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公开(公告)号：EP3221355B1
公开(公告)日：2020-10-07
申请号：EP15797954.3
申请日：2015-11-16
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公开(公告)号：EP3704155A2
公开(公告)日：2020-09-09
申请号：EP18800545.8
申请日：2018-10-31
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公开(公告)号：EP3221356B1
公开(公告)日：2020-09-02
申请号：EP15797970.9
申请日：2015-11-17
发明人： BACAC, Marina , BRUENKER, Peter , FREIMOSER-GRUNDSCHOBER, Anne , HOSSE, Ralf , KLEIN, Christian , MOESSNER, Ekkehard , UMANA, Pablo , WEINZIERL, Tina
IPC分类号： C07K16/28 , C07K16/46 , A61K39/395 , A61P35/00
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公开(公告)号：EP3186283B1
公开(公告)日：2019-12-25
申请号：EP15753700.2
申请日：2015-08-25
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公开(公告)号：EP3781200A1
公开(公告)日：2021-02-24
申请号：EP19723014.7
申请日：2019-04-16
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6.发明公开
公开(公告)号：EP3455248A1
公开(公告)日：2019-03-20
申请号：EP17725542.9
申请日：2017-05-11
发明人： FERRARA KOLLER, Claudia , CLAUS, Christina , KLEIN, Christian , SEEBER, Stefan , AMANN, Maria , GRAU-RICHARDS, Sandra , BRUENKER, Peter , UMANA, Pablo , LEVITSKI, Viktor , MOESSNER, Ekkehard
IPC分类号： C07K14/705 , A61K39/395 , C07K16/28 , C12N15/62
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公开(公告)号：EP3433280A1
公开(公告)日：2019-01-30
申请号：EP17711223.2
申请日：2017-03-20
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公开(公告)号：EP2992015B1
公开(公告)日：2018-08-29
申请号：EP14721825.9
申请日：2014-04-30
发明人： KLEIN, Christian , LANG, Sabine , POLSON, Andrew , UMANA, Pablo
CPC分类号： C07K16/2887 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6811 , A61K47/6851 , A61K2039/507 , C07K16/2803 , C07K16/2851 , C07K2317/41
摘要： The present invention is directed to the combination therapy of an afucosylated anti-CD20 antibody with a CD22 antibody-drug conjugate for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with an afucosylated humanized B-Ly1 antibody and a CD22 antibody-drug conjugate.
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公开(公告)号：EP3083696B1
公开(公告)日：2018-02-14
申请号：EP14821603.9
申请日：2014-12-18
发明人： CROASDALE, Rebecca , DUERNER, Lydia Jasmin , GEORGES, Guy , HOFER, Thomas , HOSSE, Ralf , KLEIN, Christian , MOESSNER, Ekkehard , MOSER, Samuel , SCHAEFER, Wolfgang , SCHANZER, Juergen Michael , SCHEUER, Werner , SUSTMANN, Claudio , UMANA, Pablo
IPC分类号： C07K16/32 , C07K16/46 , A61K39/395 , A61P35/00
CPC分类号： C07K16/32 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/522 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/64 , C07K2317/66 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/92 , C07K2317/94
摘要： The present invention relates to bispecific HER2 antibodies, novel HER2 antibody variants, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
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公开(公告)号：EP4406607A2
公开(公告)日：2024-07-31
申请号：EP24169799.4
申请日：2019-04-16
发明人： KLEIN, Christian , UMANA, Pablo , HAAS, Alexander , WEISER, Barbara , LIPSMEIER, Florian , GEORGES, Guy , FENN, Sebastian , MOELLEKEN, JOERG , MATSCHEKO, Daniela , BORMANN, Felix
IPC分类号： A61P35/00
CPC分类号： C07K16/2887 , C07K16/3007 , C07K16/32 , C07K16/44 , C07K2317/2420130101 , C07K2317/3120130101 , C07K2317/3420130101 , C07K2317/5220130101 , C07K2317/6420130101 , C07K2317/9220130101 , C07K2317/9420130101 , A61K39/39558 , A61K51/0495 , A61K51/109 , A61K51/1096 , A61K2039/50520130101 , A61K2039/54520130101 , A61P35/00
摘要： The present application relates to antibodies which bind specifically to chelated radionuclides, including bispecific antibodies. It further relates to the use of such bispecific antibodies in applications such as radioimmunoimaging and radioimmunotherapy. It additionally relates to clearing agents and compositions useful in such methods.
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