-
公开(公告)号：EP0788511B1
公开(公告)日：2002-12-11
申请号：EP95932935.0
申请日：1995-09-29
-
公开(公告)号：EP1157022A1
公开(公告)日：2001-11-28
申请号：EP00902929.9
申请日：2000-02-14
发明人： TOMISHIMA, Masaki , TAKE, Kazuhiko
IPC分类号： C07D417/04 , C07D417/06 , C07D417/12 , C07D401/04 , C07D213/58 , C07D213/61 , C07D213/73 , C07D213/63 , C07D213/85 , A61K31/426 , A61K31/4427 , A61K31/44
CPC分类号： C07D401/04 , C07D213/58 , C07D213/61 , C07D213/63 , C07D213/73 , C07D213/85 , C07D417/04 , C07D417/06 , C07D417/12
摘要： A compound of formula (I) wherein each symbol is as defined in the specification, and pharmaceutically acceptable salts thereof. The compound (I) of the present invention and pharmaceutically acceptable salts thereof possess a strong inhibitory activity on the production of nitric oxide (NO), and are useful for prevention and/or treatment of NOS(nitric oxide synthase)-mediated diseases such as adult respiratory distress syndrome, myocarditis, synovitis, septic shock, insulin-dependent diabetes mellitus, ulcerative colitis, cerebral infarction, rheumatoid arthritis, osteoarthritis, osteoporosis, systemic lupus erythematosus, rejection by organ transplantation, asthma, pain, ulcer, and the like in human being and animals.
-
公开(公告)号：EP0941236A1
公开(公告)日：1999-09-15
申请号：EP97912494.0
申请日：1997-11-18
摘要： This invention relates to new polypeptide compounds represented by general formula (I), wherein R?1 and R2¿ are as defined in the description and pharmaceutically acceptable salt thereof which have antimicrobial activities (especially antifungal activities), inhibitory activity on β-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for the prophylactic and/or therapeutic treatment of infectious disease including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia in a human being or an animal.
-
公开(公告)号：EP0788511A1
公开(公告)日：1997-08-13
申请号：EP95932935.0
申请日：1995-09-29
摘要： This invention relates to new polypeptide compounds represented by formula (I), wherein R1 is as defined in the description and pharmaceutically acceptable salt thereof which have antimicrobial activities (especially, antifungal activities), inhibitory activity on β-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for the prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.
-
-
-
搜索结果
4 条记录 (耗时 0.018 秒)
