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公开(公告)号：EP2513103A1
公开(公告)日：2012-10-24
申请号：EP10792890.5
申请日：2010-12-13
发明人： BERTHEL, Steven Joseph , CHEN, Li , CORBETT, Wendy Lea , FENG, Lichun , HAYNES, Nancy-Ellen , KESTER, Robert Francis , SO, Sung-Sau , TILLEY, Jefferson Wright
IPC分类号： C07D471/04 , A61K31/437
CPC分类号： C07D471/04 , C07C2601/04 , C07C2601/06 , C07D401/06 , C07D403/10 , C07D405/06
摘要： Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
摘要翻译： 本文提供了式（I）化合物：及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗代谢性疾病和病症，例如II型糖尿病。
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公开(公告)号：EP2964633A1
公开(公告)日：2016-01-13
申请号：EP14707400.9
申请日：2014-03-03
发明人： BERTHEL, Steven Joseph , CHEN, Zhi , CHI, Feng , CHIN, Elbert , ERICKSON, Shawn David , GABRIEL, Stephen Deems , KOCER, Buelent , MERTZ, Eric , PLANCHER, Jean-Marc , WEIKERT, Robert J.
IPC分类号： C07D403/12 , C07D401/12 , C07D409/12 , C07D487/10 , A61K31/4196 , A61P31/12
CPC分类号： C07D401/12 , A61K31/4196 , A61K31/437 , A61K31/4439 , A61K31/496 , A61K31/501 , A61K31/506 , A61K38/21 , A61K45/06 , C07D249/14 , C07D403/12 , C07D409/12 , C07D471/04 , C07D487/10
摘要： The present invention discloses compounds of Formula (I): wherein the variables in Formula (I) are defined as described herein. Also disclosed are pharmaceutical compositions containing such compounds and methods for using the compounds of Formula (I) in the prevention or treatment of HCV infection.
摘要翻译： 本发明公开了式（I）的化合物：其中式（I）中的变量如本文所述定义。 还公开了含有这些化合物的药物组合物以及使用式（I）化合物预防或治疗HCV感染的方法。
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公开(公告)号：EP1934199B1
公开(公告)日：2009-04-22
申请号：EP06793670.8
申请日：2006-09-20
发明人： BERTHEL, Steven Joseph , ERICKSON, Shawn David , FOTOUHI, Nader , KESTER, Robert Francis , KIM, Kyungjin , MISCHKE, Steven Gregory , QIAN, Yimin , THAKKAR, Kshitij Chhabilbhai , TILLEY, Jefferson Wright , WANG, Hong
IPC分类号： C07D401/06
CPC分类号： C07D401/04 , C07D401/14 , C07D471/04
摘要： Provided herein are compounds of the formula (I): wherein A, R1, R2, R4, Ra and Rb are as those disclosed in the specification, as well as pharmaceutically acceptable salts thereof. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of obesity, hyperphagia, anxiety, depression and related disorders and diseases.
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公开(公告)号：EP1934199A2
公开(公告)日：2008-06-25
申请号：EP06793670.8
申请日：2006-09-20
发明人： BERTHEL, Steven Joseph , ERICKSON, Shawn David , FOTOUHI, Nader , KESTER, Robert Francis , KIM, Kyungjin , MISCHKE, Steven Gregory , QIAN, Yimin , THAKKAR, Kshitij Chhabilbhai , TILLEY, Jefferson Wright , WANG, Hong
IPC分类号： C07D401/06
CPC分类号： C07D401/04 , C07D401/14 , C07D471/04
摘要： Provided herein are compounds of the formula (I): wherein A, R1, R2, R4, Ra and Rb are as those disclosed in the specification, as well as pharmaceutically acceptable salts thereof. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of obesity, hyperphagia, anxiety, depression and related disorders and diseases.
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