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公开(公告)号：EP2600902A1
公开(公告)日：2013-06-12
申请号：EP11815394.9
申请日：2011-08-05
申请人： Endoshape, Inc.
IPC分类号： A61K49/04
CPC分类号： C08F222/20 , A61K49/0442 , C08F214/16 , C08F222/1006 , C08F222/12 , C08F263/02 , C08F2218/20 , C08G2280/00 , C08L2201/12
摘要： Radiopaque polymer compositions and methods for making the compositions are provided. These radiopaque polymer compositions include shape memory polymer compositions comprising a crosslinked polymer network, the network comprising a first repeating unit derived from a monofunctional iodinated monomer and a second repeating unit derived from a multifunctional non-iodinated monomer wherein neither of the two monomers is fluorinated. Devices formed from radiopaque polymer compositions are also provided.
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公开(公告)号：EP2408409B1
公开(公告)日：2015-11-25
申请号：EP10753999.1
申请日：2010-03-16
申请人： Endoshape, Inc. , The Regents Of The University Of Colorado, A Body Corporate, A Colorado Non-Profit
发明人： LYONS, Michael, B. , TROMMETER, Julie, Marie , MANDAVA, Naresh , KAHOOK, Malik , SHANDAS, Robin , FOGELBERG, James , CASTLEBERRY, Jeffrey, Paul
CPC分类号： A61F9/00772 , A61F9/0017 , A61F2210/0014 , A61L27/04 , A61L27/14 , A61L27/50 , A61L2400/16 , A61L2430/16 , A61M25/00 , A61M25/01 , A61M25/04 , A61M31/002
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公开(公告)号：EP2413840A2
公开(公告)日：2012-02-08
申请号：EP10759456.6
申请日：2010-04-02
发明人： TROMMETER, Julie, Marie , LYONS, Michael, B. , CASTLEBERRY, Jeffrey, Paul , SHANDAS, Robin , FOGELBERG, James , JOHNSON, Stephen
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B2017/00477 , A61B2017/00778 , A61B2017/00871 , A61B2017/00898 , A61B2017/12054 , A61L31/04 , A61L31/14 , A61L2400/16 , A61L2430/36
摘要： Shape memory materials (SMM) are formed as coil-shaped vascular occlusion devices upon deployment. Shape memory polymer (SMP) materials are tailored through formulation for specific mechanical behavior of the coils. Concurrent coil diameter changes enhance the relative change in stiffness along the length of the coil. Interconnecting structures (104a/b) are formed on ends of elongated members (102a) in the pre-deployment shape for multiple coil insertion capability within an introducer. Channels (206) are formed in pre-deployment shape, elongate members (202) that allow access for injection of imaging contrast agent or concurrent placement of instruments. A single SMM occlusive device (300) transforms into multiple, smaller diameter coils (302b) in the deployed state to generate a complex occlusive structure. A SMM occlusive device (400) has a collapsed fabric (404) component attached to and extending along a sidewall during storage and insertion, and then deploys as a coil (402b) to form a single- or multiple-layer occlusive fabric surface within a center of the coil (402b).
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公开(公告)号：EP2413840B1
公开(公告)日：2016-08-17
申请号：EP10759456.6
申请日：2010-04-02
发明人： TROMMETER, Julie, Marie , LYONS, Michael, B. , CASTLEBERRY, Jeffrey, Paul , SHANDAS, Robin , FOGELBERG, James , JOHNSON, Stephen
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B2017/00477 , A61B2017/00778 , A61B2017/00871 , A61B2017/00898 , A61B2017/12054 , A61L31/04 , A61L31/14 , A61L2400/16 , A61L2430/36
摘要： Shape memory materials (SMM) are formed as coil-shaped vascular occlusion devices upon deployment. Shape memory polymer (SMP) materials are tailored through formulation for specific mechanical behavior of the coils. Concurrent coil diameter changes enhance the relative change in stiffness along the length of the coil. Interconnecting structures (104a/b) are formed on ends of elongated members (102a) in the pre-deployment shape for multiple coil insertion capability within an introducer. Channels (206) are formed in pre-deployment shape, elongate members (202) that allow access for injection of imaging contrast agent or concurrent placement of instruments. A single SMM occlusive device (300) transforms into multiple, smaller diameter coils (302b) in the deployed state to generate a complex occlusive structure. A SMM occlusive device (400) has a collapsed fabric (404) component attached to and extending along a sidewall during storage and insertion, and then deploys as a coil (402b) to form a single- or multiple-layer occlusive fabric surface within a center of the coil (402b).
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公开(公告)号：EP2408409B8
公开(公告)日：2016-06-08
申请号：EP10753999.1
申请日：2010-03-16
申请人： Endoshape, Inc. , The Regents Of The University Of Colorado, A Body Corporate, A Colorado Non-Profit
发明人： LYONS, Michael, B. , TROMMETER, Julie, Marie , MANDAVA, Naresh , KAHOOK, Malik , SHANDAS, Robin , FOGELBERG, James , CASTLEBERRY, Jeffrey, Paul
CPC分类号： A61F9/00772 , A61F9/0017 , A61F2210/0014 , A61L27/04 , A61L27/14 , A61L27/50 , A61L2400/16 , A61L2430/16 , A61M25/00 , A61M25/01 , A61M25/04 , A61M31/002
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公开(公告)号：EP2408409A2
公开(公告)日：2012-01-25
申请号：EP10753999.1
申请日：2010-03-16
申请人： Endoshape, Inc. , The Regents Of The University Of Colorado, A Body Corporate, A Colorado Non-Profit
发明人： LYONS, Michael, B. , TROMMETER, Julie, Marie , MANDAVA, Naresh , KAHOOK, Malik , SHANDAS, Robin , FOGELBERG, James , CASTLEBERRY, Jeffrey, Paul
CPC分类号： A61F9/00772 , A61F9/0017 , A61F2210/0014 , A61L27/04 , A61L27/14 , A61L27/50 , A61L2400/16 , A61L2430/16 , A61M25/00 , A61M25/01 , A61M25/04 , A61M31/002
摘要： An implantable ophthalmological device (10) in the form of a punctal plug or canalicular implant is configured for use at or near the nasolacrimal drainage system. In a deployed state, the device (10) may include an elongated body (25), an anchor (15) operably connected to the elongated body (25), a radially expanding occlusive feature disposed on an outer circumference of the elongated body (32), and a flange (30). The elongated body (25) may define a lumen (35) configured to receive a pharmacological treatment (55). The device (10) is made of a shape memory material such as a shape memory polymer.
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