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公开(公告)号：EP1333094B1
公开(公告)日：2012-04-04
申请号：EP03075454.3
申请日：1997-10-01
发明人： Cech, Thomas R. , Lingner, Joachim , Nakamura, Toru , Chapman, Karen B. , Morin, Gregg B. , Harley, Calvin B. , Andrews, William H., c/o Serra Sciences, Inc.
CPC分类号： C12N15/113 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00 , C07K2319/00 , C12N9/1241 , C12N9/1276 , C12N15/1137 , C12N2310/15 , C12N2310/315 , C12Y207/07049 , Y10S530/827 , Y10S530/828
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公开(公告)号：EP1783139B8
公开(公告)日：2009-09-23
申请号：EP06117664.0
申请日：1997-10-01
发明人： Cech, Thomas R , Lingner, Joachim , Nakamura, Toru , Chapman, Karen B. , Morin, Gregg, B , Harley, Calvin B. , Andrews, William H.
IPC分类号： C07K4/12
CPC分类号： C12N15/113 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00 , C07K2319/00 , C12N9/1241 , C12N9/1276 , C12N15/1137 , C12N2310/15 , C12N2310/315 , C12Y207/07049 , Y10S530/827 , Y10S530/828
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公开(公告)号：EP2213740A1
公开(公告)日：2010-08-04
申请号：EP09176870.5
申请日：1997-10-01
发明人： Cech, Thomas R. , Lingner, Joachim , Nakamura, Toru , Chapman, Karen B. , Morin, Gregg B. , Harley, Calvin B. , Andrews, William H.
IPC分类号： C12N15/54 , C12N9/12 , C12Q1/68 , C12Q1/48 , C12N15/11 , C12N15/85 , A01K67/027 , C07K16/40 , A61K38/45 , A61K31/70 , C12N1/21 , C12N1/19
CPC分类号： C12N15/113 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00 , C07K2319/00 , C12N9/1241 , C12N9/1276 , C12N15/1137 , C12N2310/15 , C12N2310/315 , C12Y207/07049 , Y10S530/827 , Y10S530/828
摘要： The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers.
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公开(公告)号：EP1333094A3
公开(公告)日：2005-02-09
申请号：EP03075454.3
申请日：1997-10-01
发明人： Cech, Thomas R. , Lingner, Joachim , Nakamura, Toru , Chapman, Karen B. , Morin, Gregg B. , Harley, Calvin B. , Andrews, William H., c/o Serra Sciences, Inc.
IPC分类号： C12N15/54 , C12N9/12 , C12Q1/68 , C12Q1/48 , C12N15/11 , C12N15/85 , A01K67/027 , C07K16/40 , A61K38/45 , A61K31/70 , C12N1/21 , C12N1/19 , G01N33/50 , A61P35/00 , A61P43/00
CPC分类号： C12N15/113 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00 , C07K2319/00 , C12N9/1241 , C12N9/1276 , C12N15/1137 , C12N2310/15 , C12N2310/315 , C12Y207/07049 , Y10S530/827 , Y10S530/828
摘要： The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers.
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公开(公告)号：EP0841396B2
公开(公告)日：2012-04-11
申请号：EP97307757.1
申请日：1997-10-01
发明人： Cech, Thomas R. , Lingner, Joachim , Nakamura, Toru , Chapman, Karen B. , Morin, Cregg B. , Harley, Calvin B. , Andrews, William H.
IPC分类号： C12N15/54 , C12N9/12 , C12Q1/68 , C12Q1/48 , C12N15/11 , C12N15/85 , A01K67/027 , C07K16/40 , A61K38/45 , A61K31/70 , C12N1/21 , C12N1/19
CPC分类号： C12N15/113 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00 , C07K2319/00 , C12N9/1241 , C12N9/1276 , C12N15/1137 , C12N2310/15 , C12N2310/315 , C12Y207/07049 , Y10S530/827 , Y10S530/828
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公开(公告)号：EP1783139A2
公开(公告)日：2007-05-09
申请号：EP06117664.0
申请日：1997-10-01
申请人： GERON CORPORATION
发明人： Cech, Thomas R , Lingner, Joachim , Nakamura, Toru , Chapman, Karen B. , Morin, Gregg, B , Harley, Calvin B. , Andrews, William H.
IPC分类号： C07K4/12
CPC分类号： C12N15/113 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00 , C07K2319/00 , C12N9/1241 , C12N9/1276 , C12N15/1137 , C12N2310/15 , C12N2310/315 , C12Y207/07049 , Y10S530/827 , Y10S530/828
摘要： The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of disease such as cancers.
摘要翻译： 本发明提供了与人端粒酶逆转录酶（hTRT）（人端粒酶的催化蛋白亚基）有关的组合物和方法。 本发明的多核苷酸和多肽可用于人类疾病的诊断，预后和治疗，用于改变细胞和生物体的增殖能力，以及用于鉴定和筛选用于治疗疾病如癌症的化合物和治疗。
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7.发明公开
公开(公告)号：EP1333094A2
公开(公告)日：2003-08-06
申请号：EP03075454.3
申请日：1997-10-01
发明人： Cech, Thomas R. , Lingner, Joachim , Nakamura, Toru , Chapman, Karen B. , Morin, Gregg B. , Harley, Calvin B. , Andrews, William H.
CPC分类号： C12N15/113 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00 , C07K2319/00 , C12N9/1241 , C12N9/1276 , C12N15/1137 , C12N2310/15 , C12N2310/315 , C12Y207/07049 , Y10S530/827 , Y10S530/828
摘要： The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers.
摘要翻译： 本发明提供与人端粒酶逆转录酶（hTRT），人端粒酶的催化蛋白质亚基相关的组合物和方法。 本发明的多核苷酸和多肽可用于人类疾病的诊断，预后和治疗，用于改变细胞和生物体的增殖能力，以及鉴定和筛选用于治疗诸如癌症的疾病的化合物和治疗。
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公开(公告)号：EP1783139B1
公开(公告)日：2009-07-15
申请号：EP06117664.0
申请日：1997-10-01
申请人： GERON CORPORATION
发明人： Cech, Thomas R , Lingner, Joachim , Nakamura, Toru , Chapman, Karen B. , Morin, Gregg, B , Harley, Calvin B. , Andrews, William H.
IPC分类号： C07K4/12
CPC分类号： C12N15/113 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00 , C07K2319/00 , C12N9/1241 , C12N9/1276 , C12N15/1137 , C12N2310/15 , C12N2310/315 , C12Y207/07049 , Y10S530/827 , Y10S530/828
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公开(公告)号：EP1783139A3
公开(公告)日：2007-05-23
申请号：EP06117664.0
申请日：1997-10-01
申请人： GERON CORPORATION
发明人： Cech, Thomas R , Lingner, Joachim , Nakamura, Toru , Chapman, Karen B. , Morin, Gregg, B , Harley, Calvin B. , Andrews, William H.
IPC分类号： C07K4/12
CPC分类号： C12N15/113 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00 , C07K2319/00 , C12N9/1241 , C12N9/1276 , C12N15/1137 , C12N2310/15 , C12N2310/315 , C12Y207/07049 , Y10S530/827 , Y10S530/828
摘要： The invention provides immunogenic peptides of human telomerase reverse transcriptase (hTRT). The peptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of disease such as cancers.
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公开(公告)号：EP0841396B1
公开(公告)日：2003-07-16
申请号：EP97307757.1
申请日：1997-10-01
发明人： Cech, Thomas R. , Lingner, Joachim , Nakamura, Toru , Chapman, Karen B. , Morin, Cregg B. , Harley, Calvin B. , Andrews, William H.
IPC分类号： C12N15/54 , C12N9/12 , C12Q1/68 , C12Q1/48 , C12N15/11 , C12N15/85 , A01K67/027 , C07K16/40 , A61K38/45 , A61K31/70 , C12N1/21 , C12N1/19
CPC分类号： C12N15/113 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00 , C07K2319/00 , C12N9/1241 , C12N9/1276 , C12N15/1137 , C12N2310/15 , C12N2310/315 , C12Y207/07049 , Y10S530/827 , Y10S530/828
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