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公开(公告)号：EP2344537A1
公开(公告)日：2011-07-20
申请号：EP09736830.2
申请日：2009-10-07
发明人： BAEHNER, Monika , BRINKMANN, ULRICH , GEORGES, Guy , GRIEP, Remko, Albert , IMHOF-JUNG, Sabine , KAVLIE, Anita , KETTENBERGER, Hubert , KLEIN, Christian , REGULA, Joerg, Thomas , SCHEFER, Wolfgang , SCHANZER, Juergen, Michael , SCHEUER, Werner , SEEBER, Stefan , THOMAS, Markus
IPC分类号： C07K16/22 , A61K39/395 , C07K19/00 , C07K16/46 , C07K14/00
CPC分类号： C07K16/22 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/31 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2319/00 , C07K2319/30
摘要： The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
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公开(公告)号：EP2134745A1
公开(公告)日：2009-12-23
申请号：EP08734921.3
申请日：2008-04-01
发明人： BRINKMANN, Ulrich , BRUENKER, Peter , FERRARA KOLLER, Claudia , LANZENDOERFER, Martin , REGULA, Joerg, Thomas , SCHLOTHAUER, Tilman , SEEBER, Stefan , ZECK, Anne
IPC分类号： C07K14/705
CPC分类号： C07K14/70535 , G01N2333/70535
摘要： The present invention relates to the field of human immunoglobulin receptors. It is herein reported the glycostructure of a human Fc gamma receptor HIa recombinantly expressed in human embryonic kidney cells and Chinese hamster ovary cells.
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公开(公告)号：EP3174897A1
公开(公告)日：2017-06-07
申请号：EP15750278.2
申请日：2015-07-29
发明人： IMHOF-JUNG, Sabine , KLEIN, Christian , KLOSTERMANN, Stefan , REGULA, Joerg, Thomas , SCHAEFER,Wolfgang
CPC分类号： C07K16/468 , C07K16/00 , C07K16/22 , C07K16/244 , C07K16/2863 , C07K16/2875 , C07K16/32 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/41 , C07K2317/515 , C07K2317/522 , C07K2317/526 , C07K2317/56 , C07K2317/66 , C07K2317/92 , C07K2317/94
摘要： The present invention relates to multispecific antibodies, methods for their production, pharmaceutical compositions containing said antibodies and uses thereof.
摘要翻译： 本发明涉及多特异性抗体，其制备方法，含有所述抗体的药物组合物及其用途。
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公开(公告)号：EP2344537B1
公开(公告)日：2014-01-29
申请号：EP09736830.2
申请日：2009-10-07
发明人： BAEHNER, Monika , BRINKMANN, Ulrich , GEORGES, Guy , GRIEP, Remko Albert , IMHOF-JUNG, Sabine , KAVLIE, Anita , KETTENBERGER, Hubert , KLEIN, Christian , REGULA, Joerg, Thomas , SCHAEFER, Wolfgang , SCHANZER, Juergen Michael , SCHEUER, Werner , SEEBER, Stefan , THOMAS, Markus
IPC分类号： C07K16/22 , A61K39/395 , C07K19/00 , C07K16/46 , C07K14/00
CPC分类号： C07K16/22 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/31 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2319/00 , C07K2319/30
摘要： The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
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公开(公告)号：EP3174897B1
公开(公告)日：2020-02-12
申请号：EP15750278.2
申请日：2015-07-29
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公开(公告)号：EP2552960B1
公开(公告)日：2018-04-18
申请号：EP11711071.8
申请日：2011-03-24
发明人： BAEHNER, Monika , IMHOF-JUNG, Sabine , KAVLIE, Anita , KETTENBERGER, Hubert , KLEIN, Christian , REGULA, Joerg, Thomas , SCHAEFER, Wolfgang , SCHANZER, Juergen, Michael , SCHEUER, Werner , STUBENRAUCH, Kay-Gunnar , THOMAS, Markus
CPC分类号： C07K16/22 , A61K2039/505 , C07K16/3015 , C07K16/3046 , C07K16/468 , C07K2317/31 , C07K2317/35 , C07K2317/52 , C07K2317/522 , C07K2317/56 , C07K2317/66 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： The present invention relates to bispecific, bivalent antibodies against human vascular endothelial growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
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