公开(公告)号：EP1263948A2

公开(公告)日：2002-12-11

申请号：EP00907314.9

申请日：2000-02-18

申请人： Genentech, Inc.

发明人： ASZKENAZI, Avi J. ,  BAKER, Kevin P. ,  BOTSTEIN, David ,  DESNOYERS, Luc ,  EATON, Dan L. ,  FERRARA, Napoleone ,  FILVAROFF, Ellen ,  FONG, Sherman ,  GAO, Wei-Qiang ,  GERBER, Hanspeter ,  GERRITSEN, Mary E. ,  GODDARD, Audrey ,  GODOWSKI, Paul J. ,  GRIMALDI, Christopher G. ,  GURNEY, Austin L. ,  HILLAN, Kenneth J. ,  KLJAVIN, Ivar J. ,  KUO, Sophia S. ,  NAPIER, Mary A. ,  PAN, James ,  PAONI, Nicholas F. ,  ROY, Margaret Ann ,  SHELTON, David L. ,  STEWART, Timothy A. ,  TUMAS, Daniel ,  WILLIAMS, P. Mickey ,  WOOD, William I.

IPC分类号： C12N15/12 ,  C12N15/63 ,  C12N5/10 ,  C12N1/21 ,  C12N1/19 ,  C07K14/47 ,  C07K14/705 ,  C07K19/00 ,  C07K16/18 ,  C07K16/28 ,  G01N33/68 ,  G01N33/543 ,  A61K47/48 ,  A61K51/08 ,  A61K38/17

CPC分类号： C07K16/18 ,  A61K38/00 ,  A61K47/64 ,  C07K14/47 ,  C07K14/4703 ,  C07K14/705 ,  C07K14/70578 ,  C07K16/28 ,  C07K2317/24 ,  C07K2319/00 ,  C12N2799/026 ,  C12N2799/027

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。 本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法 发明。

公开(公告)号：EP1578371A2

公开(公告)日：2005-09-28

申请号：EP03788626.4

申请日：2003-08-19

申请人： GENENTECH, INC.

发明人： DESAUVAGE, Frederic J. ,  FRANTZ, Gretchen ,  HILLAN, Kenneth J. ,  POLAKIS, Paul ,  POLSON, Andrew ,  SMITH, Victoria ,  SPENCER, Susan D. ,  WU, Thomas D. ,  ZHANG, Zemin

IPC分类号： A61K6/00

CPC分类号： C07K16/30 ,  A61K47/6803 ,  A61K47/6809 ,  A61K47/6843 ,  A61K47/6851 ,  A61K2039/505

摘要： The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.