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1.发明公开7-OXO-4,7 -DIHYDRO- PYRAZOLO [1, 5 -A]PYRIMIDINE DERIVATIVES WHICH ARE USEFUL IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE 审中-公开7-氧代-4,7-二氢[1,5-A]其中治疗，病毒疾病或救济预防是USED嘧啶衍生物
公开(公告)号：EP2861232A1
公开(公告)日：2015-04-22
申请号：EP13730131.3
申请日：2013-05-23
发明人： WOLKERSTORFER, Andrea , SZOLAR, Oliver , HANDLER, Norbert , CUSACK, Stephen , SAUVAÎTRE, Thibault , MICHAUT-SIMON, Céline , MORICE, Christophe , GIETHLEN, Bruno , LANGER, Thierry , SMITH, Mark , SO, Sung-Sau , CLASSEN-HOUBEN, Dirk , BUSCHMANN, Helmut
IPC分类号： A61K31/519 , A61P31/12 , A61P31/16
CPC分类号： A61K31/519 , A61K31/437 , A61K31/496 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D487/04 , C07D513/04
摘要： The present invention relates to a compound having the general formula (C), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, codrug, cocrystal, prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.
摘要翻译： 本发明涉及具有通式（C），任选地在药学上可接受的盐，溶剂合物，多晶型物，共药物，共结晶体，前药，互变异构体，外消旋体，对映异构体，或非对映体或混合物的形式存在的化合物，这是有用 治疗，改善或预防的病毒性疾病。 进一步，特定的组合疗法是游离缺失盘。
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2.发明授权PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE 有权嘧啶-4- ON衍生物及其在治疗，减轻或预防一种疾病病毒的
公开(公告)号：EP2794616B1
公开(公告)日：2016-06-29
申请号：EP12787384.2
申请日：2012-10-19
发明人： CLASSEN-HOUBEN, Dirk , WOLKERSTORFER, Andrea , SZOLAR, Oliver , SMITH, Mark , SO, Sung-Sau , CUSACK, Stephen , LANGER, Thierry , GIETHLEN, Bruno , MORICE, Christophe , MICHAUT-SIMON, Céline , JUNG, Laurence
IPC分类号： C07D495/04 , A61K31/519 , A61P31/12
CPC分类号： C07D495/04 , A61K31/519 , A61K31/5377 , A61K45/06
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3.发明公开7-OXO-THIAZOLOPYRIDINE CARBONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE 有权7-氧代THIAZOLOPYRIDINKOHLENSÄUREDERIVATE及其用途用于治疗，减轻或预防一种疾病病毒的
公开(公告)号：EP2864338A2
公开(公告)日：2015-04-29
申请号：EP13730130.5
申请日：2013-05-23
申请人： Savira Pharmaceuticals GmbH , F.Hoffmann-La Roche AG , European Molecular Biology Laboratory (EMBL)
发明人： WOLKERSTORFER, Andrea , SZOLAR, Oliver , HANDLER, Norbert , CUSACK, Stephen , SAUVAÎTRE, Thibault , MICHAUT-SIMON, Céline , MORICE, Christophe , GIETHLEN, Bruno , LANGER, Thierry , SMITH, Mark , SO, Sung-Sau , CLASSEN-HOUBEN, Dirk , BUSCHMANN, Helmut
IPC分类号： C07D513/04 , A61K31/429 , A61P31/12
CPC分类号： C07D513/04 , A61K31/437 , A61K31/4545 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K45/06 , C07D487/04
摘要： The present invention relates to a compound having the general formula (A), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, codrug, cocrystal, prodrug, tautomer, racemate, enantiomer, or diasiereomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.
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4.发明公开HETEROARYL HYDROXAMIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE 审中-公开HETEROARYLHYDROXAMSÄUREDERIVATE及其用途用于治疗，减轻或预防疾病病毒的
公开(公告)号：EP2776396A2
公开(公告)日：2014-09-17
申请号：EP12786860.2
申请日：2012-10-19
发明人： CLASSEN-HOUBEN, Dirk , WOLKERSTORFER, Andrea , SZOLAR, Oliver , SMITH, Mark , SO, Sung-Sau , CUSACK, Stephen , LANGER, Thierry , GIETHLEN, Bruno , MORICE, Christophe , MICHAUT-SIMON, Céline , ZUBIETA, Chloe
IPC分类号： C07D213/81 , C07D217/26 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/08 , C07D413/04 , C07D471/04 , C07D495/04 , A61K31/44 , A61P31/16
CPC分类号： C07D213/81 , A61K31/44 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/47 , A61K31/472 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K45/06 , C07D215/48 , C07D217/26 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/08 , C07D413/04 , C07D471/04 , C07D493/10 , C07D495/04
摘要： The present invention relates to a compound having the general formula I, optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, tautomer, racemate, enantiomer, or dsasiereomer or mixture thereof, which is useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.
摘要翻译： 本发明涉及具有通式I，任选呈其药学上可接受的盐，溶剂合物，多晶型物，前药，互变异构体，外消旋体，对映体，或对映异构体或其混合物的形式，其可用于治疗，改善或预防有用的化合物，在所有 病毒性疾病。 进一步，特定的组合疗法是游离缺失盘。
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5.发明授权7-OXO-THIAZOLOPYRIDINE CARBONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE 有权7-氧代THIAZOLOPYRIDINKOHLENSÄUREDERIVATE及其用途用于治疗，减轻或预防一种疾病病毒的
公开(公告)号：EP2864338B1
公开(公告)日：2016-12-14
申请号：EP13730130.5
申请日：2013-05-23
申请人： Savira Pharmaceuticals GmbH , F.Hoffmann-La Roche AG , European Molecular Biology Laboratory (EMBL)
发明人： WOLKERSTORFER, Andrea , SZOLAR, Oliver , HANDLER, Norbert , CUSACK, Stephen , SAUVAÎTRE, Thibault , MICHAUT-SIMON, Céline , MORICE, Christophe , GIETHLEN, Bruno , LANGER, Thierry , SMITH, Mark , SO, Sung-Sau , CLASSEN-HOUBEN, Dirk , BUSCHMANN, Helmut
IPC分类号： C07D513/04 , A61K31/429 , A61P31/12
CPC分类号： C07D513/04 , A61K31/437 , A61K31/4545 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K45/06 , C07D487/04
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6.发明公开PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE 有权嘧啶-4- ON衍生物及其在治疗，减轻或预防一种疾病病毒的
公开(公告)号：EP2794616A1
公开(公告)日：2014-10-29
申请号：EP12787384.2
申请日：2012-10-19
发明人： CLASSEN-HOUBEN, Dirk , WOLKERSTORFER, Andrea , SZOLAR, Oliver , SMITH, Mark , SO, Sung-Sau , CUSACK, Stephen , LANGER, Thierry , GIETHLEN, Bruno , MORICE, Christophe , MICHAUT-SIMON, Céline , JUNG, Laurence
IPC分类号： C07D495/04 , A61K31/519 , A61P31/12
CPC分类号： C07D495/04 , A61K31/519 , A61K31/5377 , A61K45/06
摘要： The present invention relates to a compound having the general formula (II), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, Formula (II) which is useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.
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