摘要:
The invention relates to a microorganism which produces and/or secretes an organic chemical compound, wherein the microorganism has an increased expression, in comparison with the respective starting strain, of a polypeptide LpdA having the activity of a transhydrogenase; and also a method for producing an organic chemical compound, using the microorganism according to the invention.
摘要翻译:使用微生物发酵有机化合物的方法包括:(a)产生有机化合物的微生物的发酵,其中微生物在编码多肽的多核苷酸中过表达,所述多核苷酸的氨基酸序列与氨基酸具有至少80%的同一性 SEQ ID NO:2的酸序列,(b)从(a)的发酵液中富集有机化合物,其中未定义的序列可以在ftp://ftp.wipo.int/pub/ 出版-PCT-序列/出版物。
摘要:
The invention relates to an isolated polynucleotide having promoter activity, to a variant of the promoter of the gap gene encoding glyceraldehyde-3-phosphate dehydrogenase, and to a microorganism that produces and/or secretes a fine chemical, wherein the microorganism contains the isolated polynucleotide having promoter activity, which enables the overexpression of different genes compared to the respective starting strain. The invention also relates to a method for producing fine chemicals using the microorganism according to the invention.
摘要:
The invention relates to a microorganism which produces and/or secretes an organo-chemical compound, the microorganism demonstrating an expression of one or more protein subunits of the ABC transporter with the activity of a trehalose importer, which expression is increased in comparison with the respective starting strain, where the microorganism is capable of taking up trehalose from the medium; and to a process for the production of an organo-chemical compound using the microorganism according to the invention, where an accumulation of trehalose in the fermentation broth is reduced or avoided.
摘要:
The object of the invention is a method for manufacturing L-amino acids using coryneform bacteria in which the AmtR regulator has been weakened, and corresponding recombinant bacteria, polynucleotides and vectors.