-
公开(公告)号：EP3659606A1
公开(公告)日：2020-06-03
申请号：EP19199387.2
申请日：2013-10-15
申请人： Epizyme, Inc.
IPC分类号： A61K31/5377 , C12Q1/68 , A61P35/00 , C12Q1/6886 , A61K31/4412 , A61K31/4545 , A61P1/18 , A61P11/00 , A61P13/08 , A61P13/12 , A61P15/00 , A61P25/00 , C07D211/86 , C07D405/12 , C07D405/14
摘要： The present invention relates to methods of treating cancer by administering the EZH2 inhibitor compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
-
公开(公告)号：EP3943485A1
公开(公告)日：2022-01-26
申请号：EP21175920.4
申请日：2012-04-13
申请人： Epizyme, Inc.
发明人： CHESWORTH, Richard , DUNCAN, Kenneth William , KEILHACK, Heike , WARHOLIC, Natalie , KLAUS, Christine , SEKI, Masashi , SHIROTORI, Syuji , KAWANO, Satoshi , WIGLE, Timothy James Nelson , KNUTSON, Sarah Kathleen , KUNTZ, Kevin Wayne
IPC分类号： C07D213/64 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D491/08 , C07D491/107 , A61K31/4412 , A61K31/444 , A61P35/00
摘要： The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
-
公开(公告)号：EP2908823A2
公开(公告)日：2015-08-26
申请号：EP13786351.0
申请日：2013-10-15
申请人： Epizyme, Inc.
IPC分类号： A61K31/5377 , C12Q1/68 , A61P35/00
CPC分类号： C07D405/14 , A61K31/4412 , A61K31/4545 , A61K31/5377 , C07D211/86 , C07D405/12 , C12Q1/6886
摘要： The present invention relates to methods of treating cancer by administering the EZH2 inhibitor compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
摘要翻译： 本发明涉及通过给有此需要的受试者施用EZH2抑制剂化合物和药物组合物来治疗癌症的方法。 本发明还涉及这些化合物用于研究或其他非治疗目的的用途。
-
公开(公告)号：EP3165520A1
公开(公告)日：2017-05-10
申请号：EP16173275.5
申请日：2012-04-13
申请人： Epizyme Inc
发明人： KUNTZ, Kevin Wayne , CHESWORTH, Richard , DUNCAN, Kenneth William , KEILHACK, Heike , WARHOLIC, Natalie , KLAUS, Christine , SEKI, Masashi , KNUTSON, Sarah , WIGLE, Timothy James Nelson
IPC分类号： C07D213/64 , C07D401/12 , C07D401/14 , C07D407/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D491/10 , C07D491/113 , A61K31/4427 , A61P35/00
CPC分类号： C07D213/64 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D491/048 , C07D491/08 , C07D491/10 , C07D491/113
摘要： The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and such compounds for use in treating cancer. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
摘要翻译： 本发明涉及取代的苯化合物。 本发明还涉及含有这些化合物和用于治疗癌症的这类化合物的药物组合物。 本发明还涉及这些化合物用于研究或其他非治疗目的的用途。
-
公开(公告)号：EP2697198B1
公开(公告)日：2016-06-08
申请号：EP12716968.8
申请日：2012-04-13
申请人： Epizyme, Inc.
发明人： KUNTZ, Kevin, Wayne , CHESWORTH, Richard , DUNCAN, Kenneth, William , KEILHACK, Heike , WARHOLIC, Natalie , KLAUS, Christine , SEKI, Masashi , KNUTSON, Sarah, K. , WIGLE, Timothy, James, Nelson
IPC分类号： C07D213/64 , C07D401/12 , C07D401/14 , C07D407/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D491/10 , C07D491/113 , A61K31/4427 , A61P35/00
CPC分类号： C07D213/64 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D491/048 , C07D491/08 , C07D491/10 , C07D491/113
-
公开(公告)号：EP2697198A1
公开(公告)日：2014-02-19
申请号：EP12716968.8
申请日：2012-04-13
申请人： Epizyme, Inc.
发明人： KUNTZ, Kevin, Wayne , CHESWORTH, Richard , DUNCAN, Kenneth, William , KEILHACK, Heike , WARHOLIC, Natalie , KLAUS, Christine , SEKI, Masashi , KNUTSON, Sarah, K. , WIGLE, Timothy, James, Nelson
IPC分类号： C07D213/64 , C07D401/12 , C07D401/14 , C07D407/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D491/10 , C07D491/113 , A61K31/4427 , A61P35/00
CPC分类号： C07D213/64 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D491/048 , C07D491/08 , C07D491/10 , C07D491/113
摘要： The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
-
公开(公告)号：EP4360712A2
公开(公告)日：2024-05-01
申请号：EP23217912.7
申请日：2012-04-13
申请人： Epizyme, Inc.
发明人： CHESWORTH, Richard , DUNCAN, Kenneth William , KEILHACK, Heike , WARHOLIC, Natalie , KLAUS, Christine , SEKI, Masashi , SHIROTORI, Syuji , KAWANO, Satoshi , WIGLE, Timothy James Nelson , KNUTSON, Sarah Kathleen , KUNTZ, Kevin Wayne
IPC分类号： A61P35/00
CPC分类号： C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D491/08 , C07D491/107 , C07D498/08 , A61K31/4412 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/551 , A61K31/553 , C07D213/64 , C07D405/14 , A61K31/5377 , A61P25/00 , A61P35/00 , A61P35/02 , A61P43/00
摘要： The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
-
公开(公告)号：EP3486234A1
公开(公告)日：2019-05-22
申请号：EP18200713.8
申请日：2012-04-13
申请人： Epizyme Inc
发明人： CHESWORTH, Richard , DUNCAN, Kenneth William , KEILHACK, Heike , WARHOLIC, Natalie , KLAUS, Christine , SEKI, Masashi , SHIROTORI, Syuji , KAWANO, Satoshi , WIGLE, Timothy James Nelson , KNUTSON, Sarah Kathleen , KUNTZ, Kevin Wayne
IPC分类号： C07D213/64 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D491/08 , C07D491/107 , A61K31/4412 , A61K31/444 , A61P35/00
摘要： The present invention relates to aryl- or heteroaryl-substituted benzene compounds (I) for use in treating a cell proliferative disorder.
-
公开(公告)号：EP3470396A1
公开(公告)日：2019-04-17
申请号：EP18189032.8
申请日：2012-04-13
申请人： Epizyme, Inc.
发明人： KUNTZ, Kevin Wayne , CHESWORTH, Richard , DUNCAN, Kenneth William , KEILHACK, Heike , WARHOLIC, Natalie , KLAUS, Christine , SEKI, Masashi , KNUTSON, Sarah , WIGLE, Timothy James Nelson
IPC分类号： C07D213/64 , C07D401/12 , C07D401/14 , C07D407/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D491/10 , C07D491/113 , A61K31/4427 , A61P35/00
摘要： The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and such compounds for use in treating cancer. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
-
公开(公告)号：EP3165520B1
公开(公告)日：2018-08-15
申请号：EP16173275.5
申请日：2012-04-13
申请人： Epizyme Inc
发明人： KUNTZ, Kevin Wayne , CHESWORTH, Richard , DUNCAN, Kenneth William , KEILHACK, Heike , WARHOLIC, Natalie , KLAUS, Christine , SEKI, Masashi , KNUTSON, Sarah , WIGLE, Timothy James Nelson
IPC分类号： C07D213/64 , C07D401/12 , C07D401/14 , C07D407/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D491/10 , C07D491/113 , A61K31/4427 , A61P35/00
CPC分类号： C07D213/64 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D491/048 , C07D491/08 , C07D491/10 , C07D491/113
摘要： The present invention relates to substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and such compounds for use in treating cancer. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.
-
-
-
-
-
-
-
-
-
搜索结果
15 条记录 (耗时 0.06 秒)
