公开(公告)号：EP1339401A1

公开(公告)日：2003-09-03

申请号：EP01981643.8

申请日：2001-10-16

申请人： Guritza, Dennis A.

发明人： Guritza, Dennis A.

IPC分类号： A61K31/32 ,  A61K31/30 ,  A61K31/295 ,  C12N1/00 ,  C12N1/38 ,  C12N1/20 ,  C12N1/18

CPC分类号： B32B27/08 ,  A61L2/0082 ,  B08B17/00 ,  B32B9/04 ,  B32B27/36 ,  B32B27/40 ,  B32B2363/00 ,  B32B2367/00 ,  B32B2375/00 ,  C08K5/0058 ,  C09D5/1612 ,  Y10T428/31504 ,  Y10T428/31511 ,  Y10T428/31515 ,  Y10T428/31551 ,  Y10T428/31663 ,  Y10T428/31678 ,  Y10T428/31786 ,  Y10T428/31938 ,  Y10T428/31989 ,  Y10T428/4935 ,  Y10T428/662 ,  Y10T428/8305

摘要： A stenophiluric media is provided containing at least one bio-limiting agent such as a copper, tin, nickel or alloy thereof. The media may be formed of a polymer such as a thermoplastic polymer. The polymer may be an epoxy resin, a polyester resin, a polyurethane resin or an aminoplast resin. The media may also be formed of an amalgam of naturally occuring tars and resins. In an embodiment, the polymer is a crosslinked polyepoxide prepared from an epoxy resin and a polyamine crosslinking agent. The media may also contain a nutrient source. The media is used to prevent fouling by applying a coating of the media to a substrate such as a the hull of a boat or ship, a culvert or piping or a surface in a fermentation vessel, and allowing a selected biomass to form on the media. The selected biomass produces allelopathic chemicals that prevent attachment of higher animals.

公开(公告)号：EP2110143A2

公开(公告)日：2009-10-21

申请号：EP09154163.1

申请日：2001-10-16

申请人： Guritza, Dennis A.

发明人： Guritza, Dennis A.

IPC分类号： A61L2/00 ,  B08B17/00 ,  B27K5/00 ,  C08K5/00 ,  C09D5/16

CPC分类号： B32B27/08 ,  A61L2/0082 ,  B08B17/00 ,  B32B9/04 ,  B32B27/36 ,  B32B27/40 ,  B32B2363/00 ,  B32B2367/00 ,  B32B2375/00 ,  C08K5/0058 ,  C09D5/1612 ,  Y10T428/31504 ,  Y10T428/31511 ,  Y10T428/31515 ,  Y10T428/31551 ,  Y10T428/31663 ,  Y10T428/31678 ,  Y10T428/31786 ,  Y10T428/31938 ,  Y10T428/31989 ,  Y10T428/4935 ,  Y10T428/662 ,  Y10T428/8305

摘要： This invention relates to an article comprising a bio-supportive media which bio-degrades at a preferred rate, comprising at least one bio-limiting agent and at least one nutritional source on a substrate. The media may be characterized as a polymer, composite, or amalgam of commonly used materials. The invention relates to altering the physical/chemical composition of the media such that bio-degradation can occur at a specific, usually accelerated, preferred rate. Further, the bio-degradation rate may be managed and balance concurrently with the ability to provide for the exposure of integral component(s) which are bio-active. This relationship essentially provides for a managed release or managed availability of agent(s) which creates a hew set of ecological conditions. These sustained conditions can maintain a micro-habitat; a limited consort of species, often slime which, due to this ecological trophic niche position, can utilize innate allelopathic means to further protect their position and deter predation. The relationships of the nutrients, blo-limiters, and biomass comprise a unique micro-habitat as an interface which provides protection from corrosion and deterioration of the substrate upon which it is fixed, and limits the biomass accumulation on the surface thereby providing control of fouling by reducing higher order organism(s) attachments, which otherwise are very economically costly.
Specifically the invention relates to modifying the media formation whether as a polymer or composite or amalgam such that the physical and chemical properties of the media are altered to become more degradable in the host habitat. This is accomplished by altering the polymerization or formation of the composite or amalgam to provide for increased inter-granular or molecular locations which permit enhanced bio-degradative activity. Then by occluding or interspersing physical or chemically an agent which has bio-active properties, the organisms of various species which may attach or be attracted to the surface can be limited by their nutrition and tolerance of bio-active preference without the need for toxification or mechanical removal of undesirable or unwanted organism as settlers. Once the community of selected organisms establishes a natural equilibrium with the host habitat any capacity for allelopathic protection of the biofilm can be utilized or enhanced by this new and unique biological community to its benefit through management of the media components.

摘要翻译： 本发明涉及包含以优选速率生物降解的生物支持介质的制品，其包含至少一种生物限制剂和至少一种营养源。 介质可以被表征为常用材料的聚合物，复合材料或汞齐。 本发明涉及改变介质的物理/化学组成，使得生物降解可以以特定的，通常加速的优选速率发生。 此外，生物降解速率可以与提供暴露于生物活性的整体组分的能力同时进行管理和平衡。 这种关系基本上提供了一个管理的释放或管理可用的代理，它们创建了一组生态条件。 这些持续的条件可以保持微观栖息地; 一个有限的物种共同体，通常由于这个生态营养利基的位置，可以利用天生的化感手段来进一步保护自己的位置并阻止捕食。 营养物，限制器和生物质的关系包括独特的微栖息地作为界面，其提供保护以防止其固定在其上的基底的腐蚀和劣化，并限制生物质在表面上的积聚，从而提供污垢控制 通过减少高阶生物附件，否则这些附件在经济上是非常昂贵的。 具体地说，本发明涉及改变介质形成，无论是聚合物还是复合材料或汞齐，使得介质的物理和化学性质被改变以在宿主栖息地中变得更可降解。 这是通过改变复合物或汞齐的聚合或形成来实现的，以提供允许增强的生物降解活性的增加的颗粒间或分子位置。 然后通过将具有生物活性的物质物理或化学的物质或化学物质封闭或散布，可能附着或被吸引到表面的各种物质的生物体可受其生物活性偏好的营养和耐受性的限制，而不需要毒素或 机械去除不想要的或不需要的生物作为定居者。 一旦所选生物体的社区与宿主栖息地建立了自然平衡，那么这种新的和独特的生物群落的任何能够利用或增强生物膜的抗病性保护能力，可以通过管理媒体成分来获益。

公开(公告)号：EP1476535A2

公开(公告)日：2004-11-17

申请号：EP03708961.2

申请日：2003-02-05

申请人： Guritza, Dennis A.

发明人： Guritza, Dennis A.

IPC分类号： C12M1/00 ,  C12M3/00

CPC分类号： C12M25/00

摘要： Stenoprophiluric media provide for the creation and sustained well being of micro-habitats in uncontrolled host habitats in order to study the biological, biochemical and physical (morphological) properties of the organisms and their consortiums inherently and/or in relationship to competing or proximal micro-habitats as well. Given this in-situ method of study of these consortiums; sampling of metabolic bio-chemicals both primary and secondary is readily achieved. By providing this medium or platform for natural in-situ evaluation of varying host habitats and/or multiple sub-habitats ( micro-habitats) in the same host habitat, conditions and changing relationships can be evaluated; physically, biologically, and chemically. Evaluation enhancements by this method provides for the ability to sample discrete chemicals or groups of chemicals and/or compounds for easy bio-activity evaluation. Further, morphological and taxonomic evaluation of micro-habitats is permitted whereby, relationships and evaluation of changes in settling, growth, or mature bio-film formations can be readily accomplished.

公开(公告)号：EP1223810A1

公开(公告)日：2002-07-24

申请号：EP00973955.8

申请日：2000-10-20

申请人： Guritza, Dennis A.

发明人： Guritza, Dennis A.

IPC分类号： A01N63/00 ,  C12P1/00 ,  C12N11/02 ,  C12N11/08 ,  C12N11/04 ,  D06M16/00

CPC分类号： C12N11/08 ,  A01N59/16 ,  A01N59/20 ,  A01N63/00 ,  C12N1/12 ,  C12N1/20 ,  C12N11/00 ,  C12N11/02 ,  C12P1/00 ,  Y10T428/31511 ,  Y10T428/31522 ,  A01N59/00 ,  A01N25/34 ,  A01N25/10 ,  A01N2300/00

摘要： This invention relates to an article comprising a bio-supportive matrix comprising at least one bio-limiting agent and at least one nutritional source on a substrate. The invention also relates to the bio-supportive matrix and methods of using the matrix. The present invention can be used as a biological barrier to unwanted organisms, such as animals and plants, by producing allelochemicals that either kill or repel those organisms. The invention could be used as a coating on a vessel to prevent fouling of vessels. The invention may also be used to manufacture specific allelochemicals such as drugs or pharmaceuticals. The invention also relates to a method of preparing a bio-limiting ecological substrate useful as a means for producing allelochemicals, comprising the steps of providing a bio-supportive matrix as described above, and exposing the matrix to the environment, wherein the matrix is prepared to provide a biomass that produces the desired allelochemicals. The bio-supportive matrix provides a durable support layer for a biomass. The biomass may be selected to produce specific allelochemicals that have pharmaceutical or organism inhibiting properties.