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公开(公告)号：EP4360646A3
公开(公告)日：2024-05-15
申请号：EP23209560.4
申请日：2016-09-23
发明人： GROGAN, Jane L. , JOHNSTON, Robert J. , WU, Yan , LIANG, Wei-Ching , LUPARDUS, Patrick , YADAV, Mahesh , SESHASAYEE, Dhaya , HAZEN, Meredith
IPC分类号： C07K16/28 , A61K39/00 , A61K38/17 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/02 , A61P37/04 , A61P43/00
CPC分类号： A61K2039/50520130101 , C07K2317/3320130101 , C07K2317/3420130101 , C07K2317/7020130101 , C07K2317/9020130101 , C07K16/28 , A61K38/177 , C07K2317/9220130101 , C07K2317/7620130101 , C07K2317/9420130101 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/02 , A61P37/04 , A61P43/00 , Y02A50/30
摘要： The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号：EP3191518A1
公开(公告)日：2017-07-19
申请号：EP15767037.3
申请日：2015-09-11
申请人： Genentech, Inc.
发明人： LEONG, Steven R. , POLSON, Andrew , POLAKIS, Paul , WU, Yan , LIANG, Wei-Ching , FIRESTEIN, Ron
CPC分类号： C07K16/2827 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , A61K47/6803 , A61K47/6809 , A61K47/6855 , A61K47/6869 , A61K2039/505 , C07K16/3015 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/57492
摘要： The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
摘要翻译： 本发明提供了抗B7-H4抗体和免疫缀合物及其使用方法。
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3.发明授权BINDING POLYPEPTIDES WITH DIVERSIFIED AND CONSENSUS VH/VL HYPERVARIABLE SEQUENCES 有权结合多肽具有多样化和共识的VH / VL高变序列
公开(公告)号：EP1957531B1
公开(公告)日：2016-04-13
申请号：EP06837138.4
申请日：2006-11-07
申请人： Genentech, Inc.
发明人： DENNIS, Mark , LIANG, Wei-Ching , WU, Yan
CPC分类号： C07K16/005 , C07K16/32 , C07K2317/21 , C07K2317/24 , C07K2317/56
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公开(公告)号：EP3191518B1
公开(公告)日：2020-01-15
申请号：EP15767037.3
申请日：2015-09-11
申请人： Genentech, Inc.
发明人： LEONG, Steven R. , POLSON, Andrew , POLAKIS, Paul , WU, Yan , LIANG, Wei-Ching , FIRESTEIN, Ron
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公开(公告)号：EP3080164B1
公开(公告)日：2019-01-16
申请号：EP14824269.6
申请日：2014-12-12
申请人： Genentech, Inc.
发明人： YU, Shang-Fan , LIANG, Wei-Ching , WU, Yan , LEONG, Steven , POLSON, Andrew
IPC分类号： C07K16/28 , A61K39/395 , A61P35/02
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公开(公告)号：EP3353210A2
公开(公告)日：2018-08-01
申请号：EP16775058.7
申请日：2016-09-23
发明人： GROGAN, Jane, L. , JOHNSTON, Robert, J. , WU, Yan , LIANG, Wei-Ching , LUPARDUS, Patrick , YADAV, Mahesh , SESHASAYEE, Dhaya , HAZEN, Meredith
CPC分类号： C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/567 , C07K2317/70 , C07K2317/75 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , Y02A50/466
摘要： The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号：EP2200700A1
公开(公告)日：2010-06-30
申请号：EP08834260.5
申请日：2008-09-25
申请人： Genentech, Inc.
发明人： LIANG, Wei-Ching , PLOWMAN, Gregory D. , WU, Yan , YE, Weilan
CPC分类号： C07K16/2842 , A61K2039/505 , A61K2039/507 , C07K2317/24 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to the use of VEGF antagonists and a novel anti-α5β1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-α5β1 antibodies and methods of making and using them.
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公开(公告)号：EP1648939A2
公开(公告)日：2006-04-26
申请号：EP04779660.2
申请日：2004-07-30
申请人： GENENTECH, INC.
发明人： FUH, Germaine , GERBER, Hanspeter , LIANG, Wei-Ching , FELLOUSE, Frederic, A. , SIDHU, Sachdev, S. , WIESMANN, Christian
CPC分类号： C07K16/22 , A61K2039/505 , C07K16/005 , C07K16/32 , C07K2317/24 , C07K2317/31 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , G01N33/6845
摘要： Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding and other biological activities. Further contemplated are uses of the synthetic antibodies in research, diagnostic and therapeutic applications.
摘要翻译： 公开了抗VEGF抗体及其变体，包括对VEGF结合具有高亲和力的抗体。 还提供了使用噬菌体展示技术与初始文库产生和选择具有期望的结合和其他生物活性的抗VEGF抗体的方法。 进一步考虑的是合成抗体在研究，诊断和治疗应用中的用途。
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公开(公告)号：EP4360646A2
公开(公告)日：2024-05-01
申请号：EP23209560.4
申请日：2016-09-23
发明人： GROGAN, Jane L. , JOHNSTON, Robert J. , WU, Yan , LIANG, Wei-Ching , LUPARDUS, Patrick , YADAV, Mahesh , SESHASAYEE, Dhaya , HAZEN, Meredith
IPC分类号： A61K39/00
CPC分类号： A61K2039/50520130101 , C07K2317/3320130101 , C07K2317/3420130101 , C07K2317/7020130101 , C07K2317/9020130101 , C07K16/28 , A61K38/177 , C07K2317/9220130101 , C07K2317/7620130101 , C07K2317/9420130101 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/02 , A61P37/04 , A61P43/00 , Y02A50/30
摘要： The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号：EP3693391A1
公开(公告)日：2020-08-12
申请号：EP19219511.3
申请日：2015-09-11
申请人： Genentech, Inc.
发明人： ZHENG, Bing , POLSON, Andrew , CHIU, Cecilia , LIANG, Wei-Ching , WU, Yan
摘要： Provision of anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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