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公开(公告)号：EP2059270B1
公开(公告)日：2013-06-12
申请号：EP07794211.8
申请日：2007-08-31
申请人： Doxa AB
CPC分类号： A61L31/088 , A61L27/306 , A61L33/027
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2.发明公开SIMPLIFIED CHEMICALLY BONDED CERAMIC BIOMATERIAL COMPRISING TWO BINDER SYSTEMS 审中-公开简化的化学结合陶瓷生物材料两个结合系统
公开(公告)号：EP2485776A1
公开(公告)日：2012-08-15
申请号：EP09740546.8
申请日：2009-10-09
申请人： Doxa AB
发明人： HERMANSSON, Leif , LÖÖF, Jesper , FARIS, Adam
CPC分类号： A61L27/446 , A61K6/0205 , A61K6/0835 , A61L24/0089 , A61L27/10 , C04B28/06 , C04B2111/00836 , C04B7/02 , C04B14/22 , C04B20/008 , C04B22/124 , C04B24/04 , C04B24/2641
摘要： The present invention generally relates to chemically bonded ceramic biomaterials, preferably a dental material or an implant material, comprising two binder systems. The main binder system forms a chemically bonded ceramic upon hydration thereof, and comprises powdered calcium aluminate and, optionally, minor amounts of calcium silicate. The second binder system is a cross-linking organic binder system which provides for initial crosslinking of the freshly mixed paste forming the biomaterial. The biomaterial also comprises inert filler particles. The inventive biomaterial is free from reactive glass and thus provides for a simplified two binder systems biomaterial with a reduced number of required reactive components The invention relates to a powdered composition for preparing the inventive chemically bonded ceramic biomaterial, and a paste from which the biomaterial is formed, as well as a kit comprising the powdered composition and hydration liquid, as well as methods and use of the biomaterial in dental and implant applications.
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公开(公告)号：EP1465580B1
公开(公告)日：2011-11-16
申请号：EP02793697.0
申请日：2002-12-19
申请人： Doxa AB
CPC分类号： A61L27/30 , A61L31/082 , C23C10/18 , C23C24/08
摘要： Surface coating method for deposition of a chemically bonded ceramic coating on a substrate, comprising the steps of preparing a curable coating slurry, depositing a coating of the slurry on at least a section of the substrate surface, and hardening the slurry. According to the invention the step of preparing a curable coating slurry comprises mixing calcium aluminate powder with water and at least one water-reducing-agent, such that a water-to-cement ratio in the range of 0.1 to 0.9 is achieved. The invention further relates to a biocompatible surface coating with a binder phase of calcium aluminate hydrate and a device coated with such a biocompatible surface coating.
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公开(公告)号：EP2182912A1
公开(公告)日：2010-05-12
申请号：EP07794184.7
申请日：2007-08-23
申请人： Doxa AB
发明人： HERMANSSON, Leif , LÖÖF, Jesper , ENGQVIST, Håkan
IPC分类号： A61K6/06
CPC分类号： A61K6/0008 , A61K6/0023 , A61K6/0631 , A61K6/0675 , C08L33/08 , A61K6/0835
摘要： A dental cement system, comprising an aqueous hydration liquid and a powdered material that essentially consists of an inorganic cement system, which powdered material has the capacity to form a complex, chemically bonded material with inorganic as well as organic phases with properties suitable for cementation of implant to another implant and/or to tooth or bone tissue. The invention relates to the powdered material and the hydration liquid, respectively, as well as the formed ceramic material and a kit comprising the system.
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公开(公告)号：EP2131878A1
公开(公告)日：2009-12-16
申请号：EP08712858.3
申请日：2008-02-29
申请人： Doxa AB
发明人： HERMANSSON, Leif , ENGQVIST, Håkan
CPC分类号： A61L24/02 , A61K6/0008 , A61K6/0088 , A61K6/024 , A61K6/0612 , A61K6/0631 , A61L24/0068 , A61L24/0089 , A61L27/10 , A61L27/105 , A61L27/427 , A61L27/446 , A61L2400/06 , A61K6/087 , C08L69/00 , A61K6/097 , C08L1/28
摘要： The present invention relates to ceramic precursor powder compositions and chemically bonded ceramic (CBC) materials, Ca-aluminate and/ or calcium silicate, and a composite biomaterial with prolonged shelf time of the precursor, suitable for orthopaedic applications with improved injectability. The present invention also relates to a method of manufacturing said cured material, bioelements, implants, or drug delivery carrier materials made by said cured material, a kit comprising the ceramic precursor powder and hydration liquid, as well as the use of said ceramic precursor powder and hydration liquid, or said cured material, for orthopaedic and dental applications,
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公开(公告)号：EP2059270A2
公开(公告)日：2009-05-20
申请号：EP07794211.8
申请日：2007-08-31
申请人： Doxa AB
CPC分类号： A61L31/088 , A61L27/306 , A61L33/027
摘要： The present invention deals with the use of alkaline chemically bonded ceramic systems based on Ca-aluminate as a thrombogenecity reducing coating material. The invention is especially intended for coating of devices used in the human or animal blood system.
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公开(公告)号：EP1551468B1
公开(公告)日：2008-12-31
申请号：EP03798636.1
申请日：2003-09-25
申请人： Doxa AB
IPC分类号： A61L27/10
CPC分类号： A61L27/10
摘要： The present invention pertains to injectable heat generating biocompatible ceramic compositions based on hydraulic calcium aluminate, which can be used for therapeutic treatment in vivo, such as tumour treatment, pain control, vascular treatment, drug activation etc, when curing in situ, and which form a biocompatible solid material that can be left in the body for prolonged periods of time without causing negative health effects. The present invention can also be used to restore the mechanical properties of the skeleton after cancerous diseases.
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公开(公告)号：EP1726319A1
公开(公告)日：2006-11-29
申请号：EP05104516.9
申请日：2005-05-26
申请人： Doxa AB
发明人： HERMANSSON, Leif
CPC分类号： A61F2/30767 , A61F2002/30064 , A61F2002/30808 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00131 , A61F2310/00592 , A61L27/30 , A61L27/32 , A61L27/50
摘要： Implant device having a coating of a chemically bonded ceramic material exhibiting improved adhesion of the coating to the surface, wherein the surface of the implant underlying the coating exhibits a surface structure containing cavities having a width "a", a depth "c", and a distance between neighbouring cavities "b", wherein 80
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9.发明公开
公开(公告)号：EP1689459A1
公开(公告)日：2006-08-16
申请号：EP04819997.0
申请日：2004-11-25
申请人： Doxa AB
发明人： HERMANSSON, Leif , ENGQVIST, Hakan , LÖÖF, Jesper
CPC分类号： A61L27/306 , A61K6/0631 , B82Y30/00 , C04B35/22 , C04B35/44 , C04B41/009 , C04B41/5024 , C04B41/5032 , C04B41/85 , C04B2111/00836 , C04B2235/3205 , C04B2235/781 , C04B35/10 , C04B35/48
摘要： The present invention relates to a coated implant for in vivo-anchoring of implants to a biological tissue or another implant, which coated implant comprises an implant having a pre-treated surface and on said pre-treated surface one or more layers of ceramic material chemically and/or mechanically bound to said pre-treated surface. Said one or more layers comprises mainly non-hydrated chemically bonded ceramic material, and each layer independently comprises a first binder phase selected from the group consisting of aluminates, silicates, phosphates, sulphates and combinations thereof. The invention further relates to method of manufacturing said coated implant, a ceramic paste and to a kit comprising said coated implant and ceramic paste. The invention is particularly suitable for dental and orthopaedic implants.
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公开(公告)号：EP1778163B1
公开(公告)日：2014-11-12
申请号：EP05774832.9
申请日：2005-08-17
申请人： Doxa AB
CPC分类号： A61L27/42 , A61K6/0008 , A61K6/0085 , A61K6/0091 , A61K6/0612 , A61K6/0643 , A61K6/0668 , A61K6/0675 , A61L27/105 , C04B28/02 , C04B28/06 , C04B28/34 , C04B2111/00836 , C04B20/0048 , C04B24/2641 , C04B14/42 , A61K6/083 , C08L33/08
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