醇和光学活性的3-羟基γ-丁内酯的过程
公开(公告)号：EP1096019A1
公开(公告)日：2001-05-02
申请号：EP00122385.8
申请日：2000-10-25
申请人： DAISO CO., LTD.
CPC分类号： C12P7/18 , C12P7/62 , C12P17/04 , C12P41/002
摘要： A process for preparing an optically active 4-halogeno-1,3-butanediol and (R)-1,2,4-butanetriol or (S)-3-hydroxy-γ-butyrolactone which comprises reacting a racemic 4-halogeno-1,3-butanediol with a specific microorganism belonging to the genus Pseudomonas.
摘要翻译： 一种制备光学活性4-卤代到1,3-丁二醇和（R）-1,2,4-丁三醇或（S）-3-羟基-γ-丁内酯该方法包括使外消旋4-卤代-1-过程 1,3-丁二醇与特定的微生物属于假单胞菌属。
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4.发明授权Method for producing optically active 3-chloro-2-methyl-1,2-propanediol taking advantage of microorganism 有权一种用于光学活性的3-氯-2-甲基-1,2-丙二醇的微生物制备方法
公开(公告)号：EP1550730B1
公开(公告)日：2007-08-29
申请号：EP05250004.8
申请日：2005-01-04
申请人： DAISO CO., LTD.
CPC分类号： C12P41/001 , C12P7/18
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公开(公告)号：EP1408107A3
公开(公告)日：2006-05-24
申请号：EP03022819.1
申请日：2003-10-07
申请人： DAISO CO., LTD.
发明人： Nakagawa, Atsushi , Suzuki, Toshio , Shinmyo, Atsuhiko, c/o Nara Institute of Science , Kato, Ko, c/o Nara Institute of Science , Idogaki, Hideaki
CPC分类号： C12P41/005 , C07K2319/02 , C12N9/18 , C12P7/42 , C12P7/62 , C12P17/04
摘要： The present invention is to provide a gene having asymmetric hydrolase activity which is useful for synthesis of an optically active carboxylic acid, its antipode ester, and lactone, and a hydroxycarboxylic ester asymmetric hydrolase enzyme (EnHCH) derived from Enterobacter sp . DS-S-75 strain (FERM BP-5494) which is bacteria belonging to the genus Enterobacter , a EnHCH gene shown by base sequence of SEQ.ID.NO: 1, a gene encoding a protein having an amino acid sequence of SEQ.ID.NO: 2, and E. coli DH5α (pKK-EnHCH) deposited to International Patent Organism Depositary, National Institute of Advanced Industrial Science and Technology as a deposition No. FERM BP-08466.
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6.发明公开Method for producing optically active 3-chloro-2-methyl-1,2-propanediol taking advantage of microorganism 有权Verfahren zur mikrobiologischen Herstellung von optisch aktiven 3-氯-2-甲基-1,2-丙二醇
公开(公告)号：EP1550730A1
公开(公告)日：2005-07-06
申请号：EP05250004.8
申请日：2005-01-04
申请人： DAISO CO., LTD.
IPC分类号： C12P41/00
CPC分类号： C12P41/001 , C12P7/18
摘要： The present invention provides a method for obtaining optically active 3-chloro-2-methyl-1,2-propanediol, the method comprising: a first step of letting at least one kind of microorganism or processed product thereof having an ability to leave untouched (R)-3-chloro-2-methyl-1,2-propanediol or (S)-3-chloro-2-methyl-1,2-propanediol in the presence of an enantiomeric 3-chloro-2-methyl-1,2-propanediol mixture act on an enantiomeric 3-chloro-2-methyl-1,2-propanediol mixture; and a second step of recovering the untouched optically active 3-chloro-2-methyl-1,2-propanediol.
摘要翻译： 本发明提供了一种获得光学活性3-氯-2-甲基-1,2-丙二醇的方法，该方法包括：使至少一种微生物或其加工产物具有保持不变的能力的第一步骤（ R）-3-氯-2-甲基-1,2-丙二醇或（S）-3-氯-2-甲基-1,2-丙二醇在对映异构体3-氯-2-甲基-1,2-丙二醇存在下， 2-丙二醇混合物作用于对映异构体3-氯-2-甲基-1,2-丙二醇混合物; 以及回收未接触的光学活性3-氯-2-甲基-1,2-丙二醇的第二步骤。
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7.发明授权Process for preparing an optically active 1,2,4-butanetriol and an optically active 3-hydroxy-gamma-butyrolactone by microorganism 有权一种用于通过微生物来生产光学活性的1,2,4-丁三醇和光学活性的3-羟基γ-丁内酯的过程
公开(公告)号：EP1096019B1
公开(公告)日：2004-04-21
申请号：EP00122385.8
申请日：2000-10-25
申请人： DAISO CO., LTD.
CPC分类号： C12P7/18 , C12P7/62 , C12P17/04 , C12P41/002
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8.发明公开Process for preparation of R-(-)-3-halogeno-1,2-propanediol by treatment with microorganism 失效（ - - ） - 3-卤代-1,2-丙二醇通过用微生物，一种制备的R处理。
公开(公告)号：EP0434393A2
公开(公告)日：1991-06-26
申请号：EP90313921.0
申请日：1990-12-19
申请人： Daiso Co., Ltd.
发明人： Kasai, Naoya , Suzuki, Toshio
CPC分类号： C12R1/38 , C12P7/18 , C12P41/001
摘要： A process for preparation of R-(-)-3-halogeno-1,2-propanediol which comprises cultivating in a medium containing racemate 3-halogeno-1,2-propanediol a bacterium, which, when cultivated in a medium containing racemate 3-halogeno-1,2-propanediol as a sole carbon source, can grow and proliferate, has an ability to assimilate S-(+)-3-halogeno-1,2-propanediol preferentially compared to R-(-)-3-halogeno-1,2-propanediol and belongs to the genus Pseudomonas , ot its culture cells; and recovering R-(-)-3-halogeno-1,2-propanediol from the resulting culture broth.
摘要翻译： （ - - ） - 一种用于制备的R处理3卤代-1,2-丙二醇，它包括在含有外消旋体3-卤代-1,2-丙二醇的细菌，其中的介质，当在含有外消旋体3的培养基中培养培养 （+） - - β-卤代-1,2-丙二醇作为唯一碳源时，可以生长和增殖，具有吸收的能力3-卤代-1,2-丙二醇优选相比于R - （ - ） - 3- 卤代-1,2-丙二醇和属于假单胞菌属，加时赛其培养细胞; 并回收的R - 从培养液中得到的3-卤代-1,2-丙二醇 - （ - ）。
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公开(公告)号：EP1408107B1
公开(公告)日：2010-03-24
申请号：EP03022819.1
申请日：2003-10-07
申请人： DAISO CO., LTD.
CPC分类号： C12P41/005 , C07K2319/02 , C12N9/18 , C12P7/42 , C12P7/62 , C12P17/04
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10.发明公开Process for the preparation of optically active 1,2-diols by cultivating microorganisms 审中-公开一种通过培养微生物制备光学活性的1,2-二醇的过程
公开(公告)号：EP1167534A2
公开(公告)日：2002-01-02
申请号：EP01115843.3
申请日：2001-06-28
申请人： DAISO CO., LTD.
CPC分类号： C12P7/42 , C12P7/18 , C12P41/001
摘要： A process for the preparation of an optically active 1,2-diol compound of the following formula:
wherein R is an alkyl group, hydroxy substituted alkyl group, or alkenyl group, which comprises reacting a corresponding racemic 1,2-diol compound with a strain belonging to the genus Alcaligenes which is cultivated under aeration.摘要翻译： 一种下式的光学活性的1,2-二醇化合物的制备方法：
worin R是烷基，羟基烷基substituiertem，或链烯基，该方法包括使相应的外消旋的1,2-二醇 化合物具有应变属于产碱杆菌属的所有其下通气培养。
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