AMINO SUGAR-CONTAINING GLUCAN, METHOD FOR PRODUCING SAME AND USE OF SAME
    1.
    发明公开
    AMINO SUGAR-CONTAINING GLUCAN, METHOD FOR PRODUCING SAME AND USE OF SAME 审中-公开
    ZUCKERHALTIGES AMINOGLUCAN,VERFAHREN ZU SEINER HERSTELLUNG UND VERWENDUNG DAVON

    公开(公告)号:EP2636748A1

    公开(公告)日:2013-09-11

    申请号:EP11837764.7

    申请日:2011-11-07

    IPC分类号: C12P19/26 A61K47/36 C08B37/00

    摘要: An object of the present invention is to provide a glucosamine-containing glucan, a modified product and a conjugate thereof.
    The glucosamine-containing glucan of the present invention is a glucosamine-containing glucan wherein the glucan has a plurality of non-reducing ends and at least one glucosamine residue is bound via an α-1,4-bond to each of two or more non-reducing ends of the branched α-1,4-glucan, but no glucosamine residue is present at a position other than the non-reducing ends of the branched α-1,4-glucan, wherein the degree of polymerization of the glucan is 15 or more and 4 x 10 5 or less. Theglucosamine-containingglucan of the present invention can be provided by allowing an α-glucan phosphorylase to act on an aqueous solution comprising a branched α-1,4-glucan and glucosamine-1-phosphate.

    摘要翻译: 本发明的目的是提供含有葡糖胺的葡聚糖,其改性产物及其缀合物。 本发明的含葡糖胺的葡聚糖是含有葡糖胺的葡聚糖,其中葡聚糖具有多个非还原性末端,并且至少一个葡糖胺残基通过±-1,4-键与两个或多个非还原末端中的每一个结合, - 分支的±-1,4-葡聚糖的末端,但在支链±-1,4-葡聚糖的非还原性末端以外的位置处不存在葡糖胺残基,其中葡聚糖的聚合度为 15以上且4×10 5以下。 本发明的含有葡糖胺的葡聚糖可以通过使β-葡聚糖磷酸化酶作用于含有支链的±1-1葡聚糖和葡糖胺-1-磷酸的水溶液来提供。

    NON-REDUCING END-MODIFIED GLUCAN, METHOD FOR PRODUCING SAME, AND USE THEREOF
    4.
    发明公开
    NON-REDUCING END-MODIFIED GLUCAN, METHOD FOR PRODUCING SAME, AND USE THEREOF 有权
    NICHTREDUZIERENDES ENDMODIZIFIERTES GLUCAN,VERFAHREN ZU SEINER HERSTELLUNG UND VERWENDUNG DAVON

    公开(公告)号:EP2636749A1

    公开(公告)日:2013-09-11

    申请号:EP11837765.4

    申请日:2011-11-07

    IPC分类号: C12P19/26 A61K47/36 C08B37/00

    摘要: An object of the present invention is to provide a glucan containing at least one residue selected from an N-acetylglucosamine residue and a galactose residue, and a modified product. The branched glucan of the present invention is a branched glucan wherein the branched glucan has a plurality of non-reducing ends and at least one residue selected from an N-acetylglucosamine residue and a galactose residue is bound via an α-1,4-bond to each of two or more non-reducing ends of the branched α-1,4-glucan, but neither an N-acetylglucosamine residue nor a galactose residue is present at the position other than the non-reducing ends of the branched α-1,4-glucan.

    摘要翻译: 本发明的目的是提供一种含有至少一种选自N-乙酰氨基葡萄糖残基和半乳糖残基的残基的葡聚糖和一种改性产物。 本发明的支链葡聚糖是支链葡聚糖,其中支链葡聚糖具有多个非还原性末端,并且至少一个选自N-乙酰氨基葡萄糖残基和半乳糖残基的残基通过±-1,4-键结合 至支链±-1,4-葡聚糖的两个或多个非还原性末端中的每一个,但在支化±1,1-葡聚糖的非还原末端以外的位置处不存在N-乙酰葡糖胺残基和半乳糖残基 1,4-葡聚糖。

    GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME
    6.
    发明公开
    GLUCURONIC ACID-CONTAINING GLUCAN, PROCESS FOR PRODUCTION OF SAME, AND USE OF SAME 有权
    GLUCURONSÄUREHALTIGESGLUCAN,VERFAHREN ZU SEINER HERSTELLUNG UND SEINE VERWENDUNG

    公开(公告)号:EP2428578A1

    公开(公告)日:2012-03-14

    申请号:EP10772125.0

    申请日:2010-05-10

    摘要: An object of the present invention is to provide a uronic acid-containing glucan or a modified product thereof. The glucuronic acid-containing glucan of the present invention is a glucuronic acid-containing glucan in which a glucuronic acid residue is bound to at least one non-reducing end of a glucan, and the glucan is a branched α-1,4 glucan or a linear α-1,4 glucan. The glucuronic acid-containing glucan of the present invention can be provided by allowing α-glucan phosphorylase derived from Aquifex aeolicus VF5 to act on glucuronic acid-1-phosphate to thereby transfer a glucuronic acid residue to the non-reducing end of the receptor glucan.

    摘要翻译: 本发明的目的是提供一种含糖醛酸的葡聚糖或其改性产物。 本发明的含葡萄糖醛酸的葡聚糖是葡萄糖醛酸的葡聚糖,其中葡萄糖醛酸残基与葡聚糖的至少一个非还原末端结合,葡聚糖是支链的±-1,4葡聚糖或 线性±-1,4葡聚糖。 本发明的含葡萄糖醛酸的葡聚糖可以通过使得来自Aquifex aeolicus VF5的±葡聚糖磷酸化酶作用于葡糖醛酸-1-磷酸酯上,从而将葡萄糖醛酸残基转移到受体葡聚糖的非还原末端来提供 。