专利检索 ap:("G.D. Searle & Co.") AND inv:"GORDON, Gary, B." 第 1 页

1.

发明公开
METHOD OF USING CYCLOOXYGENASE-2 INHIBITORS IN THE TREATMENT AND PREVENTION OF NEOPLASIA 失效
标题翻译：环氧化酶-2抑制剂，用于治疗用途及肿瘤的挠曲

公开(公告)号：EP0932402A1

公开(公告)日：1999-08-04

申请号：EP97911746.0

申请日：1997-10-14

申请人： G.D. SEARLE & CO.

发明人： SEIBERT, Karen , MASFERRER, Jaime , GORDON, Gary, B.

IPC分类号： C07D , C07D233 , A61K31 , A61K45 , A61P35 , A61P43 , C07D213 , C07D231 , C07D261 , C07D263 , C07D277 , C07D401 , C07D417

CPC分类号： A61K31/635 , A61K31/10 , A61K31/18 , A61K31/415 , A61K31/4164 , A61K31/4178 , A61K31/42 , A61K31/421 , A61K31/426 , A61K31/4418 , A61K31/4439

摘要： This invention relates to the use of cyclooxygenase-2 inhibitors or derivatives thereof in preventing and treating neoplasia. In particular, the invention describes the method of preventing and treating epithelial cell neoplasia in a subject, said method comprising treating the subject with a therapeutically-effective amount of a compound of Formula (I) wherein A, R?2 and R3¿ are as described in the specification.

2.

发明公开
USE OF AN INTEGRIN ANTAGONIST AND A CHEMOTHERAPEUTIC AGENT IN THE TREATMENT OF NEOPLASIA 审中-公开
标题翻译：甲整连同CHEMO治疗剂在治疗肿瘤的用途

公开(公告)号：EP1161280A1

公开(公告)日：2001-12-12

申请号：EP00914580.6

申请日：2000-03-01

申请人： G.D. Searle & Co.

发明人： CUNNINGHAM, Jay , GORDON, Gary, B. , NICKOLS, G., Allen , WESTLIN, William, F. , ROGERS, Thomas, E. , RUMINSKI, Peter, G.

IPC分类号： A61P35/00 , A61K31/505 , A61K33/24 , A61K31/675 , A61K31/704 , A61K31/335

CPC分类号： A61K31/704 , A61K31/505 , A61K31/675 , A61K33/24 , C07D239/14 , A61K31/70 , A61K31/335 , A61K2300/00

摘要： The present invention is directed to compounds of formula (I) and pharmaceutically acceptable salts and isomers thereof administered in combination with chemotherapeutic agents.