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公开(公告)号：EP2134745A1
公开(公告)日：2009-12-23
申请号：EP08734921.3
申请日：2008-04-01
发明人： BRINKMANN, Ulrich , BRUENKER, Peter , FERRARA KOLLER, Claudia , LANZENDOERFER, Martin , REGULA, Joerg, Thomas , SCHLOTHAUER, Tilman , SEEBER, Stefan , ZECK, Anne
IPC分类号： C07K14/705
CPC分类号： C07K14/70535 , G01N2333/70535
摘要： The present invention relates to the field of human immunoglobulin receptors. It is herein reported the glycostructure of a human Fc gamma receptor HIa recombinantly expressed in human embryonic kidney cells and Chinese hamster ovary cells.
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2.发明授权Method for identifying a nucleic acid encoding a hemopexin-like structure which specifically binds a predetermined target molecule. 有权用于鉴定编码具有特异性结合到预定分子血红素结合蛋白样结构的方法Nukeinsäure
公开(公告)号：EP1836223B1
公开(公告)日：2011-11-23
申请号：EP06700410.1
申请日：2006-01-02
CPC分类号： C07K14/47 , C12N9/6491 , C12N15/1034 , C12N15/63 , G01N33/6803
摘要： The invention concerns a method for the generation of a polypeptide with specific binding properties to a predetermined target molecule which are not naturally inherent to that polypeptide. At the same time an optimization of the binding specifity and a process of production are described. The invention further concerns a method for the identification and modification of specific amino acid positions within a polypeptide scaffold.
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3.发明公开CONJUGATES OF THE C DOMAIN OF HUMAN GELATINASE A AND POLYETHYLENE GLYCOL, METHODS OF PURIFICATION AND USES THEREOF 审中-公开C结构域人的缀合物和明胶酶A聚乙二醇，清洗方法和用途
公开(公告)号：EP1482982A1
公开(公告)日：2004-12-08
申请号：EP03743362.0
申请日：2003-02-28
CPC分类号： C12N9/6491 , A61K38/4886 , A61K47/60
摘要： A conjugate comprising the C domain of human gelatinase A (PEX domain, PEX) and one to three poly(ethylene glycol) groups), said poly(ethylene glycol) group(s) having an overall molecular weight of from about 10 to 40 kDa and being conjugated via primary amino group(s) of said PEX is useful for the treatment of cancer.
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