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1.发明公开
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公开(公告)号：EP3856887A1
公开(公告)日：2021-08-04
申请号：EP19783227.2
申请日：2019-09-23
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3.发明授权VERKAPSELUNGSEINRICHTUNG UND -VERFAHREN ZUR VERKAPSELUNG EINER PROBE IN EINER POLYMERKAPSEL 有权封装装置和用于将样品封装在聚合物胶囊中的方法
公开(公告)号：EP3024567B1
公开(公告)日：2017-10-11
申请号：EP14733527.7
申请日：2014-06-27
发明人： ZIMMERMANN, Heiko , NEUBAUER, Julia
CPC分类号： C12N11/04 , A61K2035/128 , B01J13/14 , B01J13/206 , C12M25/01 , C12N11/10
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4.发明公开
公开(公告)号：EP3894076A1
公开(公告)日：2021-10-20
申请号：EP19832849.4
申请日：2019-12-10
发明人： ZIMMERMANN, Heiko , NEUBAUER, Julia , MEISER, Ina , GEPP, Michael
IPC分类号： B01L3/00
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公开(公告)号：EP3849777A1
公开(公告)日：2021-07-21
申请号：EP19758985.6
申请日：2019-08-28
IPC分类号： B29C64/106 , B29C64/364 , B33Y10/00 , B33Y30/00 , A61L27/52 , C12N5/00
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6.发明公开KULTIVIERUNGSGEFÄß UND VERFAHREN ZUR KULTIVIERUNG BIOLOGISCHER ZELLEN IN HÄNGENDEN TROPFEN 审中-公开生物细胞的悬滴培养培养容器和方法
公开(公告)号：EP3019586A1
公开(公告)日：2016-05-18
申请号：EP14738380.6
申请日：2014-06-25
摘要： A culture vessel (100), which is designed for culturing biological cells (1) in hanging drops (2), comprises a vessel wall (10), which has a cover portion (11) and a floor portion (12), wherein the cover portion (11) is designed to provide a culturing surface (13), and the floor portion (12) is designed to receive a liquid (3), the vessel wall (10) encloses an interior (20) of the culture vessel on all sides, the culturing surface (13) has holding elements (14), which are designed to position the drops (2), wherein the culturing surface (13) can receive the drops (2) hanging freely in the interior (20), and the vessel wall (10) is movable such that the holding elements (14) can be wetted with the liquid (3) from the floor portion (12). A method for culturing biological cells (1) in hanging drops (2) in the culture vessel (100) is also described.
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公开(公告)号：EP3623136A1
公开(公告)日：2020-03-18
申请号：EP18194428.1
申请日：2018-09-14
IPC分类号： B29C64/106 , B29C64/364 , B33Y10/00 , B33Y30/00 , A61L27/52 , C12N5/00
摘要： The invention relates to a method for producing three-dimensional, preferably porous, hydrogel structures (1) by means of layer build-up technique, wherein the method comprises the following steps. Providing (S1) of a liquid hydrogel solution, preferably a liquid alginate solution, and a, preferably transportable, sample carrier. Layerwise applying (S2) the liquid hydrogel solution onto the sample carrier (4) in a temperature environment, the temperature of which is below the freezing point of the hydrogel solution, to produce a frozen 3D layered hydrogel structure (1a). In order to increase advantageously the porosity of the 3D layered hydrogel structure (1a), i.e. the proportion of small voids, cavities and/or depressions in the 3D layered hydrogel structure, the method according to the invention further comprises the step of drying (S3) of the frozen 3D layered hydrogel structure (1a), e.g. by means of freeze-drying, to produce a porous 3D hydrogel structure (1). The invention relates further also to a device (10) for the layerwise building-up of three-dimensional hydrogel structures.
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9.发明公开SUBSTRATEINRICHTUNG, KONSERVIERUNGSGERÄT UND VERFAHREN ZUR KRYOKONSERVIERUNG EINER BIOLOGISCHEN PROBE 审中-公开基金会，康奈尔韦格里奇，维尔福伦·祖尔·克朗诺维尔·埃因生物科学研究所
公开(公告)号：EP2870230A1
公开(公告)日：2015-05-13
申请号：EP13736765.2
申请日：2013-07-01
IPC分类号： C12M1/00
摘要： The invention relates to a substrate unit (100), in particular for the cryopreservation of a biological sample (1) containing biological cells (2, 2.1, 2.2), comprising a substrate platform (10) having a front side and a back side, wherein the front side of the substrate platform (10) has a cultivation surface (11) for receiving the biological sample (1), a first chamber (20), which comprises the cultivation surface (11) of the substrate platform (10), wherein the first chamber (20) is configured for receiving a cultivation liquid (3), a second chamber (30), which is configured for receiving a temperature control medium (5), and a chamber bracket (50) for receiving the substrate unit (100) in a cryopreservation device in a pivotable manner, wherein the first chamber (20) and the second chamber (30) are connected to each other in an adjacent manner, and the substrate platform (10) forms a separating wall between the first chamber (20) and the second chamber (30), and wherein the back side of the substrate platform (10) faces the second chamber (30). The invention further relates to a cryopreservation device (200), in which the substrate unit (100) is arranged in rotatable manner, and a method for the cryopreservation of a biological sample (1).
摘要翻译： 本发明涉及一种底物单元（100），特别是用于冷冻保存含有生物细胞（2,2,1,2.2）的生物样品（1）的底物单元（100），其包含具有前侧和后侧的基底平台（10） 其特征在于，所述基板平台（10）的前侧具有用于容纳所述生物样品（1）的培养表面（11），包括所述基板平台（10）的培养表面（11）的第一室（20） 其中，所述第一室（20）构造成用于接纳培养液（3），构造成用于接收温度控制介质（5）的第二室（30），以及用于接收所述基板单元 （100）以可枢转的方式在冷冻保存装置中，其中所述第一室（20）和所述第二室（30）以相邻的方式彼此连接，并且所述基板平台（10）在所述第一室 室（20）和第二室（30），并且其中后壁 de（10）面向第二室（30）。 本发明还涉及一种其中衬底单元（100）以可旋转的方式布置的冷冻保存装置（200）和用于生物样品（1）的低温保存的方法。
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10.发明授权
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