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公开(公告)号：EP1687289A1
公开(公告)日：2006-08-09
申请号：EP04800486.5
申请日：2004-11-16
发明人： LU, Jianliang , MA, Tianwei , NAGPAL, Sunil , SHEN, Quanrong , WARSHAWSKY, Alan, M. , OCHOADA, Jason, Matthew , YEE, Ying, Kwong
IPC分类号： C07D307/77 , C07D405/12 , C07D407/10 , C07D407/12 , A61K31/12
CPC分类号： C07D405/12 , C07D307/80 , C07D407/12
摘要： The present invention relates to novel, non-secosteroidal, phenyl-benzofuran compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1α,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.
摘要翻译： 本发明涉及具有维生素D受体（VDR）调节活性的新型非 - 类固醇，苯基 - 苯并呋喃化合物，其比1α，25二羟基维生素D 3更低的高钙血症。 这些化合物可用于治疗骨疾病和牛皮癣。
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公开(公告)号：EP2029558B1
公开(公告)日：2010-03-10
申请号：EP07811915.3
申请日：2007-05-22
发明人： BELL, Michael, Gregory , DOTI, Robert, Anthony , DOWLING, Matthew, Scott , GENIN, Michael, James , LANDER, Peter, Ambrose , MA, Tianwei , MANTLO, Nathan, Bryan , OCHOADA, Jason, Matthew , STELZER, Lindsay, Scott , STITES, Ryan, Edward , WARSHAWSKY, Alan, M
IPC分类号： C07D249/12 , C07D401/12 , C07D403/12 , C07D409/12 , A61K31/4192 , A61P3/06
CPC分类号： C07D249/06 , C07D401/12 , C07D403/12 , C07D409/12 , C07D417/12
摘要： Compounds of formula (I) wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.
摘要翻译： 其中变量如本文所定义的式（I）化合物及其药物组合物和使用方法公开可用于治疗血脂异常和相关疾病。
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公开(公告)号：EP2029558A2
公开(公告)日：2009-03-04
申请号：EP07811915.3
申请日：2007-05-22
发明人： BELL, Michael, Gregory , DOTI, Robert, Anthony , DOWLING, Matthew, Scott , GENIN, Michael, James , LANDER, Peter, Ambrose , MA, Tianwei , MANTLO, Nathan, Bryan , OCHOADA, Jason, Matthew , STELZER, Lindsay, Scott , STITES, Ryan, Edward , WARSHAWSKY, Alan, M
IPC分类号： C07D249/12 , C07D401/12 , C07D403/12 , C07D409/12 , A61K31/4192 , A61P3/06
CPC分类号： C07D249/06 , C07D401/12 , C07D403/12 , C07D409/12 , C07D417/12
摘要： Compounds of formula (I) wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.
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公开(公告)号：EP2029547B1
公开(公告)日：2010-04-28
申请号：EP07797648.8
申请日：2007-05-22
发明人： BELL, Michael, Gregory , DOTI, Robert, Anthony , GENIN, Michael, James , LANDER, Peter, Ambrose , MA, Tianwei , MANNINEN, Peter, Rudolph , OCHOADA, Jason, Matthew , QU, Fucheng , STELZER, Lindsay, Scott , STITES, Ryan, Edward , WARSHAWSKY, Alan, M.
IPC分类号： C07D231/12 , C07D401/12 , C07D403/12 , C07D417/12 , A61P3/06
CPC分类号： C07D231/12 , C07D231/56 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12
摘要： Compounds of formula wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.
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公开(公告)号：EP2029547A1
公开(公告)日：2009-03-04
申请号：EP07797648.8
申请日：2007-05-22
发明人： BELL, Michael, Gregory , DOTI, Robert, Anthony , GENIN, Michael, James , LANDER, Peter, Ambrose , MA, Tianwei , MANNINEN, Peter, Rudolph , OCHOADA, Jason, Matthew , QU, Fucheng , STELZER, Lindsay, Scott , STITES, Ryan, Edward , WARSHAWSKY, Alan, M.
IPC分类号： C07D231/12 , C07D401/12 , C07D403/12 , C07D417/12 , A61P3/06
CPC分类号： C07D231/12 , C07D231/56 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12
摘要： Compounds of formula wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.
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