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1.发明授权
公开(公告)号：EP0059258B1
公开(公告)日：1984-05-30
申请号：EP81109393.9
申请日：1981-10-30
申请人： Eisai Co., Ltd.
发明人： Yamatsu, Isao , Inai, Yuichi , Abe, Shinya , Suzuki, Takeshi , Suzuki, Yoshikazu , Tagaya, Osamu , Suzuki, Kouichi , Abe, Kouichi , Yamada, Kouji
IPC分类号： C07C57/03 , C07C69/533 , C07C69/587 , C07C103/133 , C07C49/203 , A61K31/12 , A61K31/23 , A61K31/16
CPC分类号： A61K31/23 , A61K31/12 , A61K31/16 , C07C49/203 , C07C57/03
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2.发明授权
公开(公告)号：EP0054732B1
公开(公告)日：1984-06-20
申请号：EP81109391.3
申请日：1981-10-30
申请人： Eisai Co., Ltd.
发明人： Yamatsu, Isao , Inai, Yuichi , Abe, Shinya , Suzuki, Takeshi , Suzuki, Yoshikazu , Tagaya, Osamu , Suzuki, Kouichi , Abe, Kouichi , Yamada, Kouji
IPC分类号： C07C57/03 , C07C69/587 , C07C103/133 , A61K31/19 , A61K31/23 , A61K31/16
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3.发明公开Pharmaceutical preparations comprising polyprenyl compounds, especially as anti-cancer agents, and pharmaceutical compositions for the prevention and treatment of cancer and skin diseases 失效含有特别是医疗制剂Polyprenylderivate具有抗癌活性，癌症和皮肤病的预防和治疗的治疗组合物。
公开(公告)号：EP0059258A1
公开(公告)日：1982-09-08
申请号：EP81109393.9
申请日：1981-10-30
申请人： Eisai Co., Ltd.
发明人： Yamatsu, Isao , Inai, Yuichi , Abe, Shinya , Suzuki, Takeshi , Suzuki, Yoshikazu , Tagaya, Osamu , Suzuki, Kouichi , Abe, Kouichi , Yamada, Kouji
IPC分类号： C07C57/03 , C07C69/533 , C07C69/587 , C07C103/133 , C07C49/203 , A61K31/12 , A61K31/23 , A61K31/16
CPC分类号： A61K31/23 , A61K31/12 , A61K31/16 , C07C49/203 , C07C57/03
摘要： group, or
in which each of n and m is 0, 1 or 2, n + m is 0, 1 or 2,
and B is
or
[in which R represents a hydroxyl group, a lower alkoxy (wherein each of R, and R 2 is a hydrogen atom, a lower alkyl group or an aryl group)]; provided that R is a lower alkoxy or
especially as anti-cancer agent.摘要翻译： 药物组合物，其包含具有下式的聚异戊二烯类化合物：
Ñ -
4.发明公开Conjugated polyprenylcarboxylic acids and their derivatives as well as pharmaceutical preparations containing these compounds 失效共轭Polyprenylcarbonsäuren和它们的衍生物和含有它们的药物组合物。
公开(公告)号：EP0054732A1
公开(公告)日：1982-06-30
申请号：EP81109391.3
申请日：1981-10-30
申请人： Eisai Co., Ltd.
发明人： Yamatsu, Isao , Inai, Yuichi , Abe, Shinya , Suzuki, Takeshi , Suzuki, Yoshikazu , Tagaya, Osamu , Suzuki, Kouichi , Abe, Kouichi , Yamada, Kouji
IPC分类号： C07C57/03 , C07C69/587 , C07C103/133 , A61K31/19 , A61K31/23 , A61K31/16
摘要： A conjugated polyprenylcarboxylic acid and its derivative having the formula:
in which each of n and m is 0, 1 or 2, n+m is 1 or 2, A is
and R is a hydroxyl group, a lower alkoxy group or
wherein each of R, and R 2 represents a hydrogen atom, a lower alkyl group, or an aryl group; provided that R is
n is 1 and m is 0.
There are also descrived pharmaceutical preparations containing above compounds.
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