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公开(公告)号：EP2274297A1
公开(公告)日：2011-01-19
申请号：EP09732665.6
申请日：2009-04-06
发明人： BERTHEL, Steven, Joseph , BRINKMAN, John, A. , HAYDEN, Stuart , HAYNES, Nancy-Ellen , KESTER, Robert, Francis , McDERMOTT, Lee, Apostle , QIAN, Yimin , SARABU, Ramakanth , SCOTT, Nathan, Robert , TILLEY, Jefferson, Wright
IPC分类号： C07D401/12 , C07D403/12 , C07D405/14 , C07D413/14 , C07D417/12 , C07F7/18 , A61K31/41 , A61K31/4155 , A61K31/427 , A61K31/44 , A61K31/497 , A61P3/10
CPC分类号： C07D403/12 , C07D401/12 , C07D405/14 , C07D413/14 , C07D417/12
摘要： Provided herein are compounds of the formula (I): wherein X, R
1 , R
2 and R
3 are as defined in the specification, as well as pharmaceutically acceptable salts thereof. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.摘要翻译： 本文提供式（I）的化合物：其中X，R 1，R 2和R 3如说明书中所定义，及其药学上可接受的盐。 这些化合物和含有它们的药物组合物可用于治疗代谢性疾病和病症，例如II型糖尿病。
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公开(公告)号：EP2274297B1
公开(公告)日：2012-05-09
申请号：EP09732665.6
申请日：2009-04-06
发明人： BERTHEL, Steven, Joseph , BRINKMAN, John, A. , HAYDEN, Stuart , HAYNES, Nancy-Ellen , KESTER, Robert, Francis , McDERMOTT, Lee, Apostle , QIAN, Yimin , SARABU, Ramakanth , SCOTT, Nathan, Robert , TILLEY, Jefferson, Wright
IPC分类号： C07D401/12 , C07D403/12 , C07D405/14 , C07D413/14 , C07D417/12 , C07F7/18 , A61K31/41 , A61K31/4155 , A61K31/427 , A61K31/44 , A61K31/497 , A61P3/10
CPC分类号： C07D403/12 , C07D401/12 , C07D405/14 , C07D413/14 , C07D417/12
摘要： Provided herein are compounds of the formula (I): wherein X, R
1 , R
2 and R
3 are as defined in the specification, as well as pharmaceutically acceptable salts thereof. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
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