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公开(公告)号:EP4271674A1
公开(公告)日:2023-11-08
申请号:EP22723850.8
申请日:2022-04-19
发明人: ARMSTRONG, Megan K. , BRIZGYS, Gediminas J. , CASSIDY, James S. , CHIN, Elbert , CHOU, Chienhung , HUNG, Chao-I , LIN, David W. , MITCHELL, Michael L. , ROBERTS, Ezra , SCHROEDER, Scott D. , TAYLOR, James G. , THOMAS-TRAN, Rhiannon , WRIGHT, Nathan E. , YANG, Zheng-Yu
IPC分类号: C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D498/04 , C07D513/04 , A61K31/454 , A61K31/4545 , A61K31/497 , A61K31/4985 , A61K31/506 , A61K31/519 , A61K31/5365 , A61P1/16 , A61P3/04 , A61P3/10
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公开(公告)号:EP4271672A1
公开(公告)日:2023-11-08
申请号:EP22723851.6
申请日:2022-04-19
发明人: ARMSTRONG, Megan K. , CASSIDY, James S. , CHIN, Elbert , CHOU, Chienhung , COTTELL, Jeromy J. , HUNG, Chao-I , KOLAHDOUZAN, Kavoos , LIN, David W. , MITCHELL, Michael L. , ROBERTS, Ezra , SCHROEDER, Scott D. , SHAPIRO, Nathan D. , TAYLOR, James G. , THOMAS-TRAN, Rhiannon , WRIGHT, Nathan E. , YANG, Zheng-Yu
IPC分类号: C07D401/10 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D471/04 , C07D471/08 , C07D487/04 , C07D491/048 , C07D493/04 , C07D493/08 , C07D493/10 , A61K31/4439 , A61K31/444 , A61K31/497 , A61K31/4985 , A61K31/506 , A61K31/5377 , A61P1/16 , A61P3/04 , A61P3/10
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公开(公告)号:EP3159345A1
公开(公告)日:2017-04-26
申请号:EP16190694.6
申请日:2013-07-02
发明人: BJORNSON, Kyla , CANALES, Eda , COTTELL, Jeromy, J. , KARKI, Kapil, Kumar , KATANA, Ashley, Anne , KATO, Darryl , KOBAYASHI, Tetsuya , LINK, John, O. , MARTINEZ, Ruben , PHILLIPS, Barton, W. , PYUN, Hyung-jung , SANGI, Michael , SCHRIER, Adam, James , SIEGEL, Dustin , TAYLOR, James, G. , TRAN, Chinh, Viet , TREJO MARTIN, Teresa, Alejandra , VIVIAN, Randall, W. , YANG, Zheng-Yu , ZABLOCKI, Jeff , ZIPFEL, Sheila
IPC分类号: C07D491/18 , A61P31/14 , A61K31/4995
CPC分类号: A61K31/498 , A61K31/10 , A61K31/401 , A61K31/4745 , A61K31/4985 , A61K31/506 , A61K31/519 , A61K38/00 , A61K38/06 , A61K38/21 , A61K45/06 , C07D241/36 , C07D403/14 , C07D498/16 , C07D498/22 , C07K5/08 , C07K5/0808 , C07K5/0812 , C07K5/0827 , A61K2300/00
摘要: Compounds of Formula (IV), as well as pharmaceutically acceptable salts thereof, are disclosed:
The compounds are useful in the treatment of Hepatitis C infections.摘要翻译: 公开了式(IV)的化合物及其药学上可接受的盐:该化合物可用于治疗丙型肝炎感染。
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公开(公告)号:EP2870160B1
公开(公告)日:2016-09-28
申请号:EP13739324.5
申请日:2013-07-02
发明人: BJORNSON, Kyla , CANALES, Eda , COTTELL, Jeromy, J. , KARKI, Kapil, Kumar , KATANA, Ashley, Anne , KATO, Darryl , KOBAYASHI, Tetsuya , LINK, John, O. , MARTINEZ, Ruben , PHILLIPS, Barton, W. , PYUN, Hyung-jung , SANGI, Michael , SCHRIER, Adam, James , SIEGEL, Dustin , TAYLOR, James, G. , TRAN, Chinh, Viet , TREJO MARTIN, Teresa, Alejandra , VIVIAN, Randall, W. , YANG, Zheng-Yu , ZABLOCKI, Jeff , ZIPFEL, Sheila
IPC分类号: C07D491/18 , A61P31/14 , A61K31/4995 , C07K5/08 , A61K31/506 , A61K31/519 , A61K38/21 , A61K31/4985 , A61K31/4745
CPC分类号: A61K31/498 , A61K31/10 , A61K31/401 , A61K31/4745 , A61K31/4985 , A61K31/506 , A61K31/519 , A61K38/00 , A61K38/06 , A61K38/21 , A61K45/06 , C07D241/36 , C07D403/14 , C07D498/16 , C07D498/22 , C07K5/08 , C07K5/0808 , C07K5/0812 , C07K5/0827 , A61K2300/00
摘要: Compounds of Formula (IV), as well as pharmaceutically acceptable salts thereof, are disclosed: The compounds are useful in the treatment of Hepatitis C infections.
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公开(公告)号:EP2321319B1
公开(公告)日:2012-03-14
申请号:EP09790816.4
申请日:2009-07-24
发明人: AKTOUDIANAKIS, Evangelos , CELEBI, Azim, Alan , DU, Zhimin , JABRI, Salman, Y. , JIN, Haolun , KIM, Choung, U. , LI, Jiayao , METOBO, Samuel, E. , MISH, Michael, R. , PHILLIPS, Barton, W. , SAUGIER, Joseph, H. , YANG, Zheng-Yu , ZONTE, Catalin, Sebastian
IPC分类号: C07D471/16 , C07D498/16 , A61K31/5383 , A61K31/553 , A61K31/551 , A61K31/4375 , A61P31/18
CPC分类号: C07D498/16 , C07D471/16
摘要: The invention is related to anti-viral compounds of formula (I), compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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公开(公告)号:EP2069303A2
公开(公告)日:2009-06-17
申请号:EP07810622.6
申请日:2007-07-19
发明人: CANNIZZARO, Carina, E. , YANG, Zheng-Yu , DESAI, Manoj, C. , MITCHELL, Michael, L. , XU, Lianhong , SWAMINATHAN, Sundaramoorthi , CHEN, James, M.
IPC分类号: C07D213/56 , C07D401/12 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/12
CPC分类号: C07D405/12 , C07D213/56 , C07D401/12 , C07D405/14 , C07D407/12 , C07D409/12 , C07D417/12 , C07D493/04 , C07F9/65583 , C07F9/65586 , C07F9/6561
摘要: The invention is related to compounds of Formula I or a pharmaceutically acceptable salt, solvate, ester, and /or phosphonate thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.
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公开(公告)号:EP4403174A3
公开(公告)日:2024-09-18
申请号:EP24178268.9
申请日:2019-07-11
发明人: AMMANN, Stephen , BACON, Elizabeth, M. , BRIZGYS, Gediminas , CHIN, Elbert , CHOU, Chienhung , COTTELL, Jeromy, J. , NDUKWE, Marilyn , TAYLOR, James G. , WRIGHT, Nathan E. , YANG, Zheng-Yu , ZIPFEL, Sheila M.
IPC分类号: C07F5/02 , C07D487/04
CPC分类号: C07D487/04 , Y02A50/30 , C07F5/025
摘要: A compound of Formula (I):
pharmaceutically acceptable salts thereof, deuterated analogs thereof, compositions thereof, and methods of treating disease using a compound thereof, wherein the variable substituents are disclosed herein.-
公开(公告)号:EP4403174A2
公开(公告)日:2024-07-24
申请号:EP24178268.9
申请日:2019-07-11
发明人: AMMANN, Stephen , BACON, Elizabeth, M. , BRIZGYS, Gediminas , CHIN, Elbert , CHOU, Chienhung , COTTELL, Jeromy, J. , NDUKWE, Marilyn , TAYLOR, James G. , WRIGHT, Nathan E. , YANG, Zheng-Yu , ZIPFEL, Sheila M.
IPC分类号: A61K31/5025
CPC分类号: A61P17/06 , C07D487/04 , Y02A50/30
摘要: A compound of Formula (I):
pharmaceutically acceptable salts thereof, deuterated analogs thereof, compositions thereof, and methods of treating disease using a compound thereof, wherein the variable substituents are disclosed herein.-
公开(公告)号:EP3829588A1
公开(公告)日:2021-06-09
申请号:EP19752359.0
申请日:2019-07-29
发明人: CHIN, Elbert , KATO, Darryl , LINK, John O. , SHAPIRO, Nathan , YANG, Zheng-Yu
IPC分类号: A61K31/55 , A61P31/18 , C07D487/04
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公开(公告)号:EP3159345B1
公开(公告)日:2019-01-09
申请号:EP16190694.6
申请日:2013-07-02
发明人: BJORNSON, Kyla , CANALES, Eda , COTTELL, Jeromy, J. , KARKI, Kapil, Kumar , KATANA, Ashley, Anne , KATO, Darryl , KOBAYASHI, Tetsuya , LINK, John, O. , MARTINEZ, Ruben , PHILLIPS, Barton, W. , PYUN, Hyung-jung , SANGI, Michael , SCHRIER, Adam, James , SIEGEL, Dustin , TAYLOR, James, G. , TRAN, Chinh, Viet , TREJO MARTIN, Teresa, Alejandra , VIVIAN, Randall, W. , YANG, Zheng-Yu , ZABLOCKI, Jeff , ZIPFEL, Sheila
IPC分类号: C07D403/14 , C07D241/36 , A61P31/10 , A61K31/498 , C07K5/08 , A61K31/49
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