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2 条记录 (耗时 0.009 秒)

    IMAGING FIBROSIS
    1.
    发明公开
    IMAGING FIBROSIS 审中-公开
    BILDGEBUNG VON FIBROSE

    公开(公告)号：EP2866842A1

    公开(公告)日：2015-05-06

    申请号：EP13732924.9

    申请日：2013-06-28

    申请人： GE Healthcare Limited

    发明人： OLSSON, Andreas ,  ACHANATH, Radha ,  IVESON, Peter, Brian ,  TUCH, David

    IPC分类号： A61K51/04

    CPC分类号： A61K51/0478 ,  A61K2123/00 ,  C07F5/025

    摘要： The present invention provides a labelled compound suitable for use as an
    in vivo imaging agent. The
    in vivo imaging agent of the invention is useful in the
    in vivo diagnosis and imaging of fibrosis and in particular fibrosis in the liver. Also provided by the present invention is a method for the preparation of the labelled compound of the invention and a precursor compound useful in said method and a kit useful for carrying out said method. In addition, the present invention provides a pharmaceutical composition comprising the labelled compound of the invention as well as a method of
    in vivo imaging using the labelled compound of the invention, preferably as the pharmaceutical composition of the invention.

    摘要翻译： 本发明提供了适合用作体内显像剂的标记化合物。 本发明的体内显像剂可用于肝纤维化，特别是纤维化的体内诊断和成像。 本发明还提供了制备本发明的标记化合物的方法和可用于所述方法的前体化合物和用于实施所述方法的试剂盒。 此外，本发明提供了包含本发明的标记化合物的药物组合物以及优选作为本发明的药物组合物的本发明的标记化合物的体内成像方法。