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公开(公告)号:EP2152748A1
公开(公告)日:2010-02-17
申请号:EP08768087.2
申请日:2008-06-03
申请人: Genentech, Inc.
发明人: SIEBEL, Christian, W. , WU, Yan
IPC分类号: C07K16/28 , A61K39/395 , A61P37/00 , A61K35/00 , A61P21/00 , A61P43/00 , C12N15/13 , A61P25/28 , C12N15/73 , C12N1/21
CPC分类号: C07K16/30 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K14/705 , C07K14/71 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K16/3015 , C07K2317/14 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C12N5/10 , C12N5/12 , C12N15/09 , C12N15/63 , C12N2330/50
摘要: The invention provides anti-Notch 1 NRR antibodies, and compositions comprising and methods of using these antibodies.
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公开(公告)号:EP2334331A1
公开(公告)日:2011-06-22
申请号:EP09793181.0
申请日:2009-09-30
发明人: SIEBEL, Christian, W. , WU, Yan
IPC分类号: A61K39/395 , A61P35/00 , C07K16/28
CPC分类号: C07K16/28 , A61K2039/505 , C07K16/30 , C07K16/3053 , C07K2317/21 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2319/00
摘要: The invention provides anti-Notch antibodies, and in particular, antibodies that bind Notch2 NRR, and methods of using the same.
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公开(公告)号:EP2152748B1
公开(公告)日:2013-08-21
申请号:EP08768087.2
申请日:2008-06-03
申请人: Genentech, Inc.
发明人: SIEBEL, Christian, W. , WU, Yan
IPC分类号: C07K16/28 , A61K39/395 , A61P37/00 , A61K35/00 , A61P21/00 , A61P43/00 , C12N15/13 , A61P25/28 , C12N15/73 , C12N1/21
CPC分类号: C07K16/30 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K14/705 , C07K14/71 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K16/3015 , C07K2317/14 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C12N5/10 , C12N5/12 , C12N15/09 , C12N15/63 , C12N2330/50
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