公开(公告)号：EP0749321B1

公开(公告)日：2007-01-24

申请号：EP95911683.1

申请日：1995-02-09

申请人： Epitopix LLC

发明人： EMERY, Daryll A. ,  STRAUB, Darren E.

IPC分类号： A61K39/00 ,  A61K39/38 ,  A61K39/40 ,  A61K39/102 ,  A61K39/108 ,  A61K39/395 ,  A61K39/112 ,  A61K39/104 ,  C07K16/12

CPC分类号： C07K14/245 ,  A61K39/0258 ,  A61K39/0275 ,  A61K39/102 ,  G01N33/56911 ,  G01N33/56916 ,  Y02A50/474 ,  Y02A50/482 ,  Y10S424/823 ,  Y10S424/824 ,  Y10S424/825 ,  Y10S424/826 ,  Y10S530/825

摘要： The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a single strain or species of gram-negative bacteria or other organism, which are cross-reactive with siderophores produced by two or more strains, species or genera of gram-negative bacteria. The invention further provides a process for isolating and purifying the siderophore receptor proteins, and for preparing a vaccine containing the proteins. Also provided is a method for diagnosing gram-negative sepsis.

公开(公告)号：EP1848732B1

公开(公告)日：2016-07-27

申请号：EP06719369.8

申请日：2006-01-20

申请人： Epitopix, LLC

发明人： EMERY, Daryll A. ,  STRAUB, Darren E. ,  WONDERLING, Laura

IPC分类号： C07K14/24

CPC分类号： A61K39/0291 ,  A61K39/00 ,  A61K39/025 ,  A61K2039/54 ,  A61K2039/55 ,  A61K2039/552 ,  A61K2039/55505 ,  A61K2039/55566 ,  A61K2039/575 ,  C07K14/24 ,  C07K16/1228 ,  A61K2300/00