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1.ANTIBODIES AGAINST BACE1 AND USE THEREOF FOR NEURAL DISEASE IMMUNOTHERAPY 审中-公开
标题翻译: 抗BACE1抗体及其用于神经疾病免疫治疗公开(公告)号:EP3221364A1
公开(公告)日:2017-09-27
申请号:EP15805020.3
申请日:2015-11-18
申请人: Genentech, Inc. , Adimab, LLC
发明人: LIU, Yichin , ATWAL, Jasvinder , CHIU, Cecilia Pui Chi , WATTS, Ryan J. , WU, Yan , KRAULAND, Eric , FELDHAUS, Michael
IPC分类号: C07K16/40 , A61K39/395 , A61P25/28
CPC分类号: C07K16/40 , A61K47/6871 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K2317/21 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C12Y304/23046 , G01N33/573 , G01N2333/96472 , G01N2800/28 , G01N2800/52
摘要: The invention provides antagonistic antibodies to BACE1 and methods of using the same for the treatment of neurological disease and disorders.
摘要翻译: 本发明提供了针对BAC1的拮抗性抗体及其用于治疗神经疾病和病症的方法。
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2.ANTI-TRANSFERRIN RECEPTOR / ANTI-BACE1 MULTISPECIFIC ANTIBODIES AND METHODS OF USE 审中-公开
标题翻译: 抗转铁蛋白受体/抗BACE1多特异性抗体及使用方法公开(公告)号:EP3221361A1
公开(公告)日:2017-09-27
申请号:EP15804651.6
申请日:2015-11-18
申请人: Genentech, Inc. , Adimab, LLC
发明人: LIU, Yichin , ATWAL, Jasvinder , CHIU, Cecilia Pui Chi , WATTS, Ryan J. , WU, Yan , KRAULAND, Eric , FELDHAUS, Michael , ZHANG, Yin , ZUCHERO, Joy Yu , COUCH, Jessica , DENNIS, Mark S. , ERNST, James A. , LAZAR, Gregory A.
CPC分类号: C07K16/40 , A61K2039/505 , C07K16/2881 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/41 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/528 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , C07K2319/00 , C12Y304/23046 , G01N33/6896 , G01N2333/70582 , G01N2333/96472 , G01N2800/28 , G01N2800/52
摘要: The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.
摘要翻译: 本发明涉及结合转铁蛋白受体和BACE1的双特异性抗体及其使用方法。
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公开(公告)号:EP3845565A3
公开(公告)日:2021-09-08
申请号:EP20204109.1
申请日:2015-11-18
申请人: Genentech, Inc. , Adimab, LLC
发明人: LIU, Yichin , ATWAL, Jasvinder , CHIU, Cecilia Pui Chi , WATTS, Ryan J. , WU, Yan , KRAULAND, Eric , FELDHAUS, Michael
IPC分类号: C07K16/40 , A61K39/395 , A61P25/28
摘要: The invention provides antagonistic antibodies to BAC1 and methods of using the same for the treatment of neurological diseases and disorders.
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公开(公告)号:EP3845565A2
公开(公告)日:2021-07-07
申请号:EP20204109.1
申请日:2015-11-18
申请人: Genentech, Inc. , Adimab, LLC
发明人: LIU, Yichin , ATWAL, Jasvinder , CHIU, Cecilia Pui Chi , WATTS, Ryan J. , WU, Yan , KRAULAND, Eric , FELDHAUS, Michael
IPC分类号: C07K16/40 , A61K39/395 , A61P25/28
摘要: The invention provides antagonistic antibodies to BAC1 and methods of using the same for the treatment of neurological diseases and disorders.
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公开(公告)号:EP4360646A3
公开(公告)日:2024-05-15
申请号:EP23209560.4
申请日:2016-09-23
发明人: GROGAN, Jane L. , JOHNSTON, Robert J. , WU, Yan , LIANG, Wei-Ching , LUPARDUS, Patrick , YADAV, Mahesh , SESHASAYEE, Dhaya , HAZEN, Meredith
IPC分类号: C07K16/28 , A61K39/00 , A61K38/17 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/02 , A61P37/04 , A61P43/00
CPC分类号: A61K2039/50520130101 , C07K2317/3320130101 , C07K2317/3420130101 , C07K2317/7020130101 , C07K2317/9020130101 , C07K16/28 , A61K38/177 , C07K2317/9220130101 , C07K2317/7620130101 , C07K2317/9420130101 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/02 , A61P37/04 , A61P43/00 , Y02A50/30
摘要: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:EP4182348A1
公开(公告)日:2023-05-24
申请号:EP21755151.4
申请日:2021-07-16
申请人: Genentech, Inc.
发明人: CHIU, Cecilia Pui Chi , WU, Yan , ELSOHLY, Adel Mahmoud , LAFKAS, Daniel George , PAYANDEH, Jian Mehr-Dean , TSAI, Siao-Ping , HO, Hoangdung Dang
IPC分类号: C07K16/28 , A61P11/00 , A61K39/395
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公开(公告)号:EP3191518A1
公开(公告)日:2017-07-19
申请号:EP15767037.3
申请日:2015-09-11
申请人: Genentech, Inc.
发明人: LEONG, Steven R. , POLSON, Andrew , POLAKIS, Paul , WU, Yan , LIANG, Wei-Ching , FIRESTEIN, Ron
CPC分类号: C07K16/2827 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , A61K47/6803 , A61K47/6809 , A61K47/6855 , A61K47/6869 , A61K2039/505 , C07K16/3015 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/57492
摘要: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
摘要翻译: 本发明提供了抗B7-H4抗体和免疫缀合物及其使用方法。
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8.BINDING POLYPEPTIDES WITH DIVERSIFIED AND CONSENSUS VH/VL HYPERVARIABLE SEQUENCES 有权
标题翻译: 结合多肽具有多样化和共识的VH / VL高变序列公开(公告)号:EP1957531B1
公开(公告)日:2016-04-13
申请号:EP06837138.4
申请日:2006-11-07
申请人: Genentech, Inc.
发明人: DENNIS, Mark , LIANG, Wei-Ching , WU, Yan
CPC分类号: C07K16/005 , C07K16/32 , C07K2317/21 , C07K2317/24 , C07K2317/56
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公开(公告)号:EP1989231B1
公开(公告)日:2015-05-20
申请号:EP07868188.9
申请日:2007-03-21
申请人: Genentech, Inc.
IPC分类号: C07K16/22 , C07K16/28 , A61K39/395 , G01N33/573 , G01N33/50 , G01N33/68 , A61P35/00
CPC分类号: A61K39/3955 , A61K45/06 , A61K51/1093 , A61K2039/505 , A61K2039/507 , C07K16/22 , C07K16/2842 , C07K2317/73 , C07K2317/76 , C07K2317/92 , G01N33/74
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公开(公告)号:EP2468772A3
公开(公告)日:2013-01-23
申请号:EP11195410.3
申请日:2007-03-16
申请人: GENENTECH, INC.
发明人: YE, Weilan , SCHMIDT, Maike , HONGO, Jo-Anne , WU, Yan
CPC分类号: C07K16/22 , A61K2039/505 , A61K2039/507 , C07K2317/56 , C07K2317/565 , C07K2317/73
摘要: The invention provides anti-EGFL7 antibodies, and compositions comprising and methods of using these antibodies.
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