摘要:
Novel methods and compositions are provided for the enhanced production of fermentable or known and new β-lactam antibiotics. The process is exemplified by the production of penicillin. In addition, the P.chrysogenum and A.chrysogenum δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine synthetase genes have been isolated and sequenced. Also methods are provided for the production of δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine synthetase using recombined DNA techniques.
摘要:
Novel methods and compositions are provided for the enhanced production of fermentable or known and new secondary metabolites. The process is exemplified for penicillin. In addition, methods are provided for the production of modified P.chrysogenum δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine Synthetase using recombinant DNA techniques.