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1.BENZIMIDAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS FXR AGONISTS AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME 审中-公开
标题翻译: 苯并咪唑衍生物,PROCESS所周之,它们作为FXR激动剂和含筹备PHARAMZEUTISCHE公开(公告)号:EP2038259A1
公开(公告)日:2009-03-25
申请号:EP07765461.4
申请日:2007-06-18
发明人: BENSON, Gregory Martin , BLEICHER, Konrad , CHUCHOLOWSKI, Alexander , DEHMLOW, Henrietta , GRETHER, Uwe , KUHN, Bernd , MARTIN, Rainer E. , NIESOR, Eric J. , PANDAY, Narendra , RICHTER, Hans , SCHULER, Franz , WAROT, Xavier Marie , WRIGHT, Matthew , YANG, Minmin
IPC分类号: C07D235/18 , C07D409/10 , C07D409/04 , C07D403/04 , C07D403/10 , A61K31/4184 , A61P3/00 , A61P25/00 , A61P35/00
CPC分类号: C07D235/18 , C07D235/02 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/04 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/10 , C07D413/04 , C07D417/06
摘要: The invention is concerned with novel benzimidazole derivatives of formula (I) wherein R1 to R8 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to FXR and can be used as medicaments.