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公开(公告)号：EP1614471B1
公开(公告)日：2010-08-04
申请号：EP05019225.1
申请日：1999-04-30
发明人： Ammann, Kelly G. , Burns, Ralph E. , Hansberry, Ernest V. , Horner, Glenn A. , Jakub, Cheryl A. , Kling, John E. , Nieglos, Donald J. , Schneider, Robert E. , Smith, Robert J.
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
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2.发明公开System and method for incubating the contents of a reaction receptacle 审中-公开真菌和系统zur Inkubation des Inhalting einesReaktionsbehälters
公开(公告)号：EP2156891A3
公开(公告)日：2010-06-02
申请号：EP09010368.0
申请日：1999-04-30
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： A method for incubating the contents of a reaction receptacle at an incubation temperature within a prescribed temperature range, the method comprising the automated steps of:
providing a reaction receptacle to a temperature ramping station constructed and arranged to adjust the temperature of the contents of the reaction receptacle to approximate the incubation temperature and retaining the reaction receptacle within the temperature ramping station for a predetermined length of time; and
moving the reaction receptacle from the temperature ramping station into an incubator that maintains the contents of the reaction receptacle at the incubation temperature and retaining the reaction receptacle within the incubator for a predetermined period of time.摘要翻译： 一种组件，包括：第一环组件，其构造和布置成可围绕第一旋转轴线旋转，所述第一环组件包括环形流体容器承载部分，其具有限定所述流体容器承载部分的内周和外周， 所述流体容器承载部分被构造和布置成承载多个流体容器; 以及第二环组件，其构造和布置成可独立于所述第一环组件旋转，围绕大体平行于所述第一旋转轴线的第二旋转轴线旋转，所述第二环组件相对于所述第一环组件定位，使得在 所述第二环组件的外周的至少一部分设置在所述第一环组件的所述流体容器承载部分的所述内周边的径向内侧，所述第二环组件被构造和布置成在其上承载多个移液管末端。
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公开(公告)号：EP1614472B1
公开(公告)日：2008-08-13
申请号：EP05019226.9
申请日：1999-04-30
发明人： Ammann, Kelly G. , Burns, Ralph E. , Hansberry, Ernest V. , Horner, Glenn A. , Jakub, Cheryl A. , Kling, John E. , Nieglos, Donald J. , Schneider, Robert E. , Smith, Robert J.
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
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公开(公告)号：EP1930078A1
公开(公告)日：2008-06-11
申请号：EP08152605.5
申请日：1999-04-30
发明人： Ammann, Kelly G. , Burns, Ralph E. , Hansberry, Ernest V. , Horner, Glenn A. , Jakub, Cheryl A. , Kling, John E. , Nieglos, Donald J. , Schneider, Robert E. , Smith, Robert J.
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： The invention relates to a method for keeping a solid support material in suspension within a fluid medium of a container, said method comprising moving said container in a circular path about a first axis of rotation; and simultaneously rotating said container about a second axis of rotation that is generally parallel to said first axis of rotation to thereby keep said solid support material in suspension within said fluid medium of said container by the combined movement and rotation of said container about said first and second axes of rotation.
摘要翻译： 本发明涉及一种用于保持固体支撑材料悬浮在容器的流体介质内的方法，所述方法包括使所述容器围绕第一旋转轴线以圆形路径移动; 同时使所述容器围绕大体上平行于所述第一旋转轴线的第二旋转轴线旋转，从而通过所述容器围绕所述第一和第二旋转轴线的组合运动和旋转而使所述固体支撑材料悬置在所述容器的所述流体介质内 第二旋转轴。
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公开(公告)号：EP2316572A2
公开(公告)日：2011-05-04
申请号：EP10011555.9
申请日：1999-04-30
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next.; The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material, and a device for holding containers of reagents in a temperature controlled environment. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte.
摘要翻译： 用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行测定的离散方面。 分析仪包括用于自动准备标本样品，在规定温度下培养样品规定时间，进行分析物分离程序和确定目标分析物的存在的站。 自动化容器输送系统将反应容器从一个站移动到下一个站; 分析仪还包括用于以机器可接近的方式携带多个样品管和一次性移液管吸头的装置，用于搅拌包含固体支持材料的悬浮液的靶捕获试剂的容器的装置，以及用于将试剂容器保持在温度 受控环境。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化过程。
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6.发明公开
公开(公告)号：EP2316570A2
公开(公告)日：2011-05-04
申请号：EP10012007.0
申请日：1999-04-30
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and a device for holding containers of reagents in a temperature controlled environment. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte.
摘要翻译： 用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行测定的离散方面。 分析仪包括用于自动准备标本样品，在规定温度下培养样品规定时间，进行分析物分离程序和确定目标分析物的存在的站。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可访问的方式携带多个样品管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液的靶捕获试剂的容器的装置和用于将试剂容器保持在受温度控制的装置 环境。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化过程。
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7.发明公开
公开(公告)号：EP2156891A2
公开(公告)日：2010-02-24
申请号：EP09010368.0
申请日：1999-04-30
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： A method for incubating the contents of a reaction receptacle at an incubation temperature within a prescribed temperature range, the method comprising the automated steps of:
providing a reaction receptacle to a temperature ramping station constructed and arranged to adjust the temperature of the contents of the reaction receptacle to approximate the incubation temperature and retaining the reaction receptacle within the temperature ramping station for a predetermined length of time; and
moving the reaction receptacle from the temperature ramping station into an incubator that maintains the contents of the reaction receptacle at the incubation temperature and retaining the reaction receptacle within the incubator for a predetermined period of time.摘要翻译： 一种用于在预定温度范围内的温育温度下孵育反应容器的内容物的方法，所述方法包括以下自动化步骤：将反应容器提供给构建和设置成调节反应内容物温度的温度缓变站 容器接近温育温度并将反应容器保持在升温台内预定的时间长度; 以及将反应容器从升温台移动到孵化器中，该孵育器将反应容器的内容物维持在孵育温度并将反应容器保持在恒温箱内预定的时间段。
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公开(公告)号：EP1614470B1
公开(公告)日：2009-03-25
申请号：EP05015156.2
申请日：1999-04-30
发明人： Ammann, Kelly G. , Burns, Ralph E. , Hansberry, Ernest V. , Horner, Glenn A. , Jakub, Cheryl A. , Kling, John E. , Nieglos, Donald J. , Schneider, Robert E. , Smith, Robert J.
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
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9.发明公开Device for agitating the fluid contents of a container 有权Rührvorrichtungfürden fluiden Inhalt einesBehälters
公开(公告)号：EP1614475A3
公开(公告)日：2006-02-08
申请号：EP05019229.3
申请日：1999-04-30
发明人： Ammann, Kelly G. , Burns, Ralph E. , Hansberry, Ernest V. , Horner, Glenn A. , Jakub, Cheryl A. , Kling, John E. , Nieglos, Donald J. , Schneider, Robert E. , Smith, Robert J.
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： A device for agitating the fluid contents of at least one container, said device comprising:
a turntable structure constructed and arranged to be rotatable about a first axis of rotation;
one or more container holders, each of said container holders having an axis of rotation and being constructed and arranged to hold a container therein, said container holders being mounted on said turntable structure so as to be rotatable therewith and so that said axis of rotation of each container holder is generally parallel to said first axis of rotation;
a container holder mounting assembly associated with each container holder, said container holder mounting assembly being constructed and arranged to mount said associated container holder to said turntable structure and to permit said associated container holder to rotate about a second axis of rotation that is generally parallel to and spaced from both said first axis of rotation and said axis of rotation of said associated container holder; and
rotational motion coupling elements operatively associated with said turntable structure and said container holder mounting structure and constructed and arranged to cause each container holder to rotate about said second axis of rotation as said turntable structure rotates about said first axis of rotation.摘要翻译： 一种组件，包括：第一环组件，其构造和布置成可围绕第一旋转轴线旋转，所述第一环组件包括环形流体容器承载部分，其具有限定所述流体容器承载部分的内周和外周， 所述流体容器承载部分被构造和布置成承载多个流体容器; 以及第二环组件，其构造和布置成可独立于所述第一环组件旋转，围绕大体平行于所述第一旋转轴线的第二旋转轴线旋转，所述第二环组件相对于所述第一环组件定位，使得在 所述第二环组件的外周的至少一部分设置在所述第一环组件的所述流体容器承载部分的所述内周边的径向内侧，所述第二环组件被构造和布置成在其上承载多个移液管末端。
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公开(公告)号：EP2316571A3
公开(公告)日：2011-07-27
申请号：EP10011529.4
申请日：1999-04-30
CPC分类号： C12Q1/6834 , B01F9/0001 , B01F9/0014 , B01F9/0021 , B01F2009/0074 , B01L7/52 , B01L7/5255 , B01L9/06 , B01L2200/147 , B01L2300/1822 , B01L2300/1827 , B03C1/282 , B03C1/288 , B03C1/30 , B03C2201/26 , C12Q1/6813 , C12Q1/6832 , C12Q2537/10 , G01N35/0098 , G01N35/0099 , G01N35/025 , G01N35/1065 , G01N2035/00356 , G01N2035/00524 , G01N2035/0437 , G01N2035/0455 , G01N2035/103 , Y10T29/53657 , Y10T29/53683 , Y10T29/53843 , Y10T156/1105 , Y10T156/1906 , Y10T436/11 , Y10T436/111666 , Y10T436/113332 , Y10T436/114998 , Y10T436/119163 , Y10T436/2575
摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and a device for holding containers of reagents in a temperature controlled environment. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte.
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