HYDROLYSIS OF ACYLAMINO ACIDS
    9.
    发明授权
    HYDROLYSIS OF ACYLAMINO ACIDS 有权
    的酰基氨基酸水解

    公开(公告)号:EP1309541B1

    公开(公告)日:2010-05-26

    申请号:EP01956541.5

    申请日:2001-07-18

    IPC分类号: C07C227/20

    摘要: The invention provides a process for the preparation of racemic amino acids, characterized in that an acylamino acid of the general formula R1-CH(NH-CO-R2)COOH wherein R1 is hydrogen, a linear, branched or cyclic alkyl radical that has from 1 to 7 carbon atoms and that may contain substituents such as a hydroxyl, alkyloxy or alkylthio group; and R2 is a hydrogen atom or an alkyl radical having from 1 to 3 carbon atoms; is heated in the presence of water, in a pressure-resistant vessel, to a temperature in the range from 110 °C to 220 °C and is hydrolyzed.